Search results

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, but the average magnitude of these risks is uncertain and may depend on the context. Estimates based on multiple-case families may be enriched for mutations of higher risk and/or other familial risk factors, whereas risk estimates from studies based on cases unselected for family history have been imprecise. We p

Transgenic Huntington's disease (HD) mice, expressing exon 1 of the human HD gene (lines R6/1 and R6/2), are totally resistant to striatal lesions caused by the NMDA receptor agonist quinolinic acid (QA). Here we show that this resistance develops gradually over time in both R6/1 and R6/2 mice, and that it occurred earlier in R6/2 (CAG-155) than in R6/1 (CAG-115) mice. The development of the resis

Objective. Recent work has shown that several soluble biomarkers, detectable in peripheral blood, synovial fluid, and/or urine, reflect remodeling of joint tissues and may therefore constitute outcome measures that reflect joint damage. Consequently, it is now desirable to begin the process of developing criteria for validation of a soluble biomarker as an outcome measure reflecting structural dam

Atrial fibrillation (AF), the most common atria[ arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic therapy, 'upstream therapy') only prevent a part of this burden of disease. New treat

This paper presents results of technical, functional and stylistic analyses on pottery from two Early Neolithic sites on Öland – Resmo and Runsbäck. Analyses include thin sections and XRF of clays and wares, lipid residue analysis and recording of stylistic attributes. The two sites are situated 15 km apart on the west side of the island. C14 dates place the activities at the sites at c. 3900 3600

The results of a search for pair production of supersymmetric partners of the Standard Model third-generation quarks are reported. This search uses 20.1 fb(-1) of pp collisions at root s = 8 TeV collected by the ATLAS experiment at the Large Hadron Collider. The lightest bottom and top squarks ((b) over tilde (1) and (t) over tilde (1) respectively) are searched for in a final state with large mis

Encephalitis is one of the manifestations of infection with Epstein-Barr virus with clinical outcome varying from complete recovery to death. A 16-year-old boy with Epstein-Barr virus encephalitis with global cortical and subcortical gray matter involvement and a full clinical recovery is reported. The case inspired a literature review which yielded 100 cases of Epstein-Barr virus encephalitis sub

Øresund EcoMobility contributes to knowledge creation for sustainable transport and green logistics, city transport, and energy systems with a specific focus on the conditions and needs of the Øresund region. In this book, long distance goods transport and strategies for green corridors through the Øresund and Europe are studied, multi-criteria models for analysis in transport and infrastructural

The main topic of this Thesis is the x-ray spectroscopic studies of free nano-clusters with size more than 10^3 atoms. The photoelectron spectroscopy experiments on rare gas and metal clusters were performed at beamline I411 at MAX-lab National Swedish synchrotron radiation facility. Free rare-gas clusters are simplest objects in cluster research. However their electronic structure springs a lot

Background: Pulse wave velocity (PWV) is a biomarker for arterial stiffness, clinically assessed by applanation tonometry (AT). Increased use of phase-contrast cardiac magnetic resonance (CMR) imaging allows for PWV assessment with minor routine protocol additions. The aims were to investigate the acquired temporal resolution needed for accurate and precise measurements of CMR-PWV, and develop a t

Purpose To study prevalence of diabetic retinopathy (DR) at diagnosis (DRAD) and to estimate contributing risk by sociodemographic, cardiovascular and metabolic characteristics present in patients recently diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA). Methods Patients (n = 2174) recently diagnosed T2D (93%) or LADA (7%) were included upon arrival for their

Purpose: It has been proposed that biological/chemical substances in the intestine might play a role in the occurrence and deterioration of perianal fistulas. Elimination of such unidentified factors from the lower gastrointestinal tract might offer a new strategy for the management of anal fistulas. The aim of this study was to evaluate the clinical effects on non-Crohn’s disease perianal fistula

Background: The aim of this study was to identify corresponding body mass index (BMI) and waist circumference cut-offs for equivalent levels of insulin sensitivity in a Middle Eastern immigrant population compared with native Swedes. Methods: Citizens of Malmö, Sweden aged 30 to 75 years, who were born in Iraq or Sweden, were in 2010-2012 invited to participate in a health examination including an

In England saltmarshes account for less than 0.5% of the land area; however they have a very high biodiversity value and provide significant economic and social services. Climate change, continuous coastal urbanisation and port development are serious concerns for coastal protection planners, city councils and state government agencies interested in balancing the social, economic and environmental

OBJECTIVES: We examined approaches to reduce sodium content of food served in settings operated or funded by the government of the County of Los Angeles, California.METHODS: We adapted health impact assessment methods to mathematically simulate various levels of reduction in the sodium content of food served by the County of Los Angeles and to estimate the reductions' potential impacts on mean sys

We present a vertical nanowire InAs/GaAsSb/GaSb TFET with a highly scaled InAs diameter (20 nm). The device exhibits a minimum subthreshold swing of 48 mV/dec. for Vds = 0.1-0.5 V and achieves an Ion = 10.6 μA/μm for Ioff = 1 nA/μm at Vds = 0.3 V. The lowest subthreshold swing achieved is 44 mV/dec. at Vds= 0.05 V. Furthermore, a benchmarking is performed against state-of-the-art TFETs and MOSFETs

Kirurg som kombinerade konstintresse med medicinsk forskning Professor Philip Sandblom(1903-2001), framstående kirurg och Lunds universitets rektor 1957-68, kombinerade sitt stora konstintresse med medicinsk forskning. Han studerade bland annat sambandet mellan sjukdom och konstnärligt skapande.Philip Sandblom föddes av svenska föräldrar i Chicago, USA 1903. Familjen flyttade senare till Sverige v

https://www.medicin.lu.se/medicinska-fakulteten-vid-lunds-universitet/fakultetens-historia/philip-sandblom - 2026-07-11