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The exocrine pancreatic insufficient (EPI) pigs grow less due to different disturbances in feed digestion, absorption, and retention. Use of pancreatic-like enzymes of microbial origin in pigs may improve feed use and performance in slow-growing pigs. The aim was to study gut recovery and effectiveness of pancreatic-like enzymes of microbial origin supplementation on pig performance. Six male pigs
Popular Abstract in Swedish I plan to add a summary in Swedish at the WWW-page www.biokem.lu.se/education/theses/johannordthesis.htmRecombinant dUTPase from the bacterium Escherichia coli, the retrovirus equine infectious anemia virus (EIAV) and Homo sapiens have been made available for physico-chemical characterisation. The protocols developed have also proven to be suitable for production of enzymes modified by isotope labelling or other methods. The improved accessibility of enzyme material has enabled the subsequent invest
We study Hamming versions of two classical clustering problems. The Hamming radius p-clustering problem (HRC) for a set S of k binary strings, each of length n, is to find p binary strings of length n that minimize the maximum Hamming distance between a string in S and the closest of the p strings; this minimum value is termed the p-radius of S and is denoted by varrho. The related Hamming diamete
AIM: To study the interaction between the human cysteine proteinase inhibitor, cystatin C, and proteinases of periodontitis associated bacteria. METHODS: Gingival crevicular fluid samples were collected from discrete periodontitis sites and their cystatin C content was estimated by enzyme linked immunosorbent assay (ELISA). The interaction between cystatin C and proteolytic enzymes from cultured s
Recent advances in laser technology, with the development of extremely short-pulse, high-intensity lasers, have opened doors to new areas in atomic physics. By focusing light from an intense, short-pulse laser into a gas jet, the emission of high-order harmonics of the laser frequency has been studied. The aim of this work has been two-fold: to better understand the underlying physics of the harmo
Popular Abstract in Swedish Hjärt-kärlsjukdomar är en ledande orsak av sjuklighet och dödlighet. Med hjälp av dagens moderna ultraljudsteknik är det möjligt att påvisa även begynnande, mycket diskreta kärlförändringar. En tidig upptäckt av dessa kan bli av betydelse för individens framtida hälsa. I ett antal studier har vi med hjälp av ultraljud undersökt kärlens styvhet och förmåga att vidgas (enCardiovascular disease (CVD) is one of the leading causes of mortality and morbidity. Early recognition of vascular changes, both structural and functional, may help to identify individuals at risk for CVD. Using modern ultrasound techniques – the echo-tracking technique for assessment of stiffness in large arteries and flow-mediated dilatation of the brachial artery as an indicator of endothelial
Popular Abstract in Swedish Fysiologiska och biokemiska processer i den levande kroppen kan studeras mha spårämnestekniken positronemissions tomografi (PET). Den bildgivande tekniken PET kräver radionuklider som sönderfaller genom att sända ut en positron. Positronen är antimateria till elektronen. När positronen har en mycket låg rörelseenergi och träffar på en elektron, ombildas deras vilomassorPositron emission tomography (PET) is a tracer technique used for quantitative in vivo studies of physiological and biochemical processes. Because of the use of positron-emitting radionuclides such as 11-C, 13-N, 15-O and 18-F, which are isotopes of the biologically ubiquitous elements, it is possible to label radiopharmaceuticals which trace biochemical processes precisely. In order to be able to
Growth conditions on acid soils may be hampered by low nutrient availability and phytotoxic Al (aluminium) concentrations. In this thesis I present my studies on adaptation mechanisms of wild plants to acid soils in the close root environment, the rhizosphere. The studies showed that plants have developed several mechanisms that may work simultaneously to face the complex soil chemistry. A first g
Objective To assess intraobserver and interobserver variability in ovarian volume and gray-scale and color flow index measurements using transvaginal, three-dimensional, power Doppler ultrasonography. Methods Eleven women (22 ovaries) were examined on day 8 of controlled ovarian hyperstimulation therapy, which was part of their in vitro fertilization treatment protocol. The patients were examined
Popular Abstract in Swedish De flesta svenskar har nog upplevt hur skönt det kan värma i solen en klar vinterdag, trots att termometern visar minusgrader. Eller hur kallt det känns på ryggen en sommarkväll fastän man så sitter så nära en eld att det nästan bränns. Båda erfarenheterna beror på värmestrålning som kan värma oss utan att luften omkring oss är varm. Värmestrålningen från brasan når barInfrared (IR) dryers are widely used in the paper industry, mainly in the production of coated paper grades. The thesis deals with various aspects of heat transfer and energy use in infrared heaters and dryers as employed in the paper industry. Both gas-fired and electric IR dryers are considered and compared. The thesis also provides an introduction to infrared heaters and infrared drying, includ
Popular Abstract in Swedish Döva barns begreppsbildning i matematik Denna studie tar utgångspunkt i frågan varför många döva barn har svårt att lära sig matematik. Studiens syfte är att belysa döva barns begreppsbildning i ämnet matematik genom att beskriva hur några döva barn uttrycker sig och agerar på väg mot förståelse av två centrala matematiska begrepp, nämligen multiplikation med heltal ochThe question why deaf children have difficulties in learning mathematics is the basis of this study. The aim of the study is to illuminate deaf children’s concept formation in mathematics by describing how some deaf children express themselves and act on their way towards understanding two basic concepts, the concept of multiplication with whole numbers and the concept of length. Theories develope
Maternal hormones can have substantial phenotypic effects in the progeny of many vertebrates. It has been proposed that mothers adaptively adjust hormone levels experienced by particular young to optimize their reproductive output. In birds, systematic variation in egg hormone levels has been related to different female reproductive strategies. Because in many bird species prospects of the offspri
Recently, several articles have been published dealing with the anabolic effects on bone by statins. Mundy and associates discovered that several statins were able to activate the promotor of bone morphogenetic protein (BMP) 2. Additionally, oral simvastatin and lovastatin increased the cancellous bone volume in rats, presumably an effect of the increase of BMP-2. Other studies have followed, with
Aim: The main aim of the study was to describe the differences between some Northern countries regarding what foods, according to the patients, elicit hypersensitivity symptoms. Methods: At the participating clinics, patients with a history of food hypersensitivity (n = 1139) were asked to fill in a questionnaire in which 86 different foodstuffs were listed. Skin-prick tests (SPT) were performed w
Evolutionary change results from selection acting on genetic variation. For migration to be successful, many different aspects of an animal's physiology and behaviour need to function in a co-coordinated way. Changes in one migratory trait are therefore likely to be accompanied by changes in other migratory and life-history traits. At present, we have some knowledge of the pressures that operate a
BACKGROUND: Use of a catheter-free, radio telemetric, oesophageal pH-monitoring system in paediatric clinical practice allows patients to follow a more normal physiological pattern of activities and causes less discomfort. At our institution, placement of the capsule is done under general anaesthesia, which restricts the child's activity during the first day. The aim of this study was to determine
Aims/hypothesis Among diabetic patients, glucose homeostasis may be affected by abnormal gastrointestinal motility and autonomic neuropathy. This study analysed whether oesophageal dysmotility, delayed gastric emptying or autonomic neuropathy affect glucose homeostasis. Materials and methods Oesophageal manometry and gastric emptying scintigraphy were performed in 20 diabetic patients. Heart-rate
Background: In several studies, patients with alcohol dependence treated with the opioid antagonist naltrexone have shown fewer relapses to heavy drinking than those receiving placebo. An interaction between the naltrexone effect and the type of psychological therapy has been observed. Methods: A 6-month, double-blind, placebo-controlled, parallel-group study was performed at 10 different investi
BACKGROUND: We have measured blood lead concentrations (B-Pb) in Swedish children, yearly since 1978. As reported previously, a substantial decrease of B-Pb was found for the period 1978-1994 (2440 children measured), as an effect of gradual reduction of lead in petrol. In another report focusing on the petrol-lead-free period 1995-2001, we noted that B-Pb seemed to stabilize at an average level c
Purpose/Aim: To explore changes in morphology and function in the rabbit retina after intravitreal high-dose injection of three commonly used VEGF inhibitors. Materials and methods: Forty-eight rabbits of mixed strain (6 months of age, body weight ≈ 3 kg) were randomized into four groups (n = 12). They were examined with full-field electroretinography (ERG) and with multifocal electroretinograph
