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Welcome to the Department of Automatic Control The Department of Automatic Control conducts research and education in dynamical systems, learning, and control. The department offers courses at both introductory and advanced levels within the engineering programs, addressing students from a broad range of engineering disciplines. Our vision is to be "A world class department that explains, explores

https://www.control.lth.se/start - 2026-06-19

Kontrastmedels och förebyggande hydrerings påverkan på njurfunktionen

Inledning: Inom röntgenverksamheten utförs undersökningar med kontrastmedel för klinisk diagnostik. Kontrastmedelinducerad njurskada förekommer vid administrering av kontrastmedel. Syfte: Syftet med studien var att beskriva kontrastmedels påverkan på njurfunktionen och om hydrering kan minska eventuell negativ påverkan. Metod: Denna studies design är en icke-systematisk litteraturstudie. Artiklar

Jaco Zuijderduijn

Universitetslektor Kontaktinformation E-post: jaco [dot] zuijderduijn [at] ekh [dot] lu [dot] seOrganisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa1:2109 Hämtställe: 10 WebbplatsJaco Zuijderduijns profil i Lunds universitets forskningsportalAndra roller Universitetslektor Finanshistoria, banker och försäkringar Universitetslektor Tillväxt, teknolo

https://www.ehl.lu.se/jaco-zuijderduijn - 2026-06-19

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Prevention and Management of Bleeding Episodes in Children with Hemophilia

Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

Induction of platelet thrombi by bacteria and antibodies.

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller