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From Genotypes of Immunoglobulin Constant Heavy G Chains (Fcγ) (GM) Genes (IGHG) to Phenotypes in Childhood Asthma.

Background: IgE-mediated allergy is associated with immunoglobulin heavy constant G chain (Fcγ) (GM) genes (IGHG) on chromosome 14q32.3. Investigation of the alternative GM allotypes of γ3, γ1 and γ2 chains has disclosed new structural and functional IgG subclasses and B-cell variants, with possible effects on childhood asthma. Objective: To investigate different IGHG (GM) gene complexes in a

Binding of monoclonal IgM rheumatoid factor to streptococci via the antibody combining site

Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on

Retoriska strider : Konkurrerande sanningar i dövvärlden

Popular Abstract in Swedish Under de senaste par decennierna har en specifik tolkning av döva och dövhet blivit alltmer etablerad på det ”officiella” dövområdet i Sverige, tillika anammat av såväl professionella som föräldrar till döva barn. Döva ska enligt detta synsätt hellre betraktas som tillhörande en kulturell och språklig minoritet än som handikappade. Medicinska strävanden att “laga defektIn the last couple of decades a particular interpretation of deaf and deafness has been established in ‘official’ arenas in Sweden. Deaf individuals, according to this view, should not be seen as disabled, but rather as belonging to a cultural and linguistic minority. Such views find expression in a locally established usage that may be termed a deaf culture discourse. Discourse can be seen as a

Risks of alcohol and drug use disorders in prostate cancer survivors : a national cohort study

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-