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Title: Direct Material Safety Stock Standard Authors: Oscar Gustavsson, Oskar Strömberg Supervisors: Gustaf Lilja, IKEA Industry Eva Berg, Division of Industrial management and logistics, Lund University Contribution: This thesis has been a complete elaboration between the two authors. Each author has been involved in every part of the process. Background: In a time when everything is available at
When organic material is deposited at a landfill it is decomposed over time by microorganisms to form a gas mixture consisting of mainly methane, carbon dioxide and nitrogen called landfill gas. To limit the environmental impact from this gas there is a requirement in Sweden today that all landfills which have accepted or are accepting organic material to be equipped with a gas collection system a
In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. Such Hb-based products have used cell-free Hb purified from human, bovine, invertebrate, or recombinant sources to create hemoglobin-based oxygen carriers (HBOCs). However, administ
Varje cell har ett membran som skapar en gräns mot omvärlden och skyddarcellen. Men cellen måste alltjämt utbyta viktiga molekyler med omvärlden för attöverleva. Därför finns specialiserade proteiner, som sitter i membranen och utgörportar i denna barriär. Denna avhandling fokuserar på två membranproteiner, enprotonpump och en jonkanal.Varje dag i våra liv använder vi hjärnan, muskler och hjärtat.NADH:quinone oxidoreductase (Complex I) is the first enzyme of the respiratory chain and is involved in energy conservation generating an electro-chemical gradient across a membrane. The enzyme can be divided into a membrane spanning domain and a hydrophilic domain, which protrudes from the membrane. In the hydrophilic domain electrons from NADH oxidation are transported via a wire of iron-sulfur
Popular Abstract in Swedish Bilsäten har genomgått en kontinuerlig utveckling ända sedan de först beskrevs år 1885. På den tiden kunde man läsa om vadderade läderbänkar, monterade på stora fjädrar, fastsatta i chassit på ”hästlösa vagnar”. När polyuretanskum först började tillverkas på 1950-talet introducerades de snabbt i bilsätena och dessa genomgick stora förbättringar. Skummen utgör idag en stAutomotive seating has been under continous development since it was described for the first time in 1885. At that time one could read about a “padded leather bench seat sitting on springs mounted directly to the frame of a horse-less carriage”. With the development of flexible polyurethane foam in 1950-1960 the seats were considerably improved and the traditional springs were eventually replaced
This thesis is a study of social life, addressing issues concerning how and by what means people meet in urban public space. The main aim of this thesis is to is to investigate how certain artefacts and architectural features support the formation and temporal stabilisation of heterogeneous clusters and collectives, and thus, in order to the development of conceptual tools that can contribute to a
Background: Emerging evidence suggests that artificial intelligence (AI) can increase cancer detection in mammography screening while reducing screen-reading workload, but further understanding of the clinical impact is needed. Methods: In this randomised, controlled, parallel-group, non-inferiority, single-blinded, screening-accuracy study, done within the Swedish national screening programme, wo
Vegetation is the major source of volatile organic compounds (VOCs) in the atmosphere, which affect both air quality and climate. Long-term ecosystem-level data on biogenic VOC (BVOC) emissions, however, are limited. This is especially true regarding the impacts of landscape-scale disturbances like clear-cutting on the short-term and longer seasonal-scale emissions of boreal forests, particularly
Background: The absence of Epithelial Membrane Protein 3 (EMP3) on red blood cells (RBCs) underlies the MAM-negative (MAM−) phenotype. EMP3 is a ubiquitous protein found at low levels in most tissues but with higher expression in hematopoietic cells. Low levels of CD44 are a signature of MAM− RBCs due its proposed physical interaction with EMP3, indicating that EMP3 stabilises CD44 in the membrane
This report consists of five tasks which were designed to gain an in-depth and broad understanding of the state-of-the-art on research, policy and practice on integration of refugees and host community relations. This was undertaken to form a foundation upon which to build Work Packages focusing on the field work (WP 3 and 4), the development of a refugee and host community toolbox (WP5 and 6) and
Importance: Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known. Objective: To evaluate whether the levels and trajectories of blood p-tau, Aβ42, and Aβ40 following cardiac a
Background: Posterior cortical atrophy is a rare syndrome characterised by early, prominent, and progressive impairment in visuoperceptual and visuospatial processing. The disorder has been associated with underlying neuropathological features of Alzheimer's disease, but large-scale biomarker and neuropathological studies are scarce. We aimed to describe demographic, clinical, biomarker, and neuro
Popular Abstract in Swedish Polymerelektrolytbränslecellen utmärker sig som en framtida effektiv och miljövänlig kraftkälla för bland annat fordon. Den bakomliggande teknologin är dock komplex och grundar sig till stor del på material och komponenter som kräver ytterliggare utveckling. En av de största hindren för bränslecellsteknologins utveckling är kravet på nya, långlivade och billiga polymermThe proton exchange membrane fuel cell (PEMFC) is currently emerging as an efficient and environmentally friendly power source. The technology is very complex and relies ultimately on materials and components which need further development. One of the major hurdles for advancing the PEMFC technology is currently the demand for new durable low-cost polymeric membranes that will allow fuel cell oper
The glymphatic system is a brain-wide solute clearance system that has developed in the brain to clear metabolic waste during sleep. This clearance is mediated by advective fluxes of cerebrospinal fluid (CSF) along perivascular spaces (PVS) and through the brain. The movement of CSF from the PVS and through the brain is dependent on the polarised expression of aquaporin-4 (AQP4) at astrocyte endfe
BACKGROUND: Plasma biomarkers associated with Alzheimer's disease could improve prognostic assessment for people with Down syndrome in both clinical practice and research settings. We aimed to identify the plasma biomarkers that most accurately predict longitudinal changes in Alzheimer's disease-related pathology and cognitive functioning in individuals with Down syndrome.METHODS: This longitudina
Controlling the surface morphology and chemical interaction is necessary for the development of advanced quantummaterials, particularly in low-dimensional systems. As the research increasingly focuses on miniature and nanoscaletechnologies, a fundamental understanding of localized or interface states becomes essential for successful integrationinto functional devices. This thesis investigates atom
BackgroundIbrutinib, a Bruton tyrosine kinase inhibitor, prolongs progression-free survival when added to immunochemotherapy as first line treatment. The ENRICH trial compared the chemotherapy-free combination of ibrutinib and the anti-CD20 antibody rituximab (ibrutinib–rituximab) with standard immunochemotherapy (R-CHOP [rituximab–cyclophosphamide, doxorubicin, vincristine, and prednisolone] or b
