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Moraxella IgD-binding protein (MID) is a well characterized trimeric autotransporter that specifically targets the IgD of B cells. We fused the membrane anchor of the meningococcal autotransporter NhhA with the IgD-binding region of MID (aa 962-1200) to create a chimeric protein designated as NID. The aim was to use this specific targeting to provide a better vaccine candidate against meningococci
Since a tightly regulated complement system is needed for a successful pregnancy, we hypothesized that alterations in complement inhibitors may be associated with idiopathic, recurrent miscarriage. We sequenced all exons coding for three complement inhibitors: C4b-binding protein (C4BP), CD46 and CD55 in 384 childless women with at least two miscarriages that could not be explained by known risk f
Compression anastomotic ring-locking procedure (CARP) is a novel procedure for creating colonic anastomoses. The surgical procedure allows perioperative quantification of the compression pressure between the intestinal ends within the anastomosis and postoperative monitoring of the anastomotic integrity. We have recently shown that CARP is a safe and effective method for colonic anastomoses in pig
We have investigated methods of starch dissolution with the aim of finding an optimum method to completely dissolve starch granules to form a molecularly dissolved starch solution without degradation of the polymers. Glycogen was used as a model molecule for amylopectin, to identify the dissolution conditions under which the degradation of the polymers was limited or not present. Dissolution was p
A search for direct production of supersymmetric gauginos and sleptons in final states with two and three leptons is presented. The two lepton analysis uses 4.7 fb(-1) of proton-proton collision data at root s = 7 TeV, while the three lepton analysis uses 13 fb(-1) at root s = 8 TeV. All data were recorded by the ATLAS detector at the Large Hadron Collider. The results are interpreted in the pheno
Macro and micronutrient deficiencies are a significant problem among people in rural areas in developing countries. Deficiencies may lead to an impaired immune system making the organism vulnerable to infections and diseases. In this paper, the dietary intake, anthropometric measurements, zinc and copper levels in serum, of patients with cutaneous leishmaniasis (CL) are compared with a group of he
This paper presents a 1MHz bandwidth, ΔƩ fractional-N PLL as the frequency synthesizer for LTE. A noise cancellation path composed of a novel hybrid ΔƩ DAC with 9 output bits is incorporated into the PLL in order to cancel the out-of-band phase noise caused by the quantization error. Further, a re-timing circuit is proposed to reduce the nonlinearity in the Charge Pump and provide pulse shaping si
Most wastewater treatment plants contain an activated sludge process, which consists of a biological reactor and a sedimentation tank. The purpose is to reduce the incoming organic material and dissolved nutrients (the substrate). This is done in the biological reactor where micro-organisms (the biomass) decompose the substrate. The biomass is then separated from the water in the sedimentation tan
This work concerns the performance of an oxidation catalyst used in a NOx storage and reduction system. The oxidation of NO is the main objective of this study, where the presence of CO and propene has also been taken into account. Experimental data has been determined on a monolithic oxidation catalyst mounted after a heavy duty diesel engine in a rig. The conversion of hydrocarbons is predicted
In the development of new food products, more knowledge is needed about the occurrence and quantity of food-borne pathogens in the food chain to be able to implement effective control measures and assure food safety. In addition, improved understanding of how environmental factors and food preservatives effect the microbial virulence expression in foods will enable the formulation of new strategie
The International Energy Agency’s (IEA) Task 41: Solar Energy and Architecture gathers researchers, academics and practicing architects from 14 countries in a project pursuing the objectives to identify and address obstacles that architects are facing in solar design. Part of this three-year project is the development of an international survey -intended for practicing architects- addressing a bro
In addition to being a key criterion of the sustainable development proviso, for business, the integration of social- and ecological considerations into decision-making is of growing importance for minimising future environmentally-related risk and associated economic costs, as well as gaining a share in growing markets favouring products and companies focusing upon social responsibility and ecolo
In an era of lifelong learning, empowerment of the learner becomes fundamental. Therefore ex-ploitation of the full potential of learning objects depends upon creation of an appropriate infra-structure to promote symmetrical control of inquiry. The learner needs to be empowered because learning is a discovery process and thus must be under his or her own control. In early stages of education it
Popular Abstract in Swedish Patienten med underbensamputation på grund av kärlsjukdom Långt före Kristi födelse var amputation av benet en känd operation. Anledningen till amputationen kunde vara kärlsjukdom, olycksfall, tumör eller medfödda missbildningar. I västvärlden idag utförs 90 % av amputationerna på grund av kärlsjukdom. Dessa patienter är äldre och sjukare än övriga benamputerade och meThe patient with unilateral trans-tribal amputation for vascular disease. Functional assessments, prognostic factors and cost of prostheses. The aims of the study were to focus on the functional ability of the dysvascular patient with unilateral trans-tibial amputation and the early rehabilitation period, defined here as the period between the amputation and the prosthetic fitting. Results revea
The paper presents results of a study on the use of the NOAA AVHRR data for desertification monitoring on a regional-global level. It is based on processing of the GIMMS 8 km global NDVI data set. Time series of annual integrated NDVI and standardized annual NDVI anomalies from the 1981-2003 periodic means were compared with a corresponding rainfall data set (i.e. 1981-2003) as well as a historica
Associations with functional groups of natural organic matter (NOM) are of great importance for bioavailability, toxicity, and mobility of trace metals in soils and waters. In this study, the coordination chemistry of copper, Cu(II), in organic soils and dissolved organic matter (DOM) from soils and streams was investigated by extended X-ray absorption fine structure (EXAFS) spectroscopy. In both
Mirtazapine pharmacokinctic (PK) data from patients on long-term treatment for major depression have never been investigated. For this reason, in a large naturalistic outpatient study (prospective, multicenter, open-labeled, and noncomparative) conducted in Sweden in the period 2000 2002, one of the main objectives was to outline the inter- as well as intraindividual PK variance of mirtazapine and
