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With the risk of climate breakdown, pressure is increasing for all sectors of the economy to break with fossil fuel dependence and reduce greenhouse gas emissions. In this context, the chemical industry requires more focused attention as it uses more fossil-fuel based energy than any other industry and the production of chemicals is associated with very large emissions. Beyond the climate crisis,
In this paper we report the investigation of the laser-induced breakdown and ignition behaviour of methane/air and dimethyl ether (DME)/air mixtures. Moreover, the optical emission from the induced plasma is utilized for determining the mixture composition quantitatively by means of laser-induced breakdown spectroscopy (LIBS). To the best of the authors' knowledge, LIBS and laser ignition of DME h
To determine benefits and harms of arthroscopic knee surgery involving partial meniscectomy, debridement, or both for middle aged or older patients with knee pain and degenerative knee disease.
We introduce a density functional formalism to study the ground-state properties of strongly correlated dipolar and ionic ultracold bosonic and fermionic gases, based on the self-consistent combination of the weak and the strong coupling limits. Contrary to conventional density functional approaches, our formalism does not require a previous calculation of the interacting homogeneous gas, and it i
Many environmental risk factors for hepatobiliary cancers are known but whether they are associated with specific cancer types is unclear. We present here a novel approach of assessing standardized incidence ratios (SIRs) of previously diagnosed comorbidities for hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cholangiocarcinoma (CCA) and ampullary cancer. The 13 comorbidities included a
This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of pac
The liver is a central metabolic hub, performing vital functions such as bile production, protein, carbohydrate, lipid and drug metabolism, detoxification of xenobiotics, and the synthesis of essential biomolecules for reproduction, and also shows regenerative capability. Several of these functions can be affected by sexual dimorphisms with important consequences. In this study we used high-throug
In recent decades, a significant advancement in the Global Navigation Satellite System (GNSS) has been adopting the vector tracking (VT) technique, particularly in environments where stable and reliable positioning is essential. It facilitates rapid reacquisition and continuous tracking of GNSS signals by linking the data processing and signal processing modules. In challenging environments affect
Selective inhibitors could help unveil the mechanisms by which inhibition of poly(ADP-ribose) polymerases (PARPs) elicits clinical benefits in cancer therapy. We profiled 10 clinical PARP inhibitors and commonly used research tools for their inhibition of multiple PARP enzymes. We also determined crystal structures of these compounds bound to PARP1 or PARP2. Veliparib and niraparib are selective i
In this paper the choices of control variables and control structures are investigated for the Open Plate Reactor. Since the process design is very flexible, it allows many different control structures and variables and it may be non-trivial to find the most suitable choice. Analysis with the Relative Gain Array indicates that the flexible process configuration of the OPR enables a decentrali
Recent estimates by the World Health Organization show that one in six people globally experience infertility at some point in their lives. Infertility is a fundamental reproductive health concern affecting an individual's human right to freely decide if, when, and how many children to have. A growing body of literature notes infertility’s absence from the sexual and reproductive health and ri
