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En ökning av andelen kollektivtrafik är en viktig del av omställningen mot lägre utsläpp av växthusgaser och mer energieffektiva transporter. I Sverige har antalet resor med kollektivtrafiken ökat med 18% mellan åren 2009 och 2015. Det finns dock en stor skillnad mellan olika regioner där ökningen varit över 20% i flera regioner medan utvecklingen av resandet har stagnerat, eller till och med mins

Behandling av patienter med alkohol- eller drogberoende är en komplex flerstegsprocess som behandlar både substansberoende och co-morbiditeter. Riskfyllda livsstilar, inklusive tobaksrökning, otillräcklig fysisk aktivitet och ohälsosam kost, som kan förvärra hälsotillståndet och själva beroendebehandlingen, är mycket vanligt bland dessa patienter. Det komplexa hälsofrämjande programmet (Very IntegTreatment of patients with alcohol or drug use disorders is a complex multistage process addressing the substance addiction and co-morbidities. The risky lifestyles, including tobacco smoking, insufficient physical activity and unhealthy diet, which can aggravate health condition as well as addiction treatment itself, are very common among these patients. The complex health promotion (Very Integra

Temperature and precipitation extremes are the dominant causes of natural disasters. In this study, seven indices of extreme temperature and precipitation events in Gansu Province, China, were analysed for the period 1961–2017. An abrupt climate shift was recorded during 1980–1981. Thus, the study period was divided into a preshift (before the climate shift) period 1961–1980 and an aftshift (after

An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbourin

This article presents the methodological requirements for clinical examination and patient-reported outcomes measurements. The assessment of any measurement for clinical research in hand surgery is difficult. A method of measuring a criterion could be 100% reliable but 100% invalid. Bias may be present in our assessment if we do not take into account the methodological requirements related to reli

Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insulin deficiency and type 1 diabetes (T1D)1-4. Certain enteroviruses can infect β cells in vitro5, have been detected in the pancreatic islets of patients with T1D6 and have shown an association with T1D in meta-analyses4. However, establishing consistency in findings across studies has proven difficul

On the 20th anniversary of the euro, this column traces public support for the single currency and public trust in the ECB. The crisis years slightly dented support for the euro while trust in the ECB fell sharply. The recovery increased support for the euro, but while trust in the ECB has also risen, it remains below its pre-crisis levels. Unemployment is the key factor driving public support for

Ecdysteroids are critically important for formation of the insect exoskeleton. Cholesterol is a precursor of ecdysone and its active form 20-hydroxyecdysone, but some steps in the ecdysteroid biosynthesis pathway remain unknown. An essential requirement of glutathione transferase GSTE14 in ecdysteroid biosynthesis has been established in Drosophila melanogaster, but its function is entirely unknow

User generated content (UGC) makes up a significant portion of Internet traffic. As opposed to other content, UGC has so far been left outside over-the-top providing network operators content distribution networks (telco-CDN) due to the difficulty in determining optimised placement of such content. The side effect of this is that UGC content is not placed close to end users and therefore occupy un

Vegetation growth in Soil and Water Assessment Tool (SWAT) is a crucial process for quantifying ecohydrological modelling, as it influences evapotranspiration, interception, soil erosion and biomass production. The simplified version of Environmental Policy Integrated Climate (EPIC) in SWAT was originally designed for temperate regions and naturally based on temperatur

Precipitation data at high spatio-temporal resolution are essential for hydrological, meteorological, and ecological research in local basins and regions. The coarse spatial resolution (0.25°) of Tropical Rainfall Measuring Mission (TRMM) 3B43 product is insufficient for practical requirements. In this paper, a multivariable geographically weighted regression (GWR) downscaling method was developed

The cover and management factor (C) of the Universal Soil Loss Equation (USLE) is difficult to be estimated over broad geographic areas where meteorology and soil erosion are poorly monitored. This paper presents a new approach to estimate C factor based on multi-temporal images of Landsat TM/ETM and a weather generator. The linear spectral unmixture algorithm was adopted to calculate the fraction

Standard Model events with prompt, isolated, same-charge high-pT leptons are rare, and therefore events with such final states provide a powerful signature towards new discoveries. This thesis presents two searches for doubly charged Higgs bosons decaying into same-charge lepton pairs using proton–proton collision data recorded by the ATLAS detector at the LHC. Observation of doubly charged Higgs

The galectins are a family of galactose-binding proteins playing key roles in inflammatory processes and cancer. However, they are structurally very closely related, and discovery of highly selective inhibitors is challenging. In this work, we report the design of novel inhibitors binding to a subsite unique to galectin-3, which confers both high selectivity and affinity towards galectin-3. Olefin

Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology has remained controversial mainly due to the lack of serological methods that can distinguish the two viruses. A novel multiplex serological assay measuring IgG reactivity against the immediate-early protein 1 from HHV-6A (IE1A) and HHV-6B (IE1B) was used in a MS cohort (8,742 persons with MS and 7,215 matched con

The nature of today’s business demands that Business Analytics (BA) extends to an operational level to better support employees in their decision-making. This is noticeable from the constant requests for new reports and changes in old ones at different employee levels. As a result, BA specialists or other power-users in functional departments are “bombarded” by these requests, and it becomes more