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Objectives. The EGFR is expressed in malignant ovarian tumor tissue, and tissue content of EGFR has been directly associated with poor prognosis in patients with ovarian cancer. The uPA system plays a role in pericellular proteolysis, cell migration, invasion, and is over-expressed in ovarian cancer. This study explored the effects of EGF on uPAR expression in the ovarian cancer cell line OVCAR-3.

Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. Since majority of the mitochondrial genes are encoded by the nuclear genome, a tightly regulated and coordinated nuclear-mitochond

Professor Kontaktinformation E-post: sven [dot] bjerstedt [at] thm [dot] lu [dot] se Telefon: +46 70 833 92 33 Mobil: +46 70 833 92 33Organisation Lärare (Teaterhögskolan) Besöksadress: Rönngatan 6, Malmö WebbplatsSven Bjerstedts profil i Lunds universitets forskningsportalAndra roller Docent Lärare (Teaterhögskolan) Ansvarig för doktorandutbildningen Lärare (Teaterhögskolan) Publikationer Visar a

https://www.thm.lu.se/sven-bjerstedt-0 - 2026-07-09

Enligt principen jura novit curia behöver inte svenska rättsregler åberopas eller bevisföras av part i svensk domstol. Istället ankommer det på domstolen att ex officio söka reda på och tillämpa de rättsregel som domstolen finner tillämpliga på tvisten (35 kap. 2 § st. 2 rättegångsbalken). Utöver denna utredningsskyldighet innebär principen jura novit curia även ett rättstillämpningsmonopol som tiAccording to the principle iura novit curia, parties in a Swedish court do not have a burden of pleading or proof for the content of Swedish law, nor is the court bound by the parties’ instructions or opinions concerning the application of the law. The court must consider all relevant legal rules and ex officio apply the rule of law deemed applicable to the dispute. This last part does not, howeve

Allvarlig brottslighet som begås inom kriminella nätverk har ökat drastiskt under senare år. Skjutningar och sprängningar har blivit alltmer förekommande och nu diskuteras även finansierandet av skjutvåldet genom narkotika-, smugglings- och ekonomisk brottslighet i politiska debatter. Hur man ska komma till rätta med problemet, med hänsyn till förbättrade tekniska förutsättningar och tystnadskultuSerious crimes committed within criminal networks have increased drastically in recent years. Shootings and explosions are unusually often occurring in Sweden and now the financing of this deadly violence by drug, smuggling and financial crimes is also discussed in political debates. How to effectively deal with the problem, despite improved technology and a culture of silence in criminal gangs, i

Den 1 januari 2022 fick 2 kap. brottsbalken, innehållandes regler om svensk straffrättslig jurisdiktion, en helt ny lydelse. Reformen innebar förändringar av jurisdiktionsreglernas innehåll så väl som struktur, och hade delvis som mål att närmare anpassa den svenska rätten till folkrätten. Följande arbete syftar till att utvärdera huruvida den nya jurisdiktionsrätten uppnår denna målsättning. För On 1 January 2022 an extensive reform of Chapter 2 of the Swedish Criminal Code, which contains rules pertaining to criminal jurisdiction, entered into force. This reform carried with it major changes in both structure and material content and was partially intended to align Swedish law more closely with international law on the matter of criminal jurisdiction. The following paper aims to evaluate

A claimant is not prevented from assigning his claim to a third party during ongoing arbitration proceedings. The legal relationship in dispute in the proceedings can thus be transferred to someone other than the original parties by means of so called singular succession. For several of the issues raised by singular succession in arbitration, there are no specific statements in the generally accep

The purpose of this essay is to investigate how Sweden got free abortion by examining the arguments made during the parliamentary debate in 1974, which concerned the legislation of free abortion. This is done using a legal historical method and the material that has been used consists mainly of the protocols from the debate. To put the debate in its context the thesis also gives an overview over

Pacta sunt servanda - The fundamental principle of Swedish law is that agreements must be kept. This means that a buyer can only exceptionally be released from the obligation to perform according to the agreement. This essay aims to investigate the possibilities a buyer has to be released from liability when he has undertaken to perform a certain performance and subsequently been prevented from fu

This thesis investigates the intersection of urban greening and multispecies justice from a more-than-human (MTH) perspective in Mexico City (CDMX). The study addresses a critical gap in existing research, which predominantly focuses on the human-centric implications of urban greening, such as gentrification and human well-being, while neglecting the needs and well-being of non-human life forms. B

De första universiteten i Europa grundades i en tid då samhället var strikt hierarkiskt. Det bestod av sammanslutningar, så kallade korporationer, med olika rättigheter och skyldigheter sinsemellan. Universitetet utvecklades till att bli en sådan korporation. Efterhand tillerkändes vissa korporationer privilegier, inledningsvis av den andliga makten och sedan av den värdsliga. Ett av de privilegieThe first universities in Europe were founded during a time when society was strictly hierarchical. It consisted of various associations, so called corporations, each with their own different rights and obligations. The university developed to become such a corporation. Subsequently, certain privileges were granted certain corporations, at first by the spiritual power and later by the worldly powe

The Jurassic sandstones around Höör and Vittseröd in central Skåne, southern-most Sweden are almost unique for Sweden and have been subjected to quarrying for at least 1000 years to produce millstones and building blocks for major buildings including the Lund cathedral. In the present study, the bryophyte flora of 17 such old or ancient sandstone quarries is investigated and described. A total of

Induced polarization (IP) is an acknowledged method in ore exploration and can be applied to evaluate the metal content in dumps containing the residues of ore processing facilities. Existing models explain the relationships between ore content and grain size of the ore particles with IP parameters. However, the models assume full water saturation of the ore containing samples, which is often not

Subcellular membrane systems are highly enriched in dolichol, whose role in organelle homeostasis and endosomal-lysosomal pathway remains largely unclear besides being involved in protein glycosylation. DHDDS encodes for the catalytic subunit (DHDDS) of the enzyme cis-prenyltransferase (cis-PTase), involved in dolichol biosynthesis and dolichol-dependent protein glycosylation in the endoplasmic re

Hepatitis B virus (HBV) infection remains a major public health threat in the Middle East and North Africa (MENA). Phylogenetic analysis of HBV can be helpful to study the putative transmission links and patterns of inter-country spread of the virus. The objectives of the current study were to analyze the HBV genotype/sub-genotype (SGT) distribution, reverse transcriptase (RT), and surface (S) gen

Svensk byggindustri är under förändring. Stora delar av produktionen läggs idag ut på entreprenad och byggföretag förlitar sig på underentreprenörer i större utsträckning än tidigare. Som en del av en global trend av kostnadsreducering inom byggindustrin, försöker byggföretag minimera antalet anställda hantverkare och istället utkontraktera arbete till underentreprenörer i strävan efter organisatoThe organisation of work in the Swedish building sector is changing due to increased subcontracting and the adoption of construction management. In this study, construction management refers to a specific subcontracting regime, in which contractors externalise all parts of the production process and organise work through subcontractors. Echoing global trends of cost-cutting, this externalisation b

Objectives: In this study, we aimed to assess the stratification ability of the Fracture and Mortality Risk Evaluation (FAME) index for reoperation, new fragility fracture, and mortality during one-year follow-up. Patients and methods: Between November 2018 and July 2019, a total of 94 consecutive hip fragility fracture patients from two centers (20 males, 74 females; mean age: 79.3±8.9 years; ran