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The assessment of the free water fraction in the brain provides important information about extracellular processes such as atrophy and neuroinflammation in various clinical conditions as well as in normal development and aging. Free water estimates from diffusion MRI are assumed to account for freely diffusing water molecules in the extracellular space, but may be biased by other pools of molecul
Lithium-ion battery safety is a topic of large importance, and testing is associated with large costs. Safety evaluation is therefore needed also at an early stage in cell design and development, in order to evaluate potential short-comings or to screen large platforms of materials and cells. Previous thermal runaway tests on lab-scale cells have, however, indicated differences in heat release and
BACKGROUND: In peritoneal dialysis, approximately 40% of the total osmotic ultrafiltration (UF) induced by glucose can be predicted to be due to "free" water transport across aquaporin-1 (APQ-1). Theoretically, it would be possible to assess the fraction of free water transport in the early phase of a hypertonic dwell, when UF rate is high and the relative contribution of Na+ diffusion is low. La
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
Around 50 million people worldwide suffer from Epilepsy, making it one of the most common neurological diseases. Epilepsy is characterized by sudden intermittent seizures, often imposing profound social and physical limitations. More importantly, the risk of premature death in these patients is up to three times that of the corresponding healthy population. It is estimated that 30% of the populati
2024 VT_LP2 FMAN25 CEQ Course evaluation ver 9.0 (2021-01-23) LTH Course evaluation report - CEQ, FMAN25 Basic facts Course name Calculus of Variations Course code FMAN25 ECTS credits 7.5 hp Year 202324 Study period the course was finishedVT_LP2 Programme all Registrated students 37 Number answers and response rate 5 / 14 % Number answers from males 2 Number answers from females 2 Study hours acco
https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2024/MATC25FMAN25VT24.pdf - 2026-06-27
Most of the γglutamyltransferase occurring in semen was found to be bound to the membranes of prostatic organelles, as is the case with Mg+plus;-Ca+plus;-dependent ATPase, and Zn+plus;-dependent peptidase hydrolysing succinyl (alanine)3-paranitroanilide. Organelie-bound γglutamyltransferase was released in a water-soluble form by papain. Charge shift electrophoresis revealed the presence in semina
Plasmons are investigated in free nanoscale Na, Mg, and K metal clusters using synchrotron radiation-based x-ray photoelectron spectroscopy. The core levels for which the response from bulk and surface atoms can be resolved are probed over an extended binding energy range to include the plasmon loss features. In all species the features due to fundamental plasmons are identified, and in Na and K a
Electron beam optics (particle betatron motion) and trajectory (centroid secular motion) in the FERMI@Elettra free electron laser (FEL) are modeled and experimentally controlled by means of the ELEGANT particle tracking code. This powerful tool, well known to the accelerator community, is here for the first time fully integrated into the Tango-server based high level software of an FEL facility, t
Abundance and respiration of free and attached microorganisms were monitored during the decomposition of the seagrass Scirpus maritimus leaves in laboratory microcosms for 30 days. There was a clear succession between bacteria and heterotrophic flagellates during the course of the study. The beginning of the study (1-4 days) was characterized by higher rates of bacterial respiration, compared to t
