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Background: Refugees and asylum-seekers have an elevated risk of mental health issues, such as depression and posttraumatic stress. Qualitative outcome studies can contribute by offering insight into patients’ experiences of what they find beneficial and how they undergo the process of recovery. This study aligns with the small body of qualitative research focusing on refugees’ perspectives of psy
The human gastrointestinal tract (GIT) is home to a large community of microorganisms that contribute to human health. Delivering live bacteria to the gut for therapeutic purposes can thus be highly beneficial. However, delivering live biotherapeutic products or probiotic bacteria to the GIT presents challenges because the cells must remain viable during production, storage, and administration. En
The Particle Finite Element Method (PFEM) is attractive for the simulation of large deformation problems, e.g. in free-surface fluid flows, fluid–structure interaction and in solid mechanics for geotechnical engineering and production processes. During cutting, forming or melting of metal, quasi-incompressible material behaviour is often considered. To circumvent the associated volumetric locking
Background: Osteonecrosis (ON) is a potentially disabling skeletal complication of cancer treatment. Although symptomatic osteonecrosis (sON) is well-known in acute lymphoblastic leukemia (ALL), with an incidence around 6%, studies on sON in pediatric Hodgkin lymphoma (HL) are scarce. The aim of this study was to examine the incidence, risk factors, and outcome of sON in children treated for HL. P
Accurate regulation of microfilament dynamics is central to cell growth, motility and response to environmental stimuli. Stabilizing and depolymerizing proteins control the steady-state levels of filamentous (F-) actin. Capping protein (CP) binds to free barbed ends, thereby arresting microfilament growth and restraining elongation to remaining free barbed ends. In all CPs characterized to date, a
BACKGROUND: Anastomotic leakage after rectal cancer surgery is linked to reduced survival and higher recurrence rates. While an aggravated inflammatory response may worsen outcomes, few studies have explored the combined effects of leakage and inflammation.METHODS: This is a retrospective multicenter cohort study including patients operated with anterior resection for rectal cancer in Sweden durin
Background and Objective: This narrative review addresses idiopathic acute pancreatitis (IAP) and its epidemiology, diagnosis, clinical course and treatment during the last decade. As there is no previously validated protocol for finding the aetiology of acute pancreatitis (AP), the primary aim of this study is to find, describe and unify evidence about the diagnostic work-up of AP to diagnose the
The global energy landscape is entrenched in fossil fuels, shaping modern life profoundly. Germany, a prominent example, grapples with transitioning from its fossil-fuelled infrastructure despite governmental support for decarbonization. Carbon capture and storage (CCS) and hydrogen appear as crucial tools in this transition. A recent partnership between Germany and Norway seeks to leverage Norway
In dynamic operational environments, particularly in collaborative robotics, the inevitability of failures necessitates robust and adaptable recovery strategies. Traditional automated recovery strategies, while effective for predefined scenarios, often lack the flexibility required for on-the-fly task management and adaptation to expected failures. Addressing this gap, we propose a novel approach
The year 2015 marked a rupture in the post-war development of refugee reception and integration policies in Sweden. This rupture involved both a radical change in refugee policy and practice, and a rupture in the long-held collective self-image of Sweden as a country with generous reception and integration policies (Scarpa & Schierup 2018). This article responds to the question of how social wThe year 2015 marked a rupture in the post-war development of refugee reception and integration policies in Sweden. This rupture involved both a radical change in refugee policy and practice, and a rupture in the long-held collective self-image of Sweden as a country with generous reception and integration policies (Scarpa & Schierup 2018). This article responds to the question of how social w
Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete, uns
Hydrogen stands out as a compelling alternative to fossil fuels for combustion engines. Predictive combustion models are instrumental in developing hydrogen-fuelled engines. A fundamental metric of these models is the laminar burning velocity (LBV), which can be precisely determined through laminar flame propagation simulations. In this context, the selection of an appropriate combustion mechanism
The cultivated peanut (Arachis hypogaea L.) is an important oilseed crop worldwide, and fatty acid composition is a major determinant of peanut oil quality. In the present study, we conducted a genome-wide association study (GWAS) for nine fatty acid traits using the whole genome sequences of 160 representative Chinese peanut landraces and identified 6-1195 significant SNPs for different fatty aci
In this study, a comprehensive investigation of a set of phytochemicals to identify potential inhibitors for the Forkhead box protein M1 (FOXM1) was conducted. FOXM1 is overexpressed in glioblastoma (GBM) cells and plays a crucial role in cell cycle progression, proliferation, and invasion. FOXM1 inhibitors have shown promising results in preclinical studies, and ongoing clinical trials are assess
Mixed-phase clouds contain both supercooled cloud liquid and ice crystals. In principle, precipitation may be initiated either by the liquid phase or by the ice phase. Ice crystals may grow by vapor diffusion to become snow ("ice crystal process"), forming "cold"precipitation. Equally, cloud droplets, when large enough, coalesce to form "warm"precipitation by the "warm rain process."Warm rain coul
The Nobel Prize in Literature to the Austrian writer Peter Handke in 2019 gave new attention to one of the basic, and historically highly disputed (cf. Espmark 2001, 2021), questions in relation to the practice of the world’s most important literary prize – on what grounds, aesthetic or otherwise, does the Swedish Academy award the prize? In the aftermath of the 2019 prize to Handke, there was an
Cork oak and pine bark, two of the most prolific byproducts of the European forestry sector, were assessed as biosorbents for eliminating potentially toxic elements (PTEs) from water-based solutions. Our research suggests that bioadsorption stands out as a viable and environmental eco-friendly technology, presenting a sustainable method for the extraction of PTEs from polluted water sources. This
Purpose: Despite increasing focus among scholars and practitioners on the design of product-service systems (PSS), there exists no compilation of current knowledge on the role played by small and medium-sized enterprises (SMEs) in designing such systems. Thus, this paper sets out to identify and organise the existing research and suggest questions for future research. Design/methodology/approach:
