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Between 1982 and 2009 a total of 92 patients with myelofibrosis (MF) in chronic phase underwent allo-SCT in nine Nordic transplant centers. Myeloablative conditioning (MAC) was given to 40 patients, and reduced intensity conditioning (RIC) was used in 52 patients. The mean age in the two groups at transplantation was 46 +/- 12 and 55 +/- 8 years, respectively (P<0.001). When adjustment for age dif
BACKGROUND: IVF children, including singletons, are known to have a poorer obstetric outcome than children born after spontaneous conception. With a broad introduction of single embryo transfer (SET), this scenario might change. This study compares the obstetric outcome after IVF with SET, elective SET (eSET), non elective SET (non-eSET) and double embryo transfer (DET) with outcomes in the genera
Forest fires are one of the main disturbance agents in boreal and temperate ecosystems. To decipher large-scale temporal and spatial patterns of past fire activity in Scandinavia, we analysed the synchronicity of dendrochoronologically reconstructed fire events in a large network of sites (n=62; 3296 samples, 392 individual fire years) covering a wide geographical gradient (56.5-67.0 degrees N and
Popular Abstract in Swedish Sexuella övergrepp väcker starka känslor hos oss. Ibland tycks känslorna bli så svåra att vi försöker utestänga den plågsamma verkligheten genom att "blunda" för faktum. För att studera hur människor handskas med förekomsten av ett sexuellt övergrepp på ett barn i en bild, framställdes en bild, som avsåg att visa ett sådant övergrepp. Bilden visades för ett stort antal This investigation comprises five studies of factors determining adults' interpretations of a picture (Threat), drawn to represent sexual abuse of a child. The sexes of the two persons in the picture were on purpose drawn ambiguously. In Study I, the Threat picture was interpreted by 515 undergraduates in three experiments, all resulting in the same four interpretation categories, and similar freq
Wireline communication is the Internet access technology with the largest number of subscribers worldwide. On physical-layer level, the traditional way to transmit signals at one end of a wire pair and to extract receive signals at the other end is to apply differential-mode signalling: transmit and receive signals correspond to voltage differences between the two wires. Differential-mode signalli
Popular Abstract in Swedish Nervsignaler som förmedlar känsel från huden och kommandon till kroppsmuskulaturen passerar genom ryggmärgen eller dess motsvarighet i hjärnstammen. Kunskap om hur ryggmärgens nervkretsar är uppbyggda och hur de bearbetar nervsignaler är därför av fundamental betydelse för att kunna förstå och behandla exempelvis smärta och ryggmärgskador. I detta avhandlingsarbete studPrinciples for sensorimotor transformation and plasticity in the spinal cord and functional repair in the root-avulsed spinal cord were studied. A comparative study confirmed that the nociceptive withdrawal reflex (NWR) system is composed of reflex modules, with each performing a finely tuned transformation of skin sensory input to activity in one muscle. This suggests that modularity of the NWR s
This thesis comprises ecological, morphological and physiological studies of the carrot psyllid Trioza apicalis (Homoptera: Psylloidea) with particular focus on olfaction. Data from inventories of winter habitats suggest that T. apicalis prefer Picea abies over Pinus sylvestris and Juniperus communis as winter hosts. Their migration range is at least I km, and we found no clear wind-borne pattern
The production of methane via anaerobic digestion of agricultural residues and industrial wastewater would benefit society by providing a clean fuel from renewable feedstocks. This would reduce the use of fossil-fuel-derived energy and reduce environmental impact, including global warming and pollution. Limitation of carbon dioxide and other emissions through emission regulations, carbon taxes, an
Popular Abstract in Swedish Mitt försöksmaterial utgjordes av Festuca ovina, fårsvingel, som är ett mycket vanligt gräs och tillhör familjen Poaceae. Fårsvingel är en perenn korsbefruktare och spridd över den tempererade zonen i Euroasien och Nordamerika. Släktet Festuca är uppdelat i smalbladiga svinglar, dit fårsvingel hör, och bredbladiga svinglar. Släktet Lolium, dit rajgrFestuca ovina, sheep's fescue is a widely distributed perennial outbreeder that belongs to the grass family Poaceae and is very common in the northern temperate zone. The genus Festuca s.l. is partitioned into fine-leaved fescues to which F. ovina belongs, and broad-leaved fescues to which the genus Lolium is a close relative. Wide crosses within the Festuca-Lolium
Popular Abstract in Swedish Undersøkelsen omfatter 44 skandinaviske personer med Laurence-Moon-Bardet-Biedl syndrom. Disse personer hadde netthinne degenerasjon og minst ytterligere 2 av de øvrige tradisjonelle tegn på lidelsen: overvekt, overtallige fingre og tær, mangelfullt utviklede kjønnsorganer og nedsatt intelligens. Undersøkelsen viste at pasientene fikk nattblindhet og avtagende syn i barThe study included 44 Scandinavian individuals with the autosomal recessive inherited Laurence-Moon-Bardet-Biedl syndrome. Inclusion criteria were retinal dystrophy plus at least 2 more of the remaining traditional cardinal signs of the syndrome: obesity, polydactyly, hypogenitalism and mental retardation. The study showed that the patients had an early onset of night blindness and a poor visual p
The principles of mutual trust and mutual recognition are well established features of EU law. On a technical level, it is clear that the principles may require adoption of foreign levels of protection in individual cases as well as in legislation. At a closer look, however, the principles through “the rule of reason” also may imply quite the opposite: the imposing of domestic requirements on fore
BACKGROUND: It is estimated that global dementia rates will more than triple by 2050 and result in a staggering economic burden on families and societies. Dementia carries significant physical, psychological and social challenges for individuals and caregivers. Informal caregiving is common and increasing as more people with dementia are being cared for at home instead of in nursing homes. Caregiv
Vissa ungdomar som upplevt potentiellt traumatiserande händelser kan utveckla dissociationssymptom. Under gynnsamma förhållanden har människor en förmåga att integrera känslor, tankar, sinnesintryck och minnen av livshändelser in i en adaptiv och sammanhängande självbild och berättelse om självet. Dissociation i samband med trauma kan beskrivas som ett sammanbrott av denna förmåga. Dissociativa upAfter experiencing potentially traumatic events (PTEs) some adolescents develop pathological dissociation. Trauma-related dissociation can be described as a break-down of the individual’s capacity to integrate emotions, thoughts, sensations, and memories about traumatic or other events into an adaptive and coherent self-image and self-narrative. Dissociative experiences (DE) include experienced lo
Precipitation can be quantified using a rain gauge network, or a remotely sensed precipitation product. Ultimately, the choice of dataset depends on the particular application, the catchment size, climate and the time period of study. In a region with a long record and a dense rain gauge network, the elevation-modified ground-based precipitation product, PRISM, has been found to work well. However
Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient
Background: Human milk is a complex fluid comprised of myriad substances, with one of the most abundant substances being a group of complex carbohydrates referred to as human milk oligosaccharides (HMOs). There has been some evidence that HMO profiles differ in populations, but few studies have rigorously explored this variability. Objectives: We tested the hypothesis that HMO profiles differ in d
In the relations between states interpretation of treaties is an everyday issue. When an agent of state confers a meaning on a treaty text, the ensuing interpretation is talked of as being legally either correct or incorrect. This is a distinction made possible thanks to the existence of certain norms. These are the norms which find expression in the 1969 Vienna Convention on the Law of Treaties,
Introduction and aims. Mental disorders among perpetrators of violent and sexual crimes differ from those in the general population in prevalence, course, and patterns of comorbidity. The Göteborg Forensic Neuropsychiatry Projects was initiated to map neuropsychiatric vulnerability factors (disorders, deficits, symptoms, and neurobiological aberrations) among violent offenders and analyze the find
Popular Abstract in Swedish PAX FÖR MANETER! Evolutionen är den process som format det liv vi ser omkring oss. Ända sedan Darwins tid har man känt till att arter och djurgrupper uppstår genom att det finns en variation mellan individer och att då tillgångarna begränsas (såsom mat eller utrymme) blir det de bäst anpassade som överlever och fortplantar sig. Flercelliga djur har funnits på jorden i kDuring the course of evolution animal complexity and diversity is generated. The last couple of years it has become increasingly clear that morphologically diverse animals share a great deal of their genomic contents, and it must be the expression of regulatory genes in new setting, rather than the generation of new genes, that are fundamental for the generation of diversity. Basal phyla hold a ke
Aim: A correct diagnosis of coeliac disease, one of the most common chronic diseases in Swedish children, demands small bowel biopsy, which can be performed endoscopically or by means of a peroral capsule. Recently there was a debate among Swedish paediatric gastroenterologists, with some advocating the cessation of capsule biopsy in favour of endoscopic biopsies. To gain information on which to b
