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While research on the design of heterogeneous concurrent systems has a long and rich history, a unified design methodology and tool support has not emerged so far, and thus the creation of such systems remains a difficult, time-consuming and error-prone process. The absence of principled support for system evaluation and optimization at high abstraction levels makes the quality of the resulting im
FK506 binding protein 65 (FKBP65) belongs to a group of proteins termed immunophilins that have a high binding affinity to immunosuppressant drugs as FK506 (tacrolimus) and rapamycin (sirolimus). Treatment of female premenopausal women with tacrolimus, which binds to FKBP65, has been reported to be followed by a strongly increased risk of ovarian cysts. We performed the present study to reveal how
1. Dementia is a clinical syndrome with several causes whichcreates impairments in mental ability, personality, affect andsocialisation.2. Information from family members can be very useful in theearly identification of cognitive impairment.3. Patients presenting with cognitive impairment should be evaluatedfor potentially reversible causes, with a range of laboratorytests and investigations.4. Sh
This paper describes some research stimulated by a fundamental shift that is occurring in the manufacture and marketing of aero engines for commercial and defence purposes, away from the selling of products to the provision of services. The collaborating aerospace company offers contracts under which it remains responsible for the maintenance of engines which have been purchased by airlines throug
I en studie av neutralisationskapaciteten och kalkstenshalten i Sydvattens infiltrationsområde vid Vomb har fem prover från olika platser i fältet samlats in, siktats och surgjorts med saltsyra. Neutralisationskapaciteten mätt som kalciumkarbonathalt befanns variera i de olika sandproverna men var generellt hög (ca 2–14 % som vikt). Den totala massan av kalciumkarbonat i infiltrationsområdet bestäIn a study of the neutralization capacity and limestone content the artificial recharge area of the Sydvatten waterworks Vombverket in Vomb, Skåne, five samples from different locations in the area was collected, sieved and acidified with hydrochloric acid. The neutralization capacity measured as calcium carbonate content was found to vary in the different sandy soil samples but was generally high
This chapter concerns disabled people’s experiences of barriers to accessing sexuality. It draws on an analysis of materials produced in ten projects by civil society organisations, including self-advocacy organisations, sexual rights organisations and organisations working on behalf of disabled people. These materials comprise books, handbooks, videos, websites and other online materials, and are
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested stra
A microenvironment is an area with a specific composition of mainly extracellular matrix (ECM) components surrounding the cells. The tight interactions between matrix molecules and cells are very important, and it is now well known that the ECM components direct cell activity and function and regulate remodeling processes during both homeostasis and pathological conditions. The lung is a very comp
Quinoa (Chenopodium quinoa Willd.) has gained recent popularity mainly due to its attractive nutritional profile and its ability to grow under extreme conditions such as salinity, acidity, drought, flooding, and frost as well as the functionality of its component. Starch is the main component of quinoa grain which constitutes up to 60% of the dry grain and plays a crucial role in the functional pr
This chapter presents two case analyses, one situated in Sweden and the other in Poland, where attempts have been made to intervene in the existing laws regulating access to abortion. The first case involves the lawsuits filed by midwives in Sweden who claimed to have been discriminated against on the grounds of their religion when they had been turned down for work due to their objection to perfo
A stochastic hierarchical model for the evolution of low grade gliomas is proposed. Starting with the description of cell motion using a piecewise diffusion Markov process (PDifMP) at the cellular level, we derive an equation for the density of the transition probability of this Markov process based on the generalised Fokker–Planck equation. Then, a macroscopic model is derived via parabolic limit
This paper considers the dual approach to conspiracy theories in anthropological studies. While some anthropologists suggest treating them seriously because they might reveal some truths, others argue that conspiracy theories require serious attention, because they are alarming and present a threat to social cohesion and democracy. Analysing conflicts over HPV immunisation programmes in Ireland, t
