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Both trio and population designs are popular study designs for identifying risk genetic variants in genome-wide association studies (GWASs). The trio design, as a family-based design, is robust to confounding due to population structure, whereas the population design is often more powerful due to larger sample sizes. Here, we propose KnockoffHybrid, a knockoff-based statistical method for hybrid a
Presented is the search for anomalous Higgs boson decays into two axion-like particles (ALPs) using the full Run 2 data set of 140fb-1 of proton-proton collisions at a centre-of-mass energy of 13TeV recorded by the ATLAS experiment. The ALPs are assumed to decay into two photons, providing sensitivity to recently proposed models that could explain the (g-2)μ discrepancy. This analysis covers an AL
Simulating the natural environment of living tissue with in vitro cell culture models has paved the way for scientific discoveries, and provided valuable insight into areas such as drug discovery and regenerative medicine. A new emerging technique of culturing cells on biomimetic three-dimensional scaffolds stands as a promising alternative to the traditional way of culturing cells on two-dimensio
The primary purpose of this paper is to further build on research related to capability development in order to explore hindrances and benefits of internal capability development and external partnerships as ways to improve performance. The beverage industry is used as the focus context since the companies in this industry are increasingly responding to external trends and looking for ways to deve
With the 11th century text Kitāb ādāb al-nikāḥ, the “Book on the Proper Conduct of Marriage”, the Islamic thinker al-Ghazālī (1056 –1111/447–504) replies to a contemporaneous debate within Sufi asceticism with a theology of nikāḥ. The text is part of his opus magnum, the “Renaissance of the Knowledge of dīn”, which aims at a renewal of Muslim piety and provides practical guidance to the male audie
The German transition to renewable energies has so far been an example of a successful energy transition of a major economy. Even though this transition is criticized for being only a half-hearted solution, it is an important example of the attempt of a major economy to transit towards renewable energies and is therefore worth studying in its own rights. Thus, my aim in this thesis is the identifi
This conceptual thesis analyses Carlota Pérez vision of a ‘Green Global Golden Age’ that is supposed to reconcile the tension between economic growth and sustainability (Pérez, 2016b). Aiming to address the pressing issue of continued unsustainability, Pérez’ proposed solution is based on the assumption that technological innovation in the field of Information and Communication Technologies (ICT)
Anthropogenic climate change and environmental degradation demand humanity to depart from the growth imperative forming the economic structure of the world. In other words: Structural transformation is needed. Much of the sustainability debate in academy, politics, media and the public revolves around two paradigms: minor changes within the current system (e.g. green consumption, green growth) or
Block copolymer lithography is a very promising candidate for nanoscale fabrication and is economically viable. It provides a high resolution, inexpensive, and straightforward approach to nano-size patterning. In this thesis, fundamental concepts and theories of block copolymer lithography are introduced. A well-controlled dynamic solvent vapor annealing chamber is built, and the best annealing co
Rockfalls occur around Sweden every year and the country lacks a national risk evaluation and an adequate regulatory framework for construction related to this natural hazard. The aim of this study is to address this problem by mapping areas under possible threat of rockfalls, considering two fundamental aspects: i) identification of the source areas and ii) estimation of the runout zones. The stu
Freezing injuries usually take place in thawed plant-based food products. To reduce freezing injuries, Pulse Electric Field (PEF) treatment and Vacuum Impregnation (VI) of cryoprotectant were used before the freezing process. The aim of PEF is to provoke electroporation to the membranes of the plant cells, thereby allowing the cryoprotective solution impregnated by VI to penetrate the cells. PEF
This thesis is a case study which investigates political parties’ reasons and driving forces for advocating an expansion of E6 in Skåne with respect to the fact that the highway today has reached its full capacity. The two biggest parties in the region, the Social Democratic Party and the Moderate Party, have been included in the research. The arguments stated by each party, revealed through semi-
This thesis project examines the dynamics of trespass protests, particularly focusing on the Right to Roam (RTR) movement in England. I ask in what ways trespass action for roaming rights challenges private property relations and embodies alternative relations to land and nature. Grounded in historical materialist and political-economic theories, private property is conceptualised as social and sp
Cancer är idag det näst vanligaste dödsorsaken i världen, där 30% av alla cancerfall bland kvinnor är bröstcancer. En vanlig behandling är bröstbevarande operation, där en bit av bröstet kirurgiskt tas bort. Operationer är både dyrt och har en betydande inverkan på kroppen och för vissa kvinnor krävs en omoperation efter den första operationen. Syftet med detta arbete har varit att undersöka möjliCancer is the second leading cause of death worldwide and 30% of all cancer cases among women are breast cancer. A popular treatment is breast-conserving surgery, where only a part of the breast is surgically removed. Surgery is expensive and has a significant impact on the body, and on some women, a reoperation is needed. The aim of this thesis was to see if there is a possibility to predict whet
Title: Exploring Coordination Mechanisms and Product Characteristics for Food Waste Reduction Principles: A Case Study in Physical Distribution Author: Zacharias Samuelsson Thesis supervisor: Eva Berg, Faculty of Engineering at Lund University Thesis Purpose: Identify food waste causes in a global distribution network and develop an improvement proposal for minimizing food waste. Method: This
The global food system, population growth, increased wealth, shifting diets and an overall larger demand for processed food, meat and dairy, has led to increased pressure on land, water and energy. The environmental implications of this have taken part in the establishment of international institutions which aims to regulate agriculture production methods, and thereby reduce these adverse impacts.
This thesis aims to analyse the borderline between private importation and retail sales of alcohol on the EU internal market. This thesis shows that according to the case-law of the Court of Justice of the European Union, the definition of private import is a complex assessment that depends on several factors. Among other indicators, it depends on the shipping and logistics procedure. To be classi
