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Background: Data on rescue treatment of autoimmune hepatitis in patients that fail standard treatment are sparse. Aims: To report our long-term experience with mycophenolate mofetil. Methods: Retrospective study in 22 patients with autoimmune hepatitis who failed azathioprine and prednisolone due to adverse events (n = 14, 64%), lack of remission (n = 5, 23%) or a combination (n = 3, 13%). Results

Available studies on visual field disturbances in diabetic retinopathy have shown conflicting results, obtained with different and often non-comparable techniques. We have studied visual fields at different stages of diabetic retinopathy with modern sensitive computerized technique taking precautions to limit disturbing effects of random field variation and lack of perimetric experience. Sixty-thr

There is a growing political consensus in the European Union (EU) to move away from the current resource intensive “linear” economic system, towards an innovative system aiming at closing material loops – the so-called circular economy. An array of new policy proposals targeting all stages of the life-cycle of a product are needed to facilitate the transition to a circular economy in Europe. While

Purpose: Tru-cut biopsy is a minimally invasive technique used to obtain tissue samples for the diagnosis of tumors, especially in patients where primary surgery is not indicated. The aim of this study was to assess the adequacy, accuracy and safety of the tru-cut biopsy for diagnosis in gynecological cancer.Methods: A retrospective population-based review of 328 biopsies was conducted. The indica

INTRODUCTION: Thorough treatment planning is essential for a good clinical outcome in orthognathic treatment. The planning is often digital. Both 2-dimensional (2D) and 3-dimensional (3D) software options are available. The aim of this randomized 2-arm parallel double-blinded active-controlled clinical trial was to compare the outcomes of computer-based 2D and 3D planning techniques according to p

Registered Nurses (RNs) are in the immediate position to provide End-of-life (EOL) care and counselling for patients and families in various settings. However, EOL-care often creates feelings of uncertainty and inadequacy linked to inexperience, lack of education, and attitude. To identify and describe factors associated with RNs' attitudes towards EOL-care, and to identify whether and how these a

Background: Mothers of preterm infants are at greater risk of symptoms of stress and anxiety compared to mothers of term infants. Aims: This study aimed to explore mothers’ experiences after coming home from the hospital with a moderately to late preterm infant. Methods: A qualitative and explorative method was used. Ten mothers who had given birth to a preterm baby with a gestational age between

Objective: This paper analyses intergenerational relationships in Sweden during the corona pandemic, with a special focus on practices of care. The research question is: How is care between generations – between grandparents, adult children and grandchildren – done during pandemic conditions? Background: In Sweden, where an extensive welfare state provides affordable child- and eldercare, the coro

OBJECTIVE: To explore physicians' thoughts and considerations of participation in medical decision making by hospitalised elderly patients.DESIGN: A qualitative study using focus group interviews with physicians interpreted with grounded theory and completed with a questionnaire.SETTING AND PARTICIPANTS: The setting was three different hospitals in two counties in Sweden. Five focus groups were co

Objective. To analyze the experience of a single centre using stent-grafts for treatment of complicated acute aortic type B-dissections (EVR-ABD). Design. Retrospective analysis of prospectively collected data from patients undergoing EVR-ABD between January 1997 and December 2004. Methods. EVR-ABD was performed in 31 patients (20 males, median age 74. years (IQR: 64-79)). Indications for treatmen

Den allmänna dataskyddsförordningen (förordningen) kommer att ersätta dataskyddsdirektivet (direktivet) år 2018. Europeiska kommissionen har ansett att direktivet inte längre ger det skydd av den personliga integriteten som enskilda har rätt till. Förordningen ska därför harmonisera reglerna, ge enskilda en ökad kontroll och samtidigt gynna den fria rörligheten av personuppgifter inom den EuropeisThe General Data Protection Regulation (GDPR) replaces the Data Protection Directive (Directive) in 2018. The European Commission has stated that the Directive no longer provides the protection of personal integrity that individuals are entitled to. The GDPR will harmonize the rules and its purpose is to give individuals a greater control over their data and ensure the free movement of personal da

A section of the Swedish library act stipulates that libraries are to pay specific attention to people with disability. Exhaustion syndrome is a mental disability that in recent years has started to grow rapidly in numbers. This master thesis is mainly aiming to study whether public libraries are welcoming and functional places for people with exhaustion syndrome but it also has a wider scope stud

Jämfört med många andra industrier så har byggnadsindustrin halkat efter med att implementera digitala lösningar. I dagsläget är det enbart ett fåtal materialleverantörer och tillverkare som erbjuder en tjänst av så kallade digitala BIM-objekt till sina produkter. Dessa digitala produkt kopior kan nyttjas för flera syften i projektmodeller vilket exempelvis gynnar desing-team och entreprenörer. DeThe construction industry has in general been rather slow in its implementation of new digital solutions compared to other industries. To date, only a handful of material suppliers are offering a service of so-called digital BIM-objects of their products. These 'digital product copies' can be utilized in projects' BIM-models for several purposes, being favorable to the design team and

Debts among individuals and households in Sweden have increased over the years. Although statistics from the Swedish Enforcement Authority show that the total number of people registered with excessive debts has declined for the third year in a row, the total amount of debt of those individuals and households who are already overindebted on other hand continues to increase. Moreover, debtors regis

Detta examensarbete ger ett förslag på en ny järnvägsstation i Kirunas nya centrum. I Kiruna pågår just nu en stadsomvandling, där en tredjedel av staden flyttas tre kilometer österut på grund av markdeformationer från Kirunagruvan. Detta innebär stora förändringar för Kirunaborna men även stora förändringar i stadsbilden, då majoriteten av centrum har eller kommer rivas och byggas upp igen i nya This thesis gives a suggestion for a new railway station in the new city center of Kiruna, Sweden. Kiruna is now experiencing an urban transformation, where one third of the population and the city moves three kilometers to the east due to ground deformations coming from the Kiruna iron ore mine. This leads to huge changes for Kiruna’s population, but also huge changes in the cityscape, since most

“The code that guides the Path” Geosmin is a volatile metabolite that smells like the earthy odorant that is mostly predominant after a heavy rain fall; what produces this intensive surge of geosmin in the air is from the spore producing family streptomycetaceae. Not only do these bacteria produce a scent that most people find pleasant to smell, they also play a key role in modern society. Why th

Objective. Several classification systems have been launched to characterize Barrett's esophagus (BE) mucosa using magnification endoscopy with narrow band imaging (ME-NBI). The good accuracy and interobserver agreement described in the early reports were not reproduced subsequently. Recently, we reported somewhat higher accuracy of the classification developed by the Amsterdam group. The critical

Popular Abstract in Swedish Arbetsförmåga har kommit att bli ett viktigt begrepp i samhället, men också för individen. Det saknas i dag en tydlig definition av arbetsförmåga, trots att det har en stor inverkan på hur sjukförmåner distribueras och också för den enskilde individens möjlighet att försörja sig. I västvärlden är arbetsförmåga ofta diskuterat i relation till sjukskrivning och en åldrad The overall aim of this thesis was to deepen the understanding of work ability by analyzing how different health professionals experience and perceive work ability and assessments of work ability, and also by analyzing rehabilitation outcomes that are related to work ability. The focus has been on musculoskeletal disorders with associated psychosocial factors. Method. The general approach was indu