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For most applications trying to interpret the real world uncertainties will be an important factor to consider, which is also true for Life-Cycle Assessment used for estimating total environmental impact during the life-cycle of products, services, buildings, structures, roads etc. The construction and usage of infrastructure are major causes of emissions and energy use, thus making it even more i
Part of the justification for an integrated view of speech and gestures ( (( is their temporal coordination. Gestures generally coincide with or precede, but rarely follow lexical affiliate (McNeill, 1992). How synchrony impacts listeners remains less explored, despite potential relevance for video communication and virtual conversational agents. ERP studies suggest that temporal alignment affects
This thesis contributes to the quantitative finance literature and consists of four research papers.Paper 1. This paper constructs a hybrid commodity interest rate market model with a stochastic local volatility function that allows the model to simultaneously fit the implied volatility of commodity and interest rate options. Because liquid market prices are only available for options on commodity
The basic pathophysiology of TBI consists of an initial, primary injury including rapid deformation of brain tissue with destruction of brain parenchyma and blood vessels and acute loss of neuronal and glial cells. A key concept in the management of TBI is that not all cell death occurs at the time of primary injury; instead, a cascade of molecular and neurochemical secondary events occur during t
Abstract: HLA‐DR2 is negatively associated with insulin‐dependent diabetes mellitus (IDDM). The aim of the present study was to analyze DR2‐positive patients among 425 consecutively diagnosed unrelated Swedish children with IDDM and in 367 matched controls. HLA‐DRB, ‐DQA and ‐DQB were determined by Taq I restriction fragment length polymorphism analysis. Amplification by polymerase chain reaction
Design requires thoughtful application of methods to broaden ones understanding of the task and to generate alternative solutions in the form of possible futures in relation to the task. These kind of activities implies learning. In an interaction design course for undergraduate engineering students, we noticed that students gave little effort to the usage of the design methodologies taught, and n
Background: In patients on hemodialysis with end-stage renal disease there is an increasing interest in measuring both residual renal function (RRF) and quantity and quality of dialysis because insufficient dialysis gives higher mortality. For that purpose we have measured clearances of two urographic iodine (I) contrast media (CM) with different molecular masses (iohexol 821 u and iodixanol 1,550
This dissertation investigates the reception of ancient Greek religion (and to some extent also renaissance Platonism) among contemporary Pagans in Greece - a phenomenon the author refers to as contemporary Hellenic polytheism. The study looks at how and why historical narratives and notions of Hellenicity are constructed by contemporary Hellenic polytheists. Furthermore it describes the contempor
From a strict technological perspective copyright holders can today truly enforce their rights ex ante by creating closed environments in which the consumption of digital works is strictly controlled by DRM systems. The scope of such control is however usually attributable to a given business model rather than legal compliance because the copyright framework (and particularly Art. 6 InfoSoc Direct
Current land use and climate change pose a threat to the continued provision of ecosystem services expected from terrestrial land cover. Studies on past land-cover responses to such changes provide valuable information for future decisions. The hemiboreal zone, situated between temperate and boreal biomes, is a natural sensitivity hotspot for land cover change: it contains a continuous distributio
Objective: To evaluate asynchronous digital visits (eVisits) with regard to digital communication, clinical decisionmaking,and subsequent care utilization in the digital era of primary care in Sweden.Methods: A mixed-methods approach was adopted across the various papers in the thesis, with all studiesevaluating the eVisit platform Flow in various clinical contexts.- Paper I was a comparative stud
The cosmogenic radionuclides 7Be and 10Be are useful tracers for atmospheric transport studies. Combining 7Be and 10Be measurements with an atmospheric transport model can not only improve our understanding of the radionuclide transport and deposition processes but also provide an evaluation of the transport process in the model. To simulate these aerosol tracers, it is critical to evaluate the in
During the last decades, more and more devices have been connected to the Internet.Today, there are more devices connected to the Internet than humans.An increasingly more common type of devices are cyber-physical devices.A device that interacts with its environment is called a cyber-physical device.Sensors that measure their environment and actuators that alter the physical environment are both c
Abstract – Introduction: Stroke is a leading cause of morbidity and mortality globally, with Africa bearing a disproportionately high burden of poor outcomes. In sub-Saharan Africa, acute stroke care remains inconsistent, with organized stroke units being either absent or rarely available, contributing to the high stroke mortality rates in the region. To address this issue, the Tanzania Stroke Pro
BACKGROUND: Variability of brain amyloid burden across individuals suggests that biological factors may play a role. This study investigates the association between polygenic risk scores (PRS) and amyloid burden in a preclinical Alzheimer's disease (AD) cohort to identify genetic determinants. METHOD: PRS for AD susceptibility (Kunkle et al., 2019) and for CSF-Aβ42 and ptau181 (Jansen et al., 2022
Background: We hypothesised that observed annual incidence rates of ANCA-associated vasculitis (AAV) are driven bysporadic short-term, high-intensity rates characterised as clusters of diagnosis events in time. Using data from Ireland, Swedenand Spain, we performed a changepoint analysis to discover time intervals with high and low rates of vasculitis diagnosis.Methods: We recruited 417 patients f
Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete, uns
