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This second edition of the infrared microwindow atlas contains a collection of spectral mi- crowindows commonly used or recently suggested for ground-based, high resolution, infrared solar absoption spectroscopy. These solar observations are aimed at quantifying the abun- dance of trace species in the terrestrial atmosphere. A microwindow is a narrow spectral interval that allows to observe a spec
Phenotypic plasticity may enable organisms to optimize their phenotypes in environments that are heterogeneous over time or space. For example, inducible defenses are favored for prey populations faced with variable predation risk. We studied the impact of brook trout (Salvelinus fontinalis) on the development of defensive morphological characters in larvae of the mayfly, Drunella coloradensis, bo
Collagen XVI is a minor component of at least two different extracellular fibrillar networks of specialized regions of skin and cartilage. In skin, collagen XVI is integrated into particular fibrillin-rich microfibrils lacking an amorphous elastin core. In cartilage, collagen XVI is a component of small heterotypic D-banded fibrils, mainly occurring in the territorial matrix of chondrocytes. Here,
This thesis is based on six scientific papers providing different methods for coordinated inventory control in supply chains. The main focus is on supply chains in connection with distribution of products to customers. Two different problem areas are considered. One problem area concerns coordination by centralized optimization of local decision rules. It is assumed that the decision system is ce
The Nordic countries have a long tradition of large-scale biobanking and comprehensive, population-based health data registries linkable on unique personal identifiers, enabling follow-up studies spanning many decades. Joint Nordic biobank-based studies provide unique opportunities for longitudinal molecular epidemiological research. The purpose of the present paper is to describe the possibilitie
In the narrow offshore border zone between Germany and Denmark, 550 km of high-density 3.5-kHz subbottom seismic reflection profiles were recorded within a 70-km(2) area in order to reconstruct the seismic stratigraphy of late Pleistocene to early Holocene lacustrine and fluvial environments. Using detailed line drawings, seismic facies analyses and a hierarchy of bounding surfaces, a depositional
In the present thesis molecular genetic methods were used to address different biological and clinical aspects of Philadelphia (Ph) chromosome-positive leukemias and the BCR and ABL genes. In the first study, children with Ph-positive chronic myeloid leukemia (CML) were found to have essentially the same breakpoint locations in BCR as adults, a pattern which differs from the one seen in Ph-positiv
Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe
Popular Abstract in Swedish Atmosfäriskt nedfall är den största källan till miljögiftet PCB i sötvatten. I flertalet vattendrag, exempelvis Emån, fungererar också sediment som en källa. Ett pappersbruk i anslutning till Emån hade använt returpapper som innehöll PCB som råvara. PCB följde med utsläppen till ån och lagrades in i sedimenten. Miljögiftet läckte sedan ut långsamt till vattnet. Största Atmospheric deposition is one source of persistent pollutants such as polychlorinated biphenyls (PCB) in aquatic environments. Other point sources can also contribute to the PCB loadings in the water. In the Emån River, in southeast Sweden, contaminated sediment was a source of PCB, the largest deposits of it being found in a small lake connected with the river, Lake Järnsjön, the sediment of it c
Popular Abstract in Swedish Vi har studerat hur man kan använda immunsystemet för att behandla råttor med hjärntumör (maligna gliom). Eftersom råttor väldigt sällan utvecklar hjärntumörer, så måste vi injicera tumörceller i hjärnan själva. Om djuren inte får någon behandling dör de vanligen inom ca. 24 dagar. Får de däremot en injektion i buken eller under huden på benet med genmanipulerade tumörcMalignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. Because of the poor prognosis, several additional therapies have been investigated and are under development, such a
Water management tackles complexities within the interconnected social, political, economic and ecological systems across scales, while aiming to meet the needs of multiple stakeholders dependent on water. Many tensions and unsolved issues persist in water management regarding socio-political power structures, spatial scale, and relations between stakeholders who have different perceptions on prob
The development and the use of anibiotics since the second half of XX century really affected the approach on treatment and prevention of infectious diseases. Despite a lot of resources and energies has been invested on the research, antibiotics resistance is a growing phenomenon in the last years. Today this problem has become a real public health priority worldwide, not only for the important cl
This thesis is a propositional study, analysing to what extent conventional concepts of urban housing architecture require updating in response to increasingly progressive living patterns developing in Europe. The propositional design is a modular system including permanent housing for short-term accommodation - alongside a trail of public walkways - which inhabits, activates and connects a netwo
With the global population projected to reach eight billion by 2022, the world faces significant challenges associated with rapid urbanization. The migration of individuals from rural to urban areas in search of improved opportunities exacerbates the strain on resources, posing obstacles such as housing shortages, infrastructure demands, and food scarcity in growing cities. This thesis aims to add
The aim of our study is to understand how milk is represented online, more specifically on the Swedish web. We are interested in how information is being produced and distributed online, and also how networks of information are interconnected. We choose to examine milk because of the current controversies that have flourished online between a Swedish oat milk company and a Swedish milk organisatio
In developing countries across the world people are depending on rivers as a source of water for drinking, cooking and bathing. This is also the case in the Indonesian part of the island Borneo where this study was made. The largest river is the river Kapuas which, together with its tributaries, supplies the area with water. The hydrology of these rivers is changing and the quality of the water in
The ability of microgels to adsorb to the interface of emulsion oil droplets has previously beenn reported in the literature.1 The resulting emulsions carry the thermoresponsiveness of the adsorbed microgels, and can be destabilized on demand by increasing the temperature above the volume phase transition temperature of the microgels. This thesis describes the synthesis and characterization of cro
Gymnadenia conopsea s.l., the fragrant orchid is widely distributed over Europe and adjacent parts of Asia. It is frequently found in open grassland, woodland and rich fen habitats, particularly in calcareous regions. The species is characterized by a high variation in morphological and genetic characters including plant height, floral characters, flowering time, habitat preferences, allozymes and
