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BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro

The thawing and subsequent decomposition of large stocks of soil organic carbon (SOC) currently stored in the northern circumpolar permafrost region are projected to result in a ‘positive’ feedback on global warming. The magnitude of this feedback can only be assessed with improved knowledge about the total size and geographic distribution of the permafrost SOC pool. This study investigates SOC st

Importance: Lack of arachidonic acid (AA) and docosahexaenoic acid (DHA) after extremely preterm birth may contribute to preterm morbidity, including retinopathy of prematurity (ROP).Objective: To determine whether enteral supplementation with fatty acids from birth to 40 weeks' postmenstrual age reduces ROP in extremely preterm infants.Design, Setting, and Participants: The Mega Donna Mega trial,

Prefetching is a well known concept for CPUs but for GPUs it is fairly unexplored. The memory management of a GPU plays a crucial role in its performance, and cache prefetching has the potential to lower the overall latency. This thesis compares different types of prefetching methods for GPUs and remaking some CPU prefetchers to fit the GPU architecture. All these prefetchers were then put inside

The following study consists of a qualitative analysis based on six heterosexual girls' stories about the way out of their violent relationship. The purpose of the study was to gain an increased understanding of the six girls' leaving processes and which factors led to the final breakup. The empirical material was based on six podcast episodes where the girls talked about their experience

Utredningshemmet in Hässleholm, Sweden, is a special residential home for acute management and investigative evaluation of juvenile delinquents. Utredningshemmet has, since 1991, used an investigative model, which is based on systems theory. The investigative work is done in close co-operation with social workers, youths and their parents. This study takes into account the youths, who have had a

(1) Background: To identify reasons for the persistence of surgical ligation of the patent ductus arteriosus (PDA) in premature infants after the 2019 Food and Drug Administration (FDA) approval of transcatheter device closure; (2) Methods: We performed a 10-year (2014–2023) single-institution retrospective study of premature infants (<37 weeks) and compared clinical characteristics and neonatal m

The COP 15 of the UN Convention on Biological Diversity emphasised the need to monitor, evaluate, and disclose the risks and dependencies of financial institutions on biodiversity. In the light of this context, our paper focuses specifically on banks and is framed by the following overarching question: to what extent have banks identified, integrated, measured, and disclosed their dependency and e

The important role of fire in regulating vegetation community composition and contributions to emissions of greenhouse gases and aerosols make it a critical component of dynamic global vegetation models and Earth system models. Over two decades of development, a wide variety of model structures and mechanisms have been designed and incorporated into global fire models, which have been linked to di

Atmospheric measurements show that emissions of hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons are now the primary drivers of the positive growth in synthetic greenhouse gas (SGHG) radiative forcing. We infer recent SGHG emissions and examine the impact of future emissions scenarios, with a particular focus on proposals to reduce HFC use under the Montreal Protocol. If these proposals are

Globally, the lifespan of populations increases but the healthspan is lagging behind. Previous research showed that survival into extreme ages (longevity) clusters in families as illustrated by the increasing lifespan of study participants with each additional long-lived family member. Here we investigate whether the healthspan in such families follows a similar quantitative pattern using three-ge

A new aromatic pair, 2-hydroxy-6-methoxybenzamide/1-methylpyrrole at the terminal position of hairpin polyamides has been designed for distinguishing T·A from A·T base pairs and both from G·C/C·G in the minor groove of DNA. Four eight-ring hairpin polyamides with benzamide (Bz), 2-hydroxybenzamide (Hb-1), 2-hydroxy-6-methylbenzamide (Hb-2), and 2-hydroxy-6-methoxybenzamide (Hb-3) at the N-terminal

In this study, the photoelectrochemical behavior of electrodeposited FeNiOOH/Fe2O3/graphene nanohybrid electrodes is investigated, which has precisely controlled structure and composition. The photoelectrode assembly is designed in a bioinspired manner where each component has its own function: Fe2O3 is responsible for the absorption of light, the graphene framework for proper charge carrier trans

Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised to affect type 1 diabetes (T1D) and rheumatoid arthritis (RA). However, maternal effects may also play a role. By using a mixed model that is able to simultaneously consider all kinds of POEs, the importance of POEs for the development of T1D and RA was investigated in a variance components analysis. The analys

PEDS_20171305 1..3 Article Hagopian et al Co-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity 2017 https://doi.org/10.1542/peds.2017-1305 5 Pediatrics ROUGH GALLEY PROOF November 2017 140 Co-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity William Hagopian, MD, PhD, a Hye-Seung Lee, PhD, b Edwin Liu, MD, c Marian Rewers, MD, MPH, c Jin-Xiong She, PhD, d Anette-G. Ziegler,

https://www.teddy.lu.se/sites/teddy.lu.se/files/11152017_679_79_mp56_hagopian_pediatrics_2017.pdf - 2026-06-27