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The purpose of this study was to develop a method to simulate breathing motion induced interplay effects for volumetric modulated arc therapy (VMAT), to verify the proposed method with measurements, and to use the method to investigate how interplay effects vary with different patient- and machine specific parameters. VMAT treatment plans were created on a virtual phantom in a treatment planning s
Background: Epidemiological studies have shown that many welders experience respiratory symptoms. During the welding process a large number of airborne nanosized particles are generated, which might be inhaled and deposited in the respiratory tract. Knowledge of the underlying mechanisms behind observed symptoms is still partly lacking, although inflammation is suggested to play a central role. Th
Background: Sex workers have high incidences of HIV and other sexually transmitted diseases. Although, interventions targeting sex workers have shown to be effective, evidence on which strategies are most cost-effective is limited. This study aims to systematically review evidence on the cost-effectiveness of sexual health interventions for sex workers on a global level. It also evaluates the qual
Popular Abstract in Swedish Hårdvara och algoritmer för ett inbyggt videoövervakningssystem presenteras i denna avhandling. För att verifiera systemet så har en prototyp byggts.The demands on video surveillance systems are rapidly increasing regarding parameters such as frame rate and resolution. Furthermore, with an ever increasing number of video streams, an automated process for extracting relevant information is required. Due to the large amount of input data and the computational complexity of the algorithms, software implementations are not sufficient to sustain re
Purpose: Recently, there has been a growing interest in operating medical linear accelerators without a flattening filter Due to reduced scatter, leaf transmission and radiation head leakage a reduction of out-of-field dose is expected for flattening filter free beams. The aim of the present study was to determine the impact of unflattened beams on peripheral dose for advanced treatment techniques
Background. Solid organ transplants (SOTs) are life-saving interventions, recently challenged by coronavirus disease 2019 (COVID-19). SOTs require a multistep process, which can be affected by COVID-19 at several phases.Methods. SOT-specialists, COVID-19-specialists, and medical ethicists designed an international survey according to CHERRIES guidelines. Personal opinions about continuing SOTs, sa
BACKGROUND: The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult. Patients eventually presenting with clinically apparent PC have a poor prognosis. Median survival is only about five months if untreated and the benefit of palliative systemic chemotherapy is limited. Only a quarter of patients are
Among nanoscale structures of different shapes and dimensions nanowires are one of the most promising because of its truly unique properties different from their bulk counterparts. The energy quantization, perfect defect-free structure, and the possibility to grow them within the miscibility gap in combination with the benefits of bottom-up design and the possibility of integration on silicon subs
Background: After neoadjuvant chemotherapy (NAC), about 20% of pts with muscle-invasive UC are found to have advanced pT-stage or lymph node involvement and 5-year overall survival (OS) of them is < 30%. Tumor samples from these pts may provide information about chemotherapy resistance, and may predict for the activity of new drugs given postoperatively. Alterations of FGFR3 gene represent a thera
This thesis is based on work done by the author on the development of plasma-based electron accelerators driven by ultra-intense laser pulses and dense electron bunches. Plasma based accelerators have several benefits, such as accelerating fields around 1000 times stronger than in “conventional” radio-frequency accelerators, which can allow for shrinking the overall footprint of the accelerator. T
ABSTRACT: BACKGROUND: There is an insufficient number of reliable prognostic and response predictive biomarkers in colorectal cancer (CRC) management. In a previous study, we found that high tumour tissue expression of tumour-associated trypsin inhibitor (TATI) correlated with liver metastasis and an impaired prognosis in CRC. The aim of this study was to investigate the prognostic validity of ser
Popular Abstract in Swedish Populariteten av karttjänster, t.ex. på Internet, ökar ständigt. Detta beror till stor del på en hela tiden förbättrad teknik och ett ökande antal idéer för kartapplikationer. Exempel på kartapplikationer är: positioneringstjänster, navigationstjänster, och tjänster för att söka efter, titta på och ladda ner geografiska data och kartor. Kartorna i dessa tjänster skapas The research presented in this thesis has focused on methods for improving the legibility and usability of maps in real-time map services. The aim has been threefold: to create methods to increase the cartographic quality of maps in map services, to develop methods to measure the legibility, as perceived by the user, and to evaluate the quality of maps. Map services are becoming increasingly commo
* This workshop’s long term goal is to foster a community of Information Systems researchers and practitioners who are interested in the socio-technical perspective and see it as an important approach to improve the quality and reduce the costs of the information systems that have become an essential part of our lives in this 21st century. All communities need meeting places where they can discuss
Popular science summary Spatial Memory Accuracy in Marsh tits (Poecile palustris) - an experimental study Food hoarding is a prevalent food protection behaviour in nature and it is performed by variety of animals including some mammals and birds. Two main food hoarding strategies have been observed among animals; larder hoarding and scatter hoarding. Larder hoarders aggregate all their food in
The purpose of this study was to investigate social workers’ experience of communicating with children using an interpreter and analysing the challenges. We conducted qualitative interviews with the focus groups of social workers in a city in the southern part of Sweden. They all served at the social services in the municipality. Totally, four focus group interviews were conducted with four partic
The purpose of this essay was to examine how professional social workers work with follow up foster home placements. The study was based on qualitative interviews with ten professional social workers from different municipalities in Skåne in an attempt to answer the following questions: * What routines exist for the follow-up work with foster care? * What factors have an impact on how the follow
The International Labour Organization (ILO) was created in 1919 and this organization is the main global actor as regards the creation and supervision of labour standards. The combination of the regular work of the ILO in assisting member countries to comply with labour standards and its multifaceted supervising system has made ILO a successful organization in developing and implementing the human
In this thesis, I critically explore the ways in which people consume extraordinary experiences and what this can tell us about contemporary society. My findings question the idea that extraordinary experiences are an escape from the demands of everyday life. I show instead that social (especially neoliberal) discourses discipline endurance runners and shape the ways in which they understand and a
The transcription factor MYC is a well-described oncogene with an important role in lymphomagenesis, but its significance for clinical outcome in mantle cell lymphoma (MCL) remains to be determined. We performed an investigation of the expression of MYC protein in a cohort of 251 MCL patients complemented by analyses of structural aberrations and mRNA, in a sub-cohort of patients. Fourteen percent
