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Background: The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the association between zinc intake and T2D may be modified by the SLC30A8 genotype. Results: We carried out a pro

The integrated dynamic ecosystem models SAFE and ForSAFEVEG were used to estimate critical loads for nitrogen using different chemical and biological criteria, and attempting to account for possible effects of climate change. The study is based on a model application on a set of 640 sites earlier used for critical loads assessments in Sweden, focusing on the ecological effect of nitrogen pollution

Objective: The primary objective was to evaluate 6-month outcomes for brief and extensive automated telephony interventions targeting problematic alcohol use, in comparison to an assessment-only control group. The secondary objective was to compare levels of problematic alcohol use (hazardous, harmful or probable dependence), gender and age among study participants from clinical psychiatric and ad

Purpose: Managing focal cartilage injuries in the middle-aged patient poses a challenge. Focal prosthetic inlay resurfacing has been proposed to be a bridge between biologics and conventional joint arthroplasty. Patient selection and accurate implant positioning is crucial to avoid increased contact pressure to the opposite cartilage surface. A customized femoral condyle implant for focal cartilag

A dose survey of positron emission tomography (PET) examinations was performed in 12 regions of the Russian Federation, where the effective dose values were assessed for the various types of PET examinations. The comparison to similar published data show that the patient doses in Russia are higher than in other countries. Low-dose CT protocols and justification of multiphase CT protocols should be

Background: The aim of this study was to investigate graft preservation, major bleeding, and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSIs) in the groin after vascular surgery and factors associated with failure of treatment. Methods: Retrospective data were collected during 2004-2015. Failure of wound treatment was defined as a wound

Many automated gating algorithms for flow cytometry data are based on the concept of unimodal cell populations. However, in this article, we show that criteria previously used to make decisions on unimodality cannot adequately distinguish unimodal from bimodal densities. We show that dip and bandwidth tests for unimodality, taken from the statistics literature, can do this with consistent and low

This thesis is a phenomenological investigation into the differences and similarities between language as speech and language as a technique. Speech is the practice of producing and understanding utterances. A technique is the organizing mechanism of speech, the structure that gives it a regular form. While speech is heavily dependent on context and interpretation, a technique is unaffected by theThis thesis is a phenomenological investigation into the differences and similarities between language as speech and language as a technique. Speech is the practice of producing and understanding utterances. A technique is the organizing mechanism of speech, the structure that gives it a regular form. While speech is heavily dependent on context and interpretation, a technique is unaffected by the

Electromagnetic compatibility (EMC) is a vital part of product development, and understanding the sources and causes of the emissions can facilitate tremendously in reaching compliance requirements and reduce the work needed for troubleshooting. At Axis Communications, where this thesis has taken place, the knowledge of EMC is an important part of their work and they aspire to improve further. Thi

Concerto for Double Bass and Orchestra by Eduard Tubin is considered to be one of the most challenging pieces of the double bass repertoire as it is known to be a physically demanding work. It was written for double bass player Ludvig Juht who was a physically big built man and welcomed the technical challenges. This thesis aims to analyze these challenges of the piece for a player with smaller ph

Voluntary Carbon Markets (VCM) have emerged with the intention of supporting decarbonisation and carbon dioxide removal solutions around the world. However, and despite a rapid growth, the motivations and preferences of the demand side to engage in with the VCM have not been thoroughly studied before. Iceland, the focus of this thesis, exemplifies this trend. To address this knowledge gap, this th

This study aims to identify the most cost-effective and environmentally friendly retrofit solutions for enhancing the energy efficiency of second homes in Sweden. Second homes, often used intermittently throughout the year, represent a significant portion of residential energy use and carbon emissions. Therefore, optimizing energy consumption in these homes is critical for achieving national and g

Soil moisture (SM) is an essential climate variable that controls fundamental hydrological and climatic processes. Soil moisture products derived from microwave remote sensing often provide measurements at low spatial resolution and incomplete temporal records. This thesis presents a novel method for estimation soil moisture at both high spatial and temporal resolution by using a deep learning rec

Microgrids and distributed renewable energy have the potential to facilitate management and adaptation for climate change. While research on microgrids has been developing for the past decades, further studies are necessary to expand on business models and scenarios which lead to their successful commercialization and implementation. This study applied the business model canvas as an analytical fr

This project has developed from the site and building conditions in an area of central Boden, a town in the inland north of Sweden. In post-war times, the city grew thanks to the military and regional hospital resulting in the development of the site Prästholmen that was realized true to the modernistic ideal of the time. Since then, Boden together with its inland neighbours, have struggled agai

Electric cars are by many considered a sustainable solution to the ever-growing demand for road vehicles and fuel. The transportation sector is responsible for almost a third of the total greenhouse gas emissions globally and approximately 80% of these emissions can be attributed to road vehicles. Thus, there is an urgent need for a shift away from fossil fuels in the sector. While the consumer in

As Special Purpose Acquisition Companies (SPACs) are becoming the increasingly popular method of taking a company public, the lack of research on abnormal returns for this asset class since its introduction to the major exchanges validates a reason to expand the investigation. This thesis examines the potential abnormal returns found in different stages of recent SPACs lifecycle, dividing the SPAC

This study aims to examine the online afterlife of the slasher film Sleepaway Camp (1983, Robert Hiltzik) and how this afterlife relates to the queer elements in the film and its role as a cult film. By combining analytical perspectives and tools deriving from film studies and media studies, through applying film analysis as a method and using a netnographic approach, the fields complement each ot