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Release of halide ions is an essential step of the catalytic cycle of haloalkane dehalogenases. Here we describe experimentally and computationally the process of release of a halide anion from the buried active site of the haloalkane dehalogenase LinB. Using stopped-flow fluorescence analysis and umbrella sampling free energy calculations, we show that the anion binding is ion-specific and follow

Background: The free PSA fraction in serum of patients with various prostatic disorders is essentially unreactive with the anti-proteases in blood. Recently reported data show that it is likely to consist of a mixture of proPSA, internally cleaved PSA forms, and possibly other uncharacterized forms. Currently there are no specific methods available to measure the different free PSA subfractions an

10 juni 2026 14:00 till 15:00 | Event We are pleased to welcome Dr. Jonathan West from University of Southampton, UK, as the next speaker in the MAX4Life Talk Series on June 10. The MAX4Life series highlights innovative and impactful Life Science research through engaging one-hour long talks, followed by Q&A and informal mingling with the MAX IV community. Dr. West will be discussing microfluidic

https://www.lu.se/evenemang/max4life-talk-microfluidics-resolving-protein-dynamics-dr-jonathan-west - 2026-07-14

Objective: The aim of this study was to evaluate the utilization and impact of emergency computed tomography (CT) on the management of renal colic, focusing on treatment decisions, time to treatment and the subsequent need for additional emergency department (ED) visits.Materials and methods: Retrospective analysis of patient visits to the ED in Helsingborg with a diagnosis of urolithiasis (ICD co

Most models to predict biochemical recurrence (BCR) of prostate cancer use pretreatment serum prostate-specific antigen (PSA), clinical stage and prostate biopsy Gleason grade. We investigated whether human glandular kallikrein 2 (hK2) and free prostate-specific antigen (fPSA) measured in pretreatment serum enhance prediction. We retrospectively measured total PSA (tPSA), fPSA and hK2 in preoperat

Internet use by older-adults in rural and urban settings in Sweden - results from the SNAC study Berner J, Rennemark M, Jogréus C, Anderberg, P, Sköldunger A, Wahlberg M, Elmståhl S, Berglund J. Health Informatics Journal. 2014 Feb 24 Äldre (65+) börjar använda internet mera, men det har visat sig att det fortfarande finns många som inte gör det. Internetanvändning och att kunna använda informatio

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2014_internet-use-by-older-adults_bernerj.pdf - 2026-07-13

Sammanfattning av internetanvändning hos äldre, av J Berner et al., 2014 Internet use by older-adults in rural and urban settings in Sweden - results from the SNAC study Berner J, Rennemark M, Jogréus C, Anderberg, P, Sköldunger A, Wahlberg M, Elmståhl S, Berglund J. Health Informatics Journal. 2014 Feb 24 Äldre (65+) börjar använda internet mera, men det har visat sig att det fortfarande finns må

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2014_internet-use-by-older-adults_bernerj_tg.pdf - 2026-07-13

We developed a simple one-step dual-label immunoassay for simultaneous measurement of the free, noncomplexed form of prostate-specific antigen (PSA) and total PSA. The assay is based on time-resolved fluorescence and includes a stable fluorescent chelate of Eu to label a monoclonal antibody (mAb) that detects only free PSA, whereas a second mAb labeled with a fluorescent chelate of Tb provides equ

The antibody microarrays have become widespread, but their use for quantitative analyses in clinical samples has not yet been established. We investigated an immunoassay based on nanoporous silicon antibody microarrays for quantification of total prostate-specific-antigen (PSA) in 80 clinical plasma samples, and provide quantitative data from a duplex microarray assay that simultaneously quantifie

A flow immunodetection system with high sample throughput capacity is described for the screening of various analytes. The immunochemical detection principle is based on the chromatographic separation of the formed immunocomplex (AbAg or AbAg*) and the free antigen (Ag) by a restricted access (RA) column, utilising size-exclusion and reversed-phase mechanism. A fluorescein labelled analyte (Ag*) w

SUMMARY: Modern bioimaging and related areas such as sensor technology have undergone tremendous development over the last few years. As a result, contemporary imaging techniques, particularly electron microscopy (EM) and light sheet microscopy, can frequently generate datasets attaining sizes of several terabytes (TB). As a consequence, even seemingly simple data operations such as cropping, chro

A rapid method for the determination of the sum of free desmosine and isodesmosine in human plasma and urine is described. Efficient sample clean-up prior to LC-MS/MS analysis is mandatory for detection of free desmosines in plasma samples. The combination of ultra-filtration and a two-step solid phase extraction minimizes the sample complexity and ion suppression effects. The flow through from th

Letter of invitation in order to obtain visa to Sweden 2 Letter of invitation in order to obtain visa to Sweden The Department of XXXX at Lund University in Sweden hereby invites den sökandes fullständiga namn (enligt pass) den sökandes födelsedatum den sökandes passnummer XXXX (namn) is going to be visiting Sweden (for less than 90 days) in order to varför . Beskriv besöket, vad vederbörande ska

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2025-12/Mall%20Letter%20of%20Invitation%20Visum%20template%20240520.doc - 2026-07-13

Purpose: We investigated the value of serum measurements for glandular kallikrein 2 (hK2), and free (f) and total (t) prostate specific antigen (PSA) in a second round of biannual screening for prostate cancer. Materials and Methods: In 1995 to 1996, 5,853 of 9,811 randomly selected men in Goteborg, Sweden 50 to 66 years old had PSA measurements. Of 660 men 611 with tPSA 3 ng/ml or greater underwe

Deadlines and general information about applications to the Master of Fine Arts Programme in Artistic Research at Malmö Art Academy Deadline 1 March 2023 for applications including Submitted application at https://www.universityadmissions.se Double check that ALL your relevant grades are uploaded here.   Uploading of research proposal in the Malmö Art Academy application portal Register at https:/

https://www.khm.lu.se/anvisningar-masterprogrammet-i-fri-konst-med-inriktning-mot-forskningsforberedande-studier - 2026-07-13

Abstract Biocatalysis is considered as benign and efficient alternative to chemical catalysis for organic syntheses. Lipases are the most versatile biological catalysts implemented so far with great potential for production of different chemicals and materials in non-conventional reaction media. This thesis presents investigations on lipase catalyzed esterification and transesterification reaction

The capacity to get rid of excess heat produced during hard work is a possible constraint on parental effort during reproduction [heat dissipation limit (HDL) theory]. We released hard-working blue tits (Cyanistes caeruleus) from this constraint by experimentally removing ventral plumage. We then assessed whether this changed their reproductive effort (feeding rate and nestling size) and levels ofThe capacity to get rid of excess heat produced during hard work is a possible constraint on parental effort during reproduction [heat dissipation limit (HDL) theory]. We released hard-working blue tits (Cyanistes caeruleus) from this constraint by experimentally removing ventral plumage. We then assessed whether this changed their reproductive effort (feeding rate and nestling size) and levels of

This masters thesis deals with mathematical signal detection in the field of NQR, Nuclear Quadrapole Resonance, which is a non-invasive spectroscopic technique used to identify specific substances. The thesis has two main focuses, where the first is to propose novel methods for parameter estimation, especially for identification of unknown signals. These extend the existing Capon and APES methods