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A 3D nonlinear finite element analysis modelling framework was developed for simulating the behaviour of beams retrofitted with fibre reinforced polymer (FRP). The ABAQUS program was used for this purpose. Concrete was modelled using a plastic damage model. Steel bars were modelled as an elastic perfectly plastic material, with perfect bond between concrete and steel. A cohesive model was used for
Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related to other metabolic risk factors. We aimed to examine the risk of EAC and ESCC in relation to metabolic risk factors, separately and combined in a prospective cohort study. Metho
The impact of trade on environmental quality has received a considerable attention, both in policy debate and in theoretical literature. However, the empirical evidence on the topic remains lagged. This thesis adds to the empirics by unearthing the relationships and decomposing the effect into scale-technique effect and trade-induced composition effect using Arellano-Bond GMM estimation technique.
Climate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee
Popular Abstract in Swedish Förmaksflimmer är den vanligaste rytmrubbningen i hjärtat. Man beräknar att 1-2% av befolkningen har förmaksflimmer. Förmaksflimmer blir vanligare med stigande ålder. Bland personer äldre än 75 år har 5-10% förmaksflimmer. Var fjärde person över 40 år riskerar att drabbas av förmaksflimmer någon gång i livet. Förmaksflimmer ger bl.a. en ökad risk för blodproppar och strAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population, and a major cause of morbidity and mortality. Low-grade inflammation, erythrocyte volume variation, and subclinical atherosclerosis have repeatedly been associated with cardiovascular disease, but it remains unclear whether these risk factors are also associated with incident AF. This thesis is bas
Popular Abstract in English Microorganisms can be used for production of pharmaceutical substances. With the introduction of gene technology, it is possible to transfer information from one organism to the other, thereby making the receiving organism capable of producing substances that it did not so before. This development is very important for e.g. production of therapeutic proteins However, whMicroorganisms can be used for production of pharmaceutical substances. With the introduction of gene technology, it is possible to transfer information from one organism to the other, thereby making the receiving organism capable of producing substances that it did not so before. This development is very important for e.g. production of therapeutic proteins However, when using living organisms fo
This thesis examines the extent to which the judgment of the Court of Justice of the European Union in Commission v Belgium (C-524/23), regarding Belgium’s failure to comply with the Directive by failing to correctly transpose Article 8(7) of the Anti-Tax Avoidance Directive (ATAD) into its domestic legal framework, impacts the Dutch transfer pricing rules under Article 8b of the Corporate Income
Introduction: The extent to which pain is distributed across the body (spreading of pain) differs largely among patients with chronic pain conditions and widespread pain has been linked to poor quality of life and work disability. A longer duration of pain is expected to be associated with more widespread pain, but studies are surprisingly scarce. Whether spreading of pain is associated with clini
Purpose: The primary objective was to evaluate prescribing trends for topical ocular hypotensive treatment in the Nordic region during the last decade and, by population projections, estimate the glaucoma burden in 2040. A secondary objective was to analyse national variations in prescription patterns across the Nordic region. Methods: A retrospective analysis of national pharmacy data between 200
Background Drug use disorder (DUD) clusters in families due partly to shared environment, including sibling influences. Low academic achievement (AA) in adolescence increases DUD risk. This study examined whether low AA in an older sibling causally increases DUD risk in younger siblings. Methods We studied all Swedish full sibling pairs (n = 309,666) born 1972–1985 and ≤ 5 years apart. Older sibli
Background: Amyotrophic lateral sclerosis (ALS) is invariably fatal but there are large variations in the rate of progression. The lack of predictability can make it difficult to plan clinical interventions. This includes the requirement for gastrostomy where early or late placement can adversely impact quality of life and survival. Methods: We designed a model to predict the timing of gastrostomy
Accurate labels are critical for deriving robust machine learning models. Labels are used to train supervised learning models and to evaluate most machine learning paradigms. In this paper, we model the accuracy and cost of a common weak labeling process where annotators assign presence or absence labels to fixed-length data segments for a given event class. The annotator labels a segment as "pres
AimTo understand service users' experiences of their current mental health services and explore reflections on the Flexible Assertive Community Treatment (FACT) model and its role in future practice.MethodsA total of 17 experts participated in individual and dyadic in-depth interviews. A reflexive thematic analysis was performed on the participants' experiences of current mental health services anBackground: A person-centred and recovery-oriented approach is an integral part of modern mental health services founded on the experiential knowledge of service users. Their reflections as experts, grounded in their unique experience as service users, play a significant role in developing and improving the existing care. Experiential knowledge is therefore a means to enhance the relevance of rese
Background and aimHypoxic-ischaemic encephalopathy (HIE) is a leading cause of morbidity and mortality in unconscious patients resuscitated after out-of-hospital cardiac arrest. Many patients die after withdrawal of life-sustaining treatments (WLST), often due to a presumed poor prognosis. To minimise the risk of premature WLST, guidelines recommend using a multimodal prognostication. Head compute
In the late nineteenth and for much of the twentieth century, an academic career in Sweden was highly dependent on what grade a scholar’s doctoral dissertation was awarded. Unless receiving a so-called “docent grade”, basically declaring the scholar eligible for seeking the title of docent (associate professor), the prospects of maintaining an academic career were bleak. Throughout the period, thi
Purpose: Cognitive function is often impaired for cardiac arrest (CA) survivors due to hypoxic-ischemic brain injury. Whether cognitive impairment at hospital discharge is associated with recovery defined as functional status and fatigue measured at 1-month post-discharge is not known.Methods: Consecutive CA patients admitted at an academic center (May 14, 2021–June 23, 2023) were assessed for cog
Little is known about risk factors for central nervous system (CNS) relapse in mature T-cell and natural killer cell neoplasms (MTNKNs). We aimed to describe the clinical epidemiology of CNS relapse in patients with MTNKN and developed the CNS relapse In T-cell lymphoma Index (CITI) to predict patients at the highest risk of CNS relapse. We reviewed data from 135 patients with MTNKN and CNS relaps
Background. Survivors of sepsis may experience long-term risk of increased morbidity and mortality, but estimations of cause-specific effects beyond 1 year after a sepsis episode are lacking. Method. This nationwide population-based cohort study linked data from national registers to compare patients aged ≥18 years in Sweden admitted to an intensive care unit from 2008 to 2019 with severe communit
