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In order to study the influence of the hypothalamic-pituitary-adrenal axis on the levels of endogenous digitalis-like substances (EDLS) in plasma and urine, eight healthy subjects (25-40 years old) were given dexamethasone 1 mg orally and tetracosactide (an ACTH analog) 0.25 mg i.v., on separate occasions. The circulating levels of EDLS, TSH, PRL and AVP following administration of either test dru
Conformational changes and stability of interacting double-stranded DNA chains under high hydrostatic pressure in biological systems are striking topics of importance to study several biomolecular phenomena. For example, to unravel the physiological conditions at which life might occur and to ensure the right functionality of the biochemical processes into the cell under extreme thermodynamic cond
Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more
Our book has taken a distinctive, policy-oriented approach to IGR in analysing both specific crisis-driven problems and new, longer-term, and emerging policy issues confronting European governments. We have explored the shifting balances of power within IGR systems focused on the challenges of vertical and horizontal coordination within cross-country, comparative perspectives. In order to position
Cardiovascular (CV) morbidity and mortality is high in patients with chronic kidney disease (CKD). Most patients reveal a high prevalence of CV risk factors such as diabetes or arterial hypertension and many have manifest cardiovascular disease (CVD), such as coronary artery disease and chronic heart failure with an increased risk of clinical events including sudden cardiac death. Diabetes mellitu
When discussing choice of methodology in evaluation studies, it is wise to reflect upon organizational considerations concerning contracting, conducting and utilization. Based upon research conducted among social workers in Sweden this paper focuses upon possibilities and problems in knowledge dissemination and usage. Powerful institutions in Sweden are now encouraging knowledge development of soc
This thesis investigates how reliance on ONVIF certification, a global interoperability standard in the network video industry, influences how a large technology company organises its internal organisational structures, roles, responsibilities and resource allocation. Technical standards such as ONVIF, with adherence validated through certification processes, are widely used to promote interoperab
Popular Abstract in Swedish Syftet med denna avhandling är att utforska fenomenet vetenskapligt kritiskt tänkande, när det gäller dess olika innebörder, villkor och utveckling. Kritiskt tänkande studeras genom att analysera olika filosofiska och pedagogiska texter, utifrån ett hermeneutiskt-fenomenologiskt perspektiv. Avhandlingen som är skriven på engelska erbjuder läsaren en inblick i hur min egThe purpose of this thesis is to explore the phenomenon of critical thinking in scholarship as regards its meanings, conditions, and development using a hermeneutic-phenomenological approach. This exploration takes its departure in ancient Greece, following a historical movement of the phenomenon up to present day perspectives on critical thinking, revealing a range of different meanings and condi
We analyzed seasonal flu vaccination rates among the Italian population suffering from Chronic Obstructive Pulmonary Disease (COPD) in order to identify socio-demographic and clinical determinants for vaccination. We used data from the survey "Health and health care use in Italy", which interviewed 5,935 persons (age 15 - 102 years) suffering from COPD in the period 2004-2005. For each respondent,
A dual-band CMOS front-end was designed and fabricated in a 0.18 μm CMOS process. The front-end employs a common-gate low noise amplifier (LNA) with capacitive cross coupling (CCC) technique and a passive mixer. The band selection is performed by switching a capacitor in and out of the LNA load, changing the resonance frequency between 2.2GHz and 4.0GHz. The measured noise figure is below 3.5dB fo
Popular Abstract in English My dissertation is a Swedish history of ideas 1965-2010 as expressed in the best-selling and most influential Swedish police novels and films. The title is "The Cop in the Twilight Land. Swedish Police Narratives in Novels and Film 1965-2010". Here I elaborate on the analysis briefly treated in the essay "Skymningslandet" ("Twilight Land") in the anthology "SolskenslandThe dissertation "The Cop in the Twilight Land: Swedish Police Narratives 1965-2010" considers Swedish culture and ideas in the period 1965-2010 as expressed in detective fiction and film in the tradition of Maj Sjöwall and Per Wahlöö. It takes the Swedish police narrative tradition to be part and parcel of the European history of ideas and culture; a history that necessarily comprises America, by
Popular Abstract in Swedish The overall interest pursued in this thesis is how the former socialist economies of Central and Eastern Europe can build strong and dynamic systems of innovation. The purpose of the thesis is to investigate the dynamics and evolution of the telecommunications system of innovation in Estonia from the late Soviet period to Estonia's EU accession, and to provide an in-depThe overall interest pursued in this thesis is how the former socialist economies of Central and Eastern Europe can build strong and dynamic systems of innovation. The purpose of the thesis is to investigate the dynamics and evolution of the telecommunications system of innovation in Estonia from the late Soviet period to Estonia's EU accession, and to provide an in-depth explanation of how innova
BACKGROUND: Traditionally oocytes have been exposed to sperm overnight, for 16-20 h. This long period of co-incubation, however, has been shown to create problems with high levels of reactive oxygen species (ROS), which may affect embryo viability and cause hardening of the zona pellucida. Recently, a positive effect of reducing the co-incubation time to 90-120 min was reported. The objective of t
Background: Lung densitometry is an effective method to assess overall progression of emphysema, but generally the location of the progression is not estimated. We hypothesized that progression of emphysema is the result of extension from affected areas toward less affected areas in the lung. To test this hypothesis, a method was developed to assess emphysema severity at different levels in the lu
Popular Abstract in Swedish Förändring av kroppsprotein hos cancerpatienter under behandling Bakgrund Det är välkänt att patienter med cancer ofta drabbas av nedsatt aptit, viktminskning, orkeslöshet och ämnesomsättningsrubbningar under sin sjukdom. Denna samlade symptombild kallas kakexi. Detta tillstånd minskar toleransen för olika behandlingar, som cytostatika- och strålbehandling, försämrar The purpose of this study was to investigate how total body protein and its fraction of body weight (body protein fraction) change in cancer patients during different anti-tumor treatments, and to see if these changes have any clinical significance in the form of prognostic value or correlation with disease course and tumor response. In 84 patients, 28 with lung cancer, 24 with gastrointestinal t
Research streams in industrial- and service marketing have announced the increasing intangibility and servitization of business exchanges and as a consequence their more interactive nature. Even though, early interaction models support the idea of exchanges as social interaction processes, little is known about this social, individual level between companies. The study therefore aims to increase t
OBJECTIVES: The aim of this study was to investigate whether job strain, psychological demands, and decision latitude are independent determinants of disability pension rates over a 12-year follow-up period. METHODS: We studied 3,181 men and 3,359 women, all middle-aged and working at least 30 h per week, recruited from the general population of Malmö, Sweden, in 1992. The participation rate was
