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Organisation_MR_Group PhD Students E Lind B Lampinen A Lundberg H Olsson M Novén* J Brabec E Olsson F Durmo* A Seidemo Post-docs/Other A Bibic* F Testud C Gustafsson* P Brynolfsson* M Andersen A Rydhög F Szczepankiewicz N Spotorno* D Barron* Undergrad Students/Other T Rumetshofer U Gasay YM Bruun O Haglund A Fingerhut T Rosholm Research Radiographers T Owman B Hansson M Simic* L Wennberg* Seniors

https://www.msf.lu.se/sites/msf.lu.se/files/190110_organisation_mr_group.pdf - 2026-07-20

Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

The principal aims of this thesis are to define suitable measures for safer pedestrian and cycle crossings on arterial roads, to implement these measures on a large scale and to acquire an insight into their effects on road users' safety, experiences, mobility and the environment, by creating a 30 km/h milieu at the above crossings. Two characteristically different types of measures, physical meas

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_c/Charlotta.txt - 2026-07-20

C:/Report_050125/REPORT.dvi Department of Mechanical Engineering Solid Mechanics ISRN LUTFD2/TFHF–05/5111–SE(1–156) EVALUATING THE 3DM MODEL - AN EXPERIMENTAL AND FINITE ELEMENT STUDY Master’s Dissertation by Oscar Elison and Lars Hansson Supervisors Johan Tryding, Tetra Pak Magnus Just, Tetra Pak Anders Harrysson, Div. of Solid Mechanics Matti Ristinmaa, Div. of Solid Mechanics Copyright c© 2005

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5111.pdf - 2026-07-20

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri