Search results

In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic

Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves

Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease driven by persistent fibroblast activation, abnormal epithelial to mesenchymal signaling and excessive extracellular matrix (ECM) remodeling. Better pre-clinical models are needed to reproduce these processes and to support antifibrotic drug development. This thesis tested whether an in vitro co-culture model

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with asthma and healthy controls under identical conditions. Mast cells were cultured from peripheral blood from twelve patients with an objectively confir

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Introduction: Subanesthetic doses of ketamine are a promising novel treatment for suicidality; however, the evidence for predictive biomarkers is sparse. Recently, measures of complexity, including Lempel–Ziv complexity (LZC) and multiscale entropy (MSE), have been implicated in ketamine's therapeutic action. We evaluated electroencephalogram (EEG)-derived LZC and MSE differences between responder

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Artistic Research - Workshop in Theory and Practice Malmö, 22-23 January 2016”People will observe you, in order to investigate how well you have observed” Bertolt BrechtWhat is the role of observation and imitation in the actor’s work, and how does this relate to the artist’s individual experience and self-expression? What is the role of imitation and quotation in theoretical reflection, and how d

https://www.thm.lu.se/observe-imitate-be-yourself-2 - 2026-07-05

How can artistic creative practice be combined with ethnological cultural analysis? A process based on practices of art probing is proposed and related to discussions about museum imaginaries, digital cultures and sensory aspects of ethnography. The point of departure for the discussion is the audiovisual performance Possible Worlds.

In the light of a world-wide shortage of helium-3 (3He) a development of novel neutron detector systems (NDS) is necessary. This requires mathematical descriptions of the neutron scattering process in thin films. In this bachelor thesis our aim is to make a probabilistic model of the scattering of a single neutron travelling through a thin film, with main focus on the first scatter occurrence. The

Car prevalence in society has a negative effect on both local and global environments. One way to tackle these problems is to restrict car traffic in city centres, this comes not only with effects on the environment. How car free zones can affect retail in cities is examined in this study. The study takes place in ten retail shops in the city centre of Lund along three streets. Customers are aske

Ownership and finance are crucial for governance, decision-making, and strategic objectives in entrepreneurial ventures. They affect how firms raise capital, scale, and navigate risks, ultimately impacting both success and sustainability. By examining ownership structures in relation to emerging financing models like equity crowdfunding, ICOs, and blockchain-based solutions, our research provides

https://www.lusem.lu.se/organisation/research-centres/sten-k-johnson-centre-entrepreneurship/research-sten-k-johnson-centre-entrepreneurship/entrepreneurial-ownership-and-new-venture-finance - 2026-07-05

Teman för forskning Under REAL:s tematiska paraply — cirkularitet, digital omvandling samt kompetens- och organisationsutveckling — antar vi ett omfattande och integrerat tillvägagångssätt för att förstå och forma framtiden för detaljhandel och logistik. Tillsammans tar dessa teman upp viktiga utmaningar och möjligheter i sektorn, med det övergripande målet att bidra till ett mer hållbart och effe

https://www.real.lu.se/forskning - 2026-07-05