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Background: We previously found differences in total concentrations of tissue inhibitor of metalloproteinases 1 (TIMP-1) in plasma from donors and cancer patients. Because TIMP-1 can exist in more than one molecular form, a new immunoassay to specifically detect free TIMP-1 was developed and concentrations were determined in plasma from healthy donors and colorectal cancer (CRC) patients. Methods:
Selenium-based selenyl free radicals are chemical entities that may be involved in a range of biochemical processes. We report the first X-ray spectroscopic observation of a selenyl radical species generated photochemically by X-ray irradiation of low-temperature solutions of l-selenocysteine. We have employed high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) a
Prostate-specific antigen (PSA) is a serine protease belonging to the human glandular kallikrein gene family [1–3]. The expression of PSA is mainly androgen dependent, and the detection of very high expression levels is restricted to the prostate tissue, but extraprostatic production at much lower levels has been demonstrated in several other tissues such as normal and malignant breast epithelium,
A free port for art is a location in a country with purpose-built art facilities where imported works of art may be stored without taxes such as value added tax (VAT), goods and services tax (GST), consumption tax, transaction taxes and customs duties. As long as the art does not leave the free port, such taxes are not imposed, hence the word “free”. These free ports could be regarded as special t
In this paper, for any homogeneous system of agents with linear continuous time dynamics, we formulate an optimal control problem. In this problem a convex cost functional of the control signals of the agents shall be minimized, while the outputs of the agents shall coincide at some given finite time. This is an instance of the rendezvous or finite time consensus problem. We solve this problem wit
Humanity is facing one of the greatest challenges ever. Climate change and global warming is a great risk and our consumption and dependency of fossil fuel are important causes of this accelerating issue. My thesis aims to design an entry for the professional debate about what urban areas in a fossil free future might be like. I’m investigating how an urban environment that requires as little tra
We present exact algorithms with exponential running times for variants of n-element set cover problems, based on divide-and-conquer and on inclusion exclusion characterizations. We show that the Exact Satisfiability problem of size l with m clauses can be solved in time 2(m)l(O(1)) and polynomial space. The same bounds hold for counting the number of solutions. As a special case, we can count the
We present exact algorithms with exponential running times for variants of n-element set cover problems, based on divide-and-conquer and on inclusion-exclusion characterisations. We show that the Exact Satisfiability problem of size 1 with m clauses can be solved in time 2(m)l(O(1)) and polynomial space. The same bounds hold for counting the number of solutions. As a special case, we can count the
There are arguments around the nature and boundaries of the moral domain, with this current paper aiming to delineate one of these arguments. With a basis in George Sher's (2021) discussion of cognitions (beliefs, fantasies, attitudes and some thoughts), the paper defends the notion that they are, in fact, morally relevant. By combining the logic of truth-aptness with the phenomenology of agen
Scandinavian Relative Clause Extractions Apparent restrictions ∗ Fredrik Heinat & Anna-Lena Wiklund Linnaeus University & Lund University Abstract This brief article investigates the restrictions on Mainland Scandinavian relative clause extraction that have figured in the literature on island constraints. The con- clusion is that none of these restrictions can be regarded as constraints on relativ
https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Wiklund-Heinat_01.pdf - 2026-07-09
Drupal offers a wide range of possibilities for creating web forms, but it is also a large and complex tool. For example, you can create web forms to conduct surveys, collect expressions of interest for a conference, or as a way for visitors to get in touch with your organisation – but to create effective web forms, you need a basic understanding of how web forms in Drupal work.Web forms and web f
https://www.webbpublicering.lu.se/guides-english/web-form - 2026-07-09
We compare free energy calculations for the methyl transfer reaction catalyzed by catechol O-methyltransferase using the quantum mechanical/molecular mechanical free energy method with implicit and explicit solvents. An analogous methylation reaction in a solution is also studied. For the explicit solvent model, we use the three-point transferable intermolecular potential model, and for the implic
PURPOSE: The low molecular mass and short half-life of free (f) prostate specific antigen (PSA) implies elimination from blood by glomerular filtration. In addition, patients with terminal renal failure have increased fPSA in serum but there have been sparse data reported on the rates and pathways of elimination of PSA complexes and human kallikrein 2 (hK2). We studied glomerular filtration depend
