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Popular Abstract in Swedish Den här avhandlingen studerar olika statistiska metoder för att utvinna information som ligger dold i en serie av tal eller andra symboler, exempelvis bokstäver. En sådan serie kan innehålla slumpmässighet eller ha vissa mätbara statistiska egenskaper, men har även ett inneboende mönster, vilket vi är intresserade av. Vi kallar vanligtvis sådana serier för signaler, ochThis thesis examines sparse statistical modeling on a range of applications in audio modeling, audio localizations, DNA sequencing, and spectroscopy. In the examined cases, the resulting estimation problems are computationally cumbersome, both as one often suffers from a lack of model order knowledge for this form of problems, but also due to the high dimensionality of the parameter spaces, which

Purpose/Aim: To explore changes in morphology and function in the rabbit retina after intravitreal high-dose injection of three commonly used VEGF inhibitors. Materials and methods: Forty-eight rabbits of mixed strain (6 months of age, body weight ≈ 3 kg) were randomized into four groups (n = 12). They were examined with full-field electroretinography (ERG) and with multifocal electroretinograph

Historically, minority rights have played a role in conflict prevention. The current situation in the West, where it is asserted that Islam is not compatible with democracy and Western values, lends itself to the application of such rights. The maintenance of Muslim group identity is a crucial factor, if the Muslim communities are to feel integrated and accepted in Western society. However, it is

Bilindustrin är en oligopolmarknad där de tio största tillverkarna står för 80% av världens totala produktion. De stora marknaderna Europa, Japan och Nordamerika har stagnerat och stabiliserats, vilket har förändrat branschen till en med höga fasta kostnader och låga marginaler. Försöket att öka marginalerna och anpassa sig till den japanska teorin “lean production” med kort ledtider i fabriken leThe automotive industry is an oligopoly and the ten largest manufacturers account for close to 80% of the overall global production. The major markets of Europe, Japan and North America, have stagnated and remain stable and this has transformed the industry into a business of high costs and low margins. Somewhat ironically, as an attempt to increase the margins and adapt to the Japanese theory of

Autopsy data indicate that the locus coeruleus (LC) is one of the first sites in the brain to accumulate hyperphosphorylated tau pathology, with the rostral part possibly being more vulnerable in the earlier stages of the disease. Taking advantage of recent developments in ultra-high field (7 T) imaging, we investigated whether imaging measures of the LC also reveal a specific anatomic correlation

Background: Children with right ventricular outflow tract (RVOT) anomaliestypically undergo surgical repair during their first months of life and thereafter they will need one or more reoperations through their life.Aims: The overall aim was to describe health-related quality of life (HRQoL) forchildren with congenital heart disease (CHD) with a special focus on children withRVOT anomalies and to

“There is something to confess: your speaker likes to leave a movie theater. Back out on the more or less empty, more or less brightly lit sidewalk (it is invariably at night, and during the week, that he goes), and heading uncertainly for some café or other, he walks in silence (he doesn’t like discussing the film he’s just seen), a little dazed, wrapped up in himself…”In his 1975 essay, Leaving

In a non-negligible number of patients with metastatic colorectal cancer (mCRC), the peritoneum is the predominant site of dissemination. Cure can be achieved by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), but this procedure is associated with long-term morbidity and high relapse rates. Thus, there is a pressing need for improved therapeutic strategies and co

BACKGROUND: First-in-human studies to test the efficacy and safety of human embryonic stem cells (hESC)-derived dopaminergic cells in the treatment of Parkinson's disease (PD) are imminent. Pre-clinical studies using hESC-derived dopamine neuron transplants in rat models have indicated that the benefits parallel those shown with fetal tissue but have thus far failed to consider how ongoing L-DOPA

During the last decade it has been increasingly acknowledged that carbon (C) contained in root exudates can accelerate decomposition of soil organic matter (SOM), a phenomenon known as rhizosphere priming effect (RPE). However, the controlling factors and the role of different soil microorganisms in RPE are not yet well understood. There are some indications that the response of the soil microbial

Children are particularly sensitive to air pollution exposure, and their personal exposures may differ significantly from those of adults. One key factor for understanding the personal inhaled dose of air pollutants is the respiratory minute ventilation (Ve). To estimate the amount of particles circulated through the lungs, 24 h averages of Ve are often used. These averages poorly capture variatio

Background: Life-space mobility is defined as the ability to access different areas extending from the room where the person sleeps to places outside one’s hometown. Life-space mobility is vital to support performance of daily life activities and autonomous participation in social life. However, there is a dearth of research that investigates a wider range of physical functions and functioning in

BACKGROUND: Tuberculosis (TB) is a major public health problem. Its magnitude the required interventions are affected by changes in socioeconomic condition and urbanization. Ethiopia is among the thirty high burden countries with increasing effort to end TB. We aimed to describe the case notification rate (CNR) for urban tuberculosis (TB) and estimate the percentage of TB patients who are not from

The ATLAS experiment at the Large Hadron Collider (LHC) employs a trigger system consisting of a first-level hardware trigger (L1) and a software-based high-level trigger. The L1 muon trigger system selects muon candidates, assigns them to the correct LHC bunch crossing and classifies them into one of six transverse-momentum threshold classes. The L1 muon trigger system uses resistive-plate chambe

This thesis asks when and why interest groups influence political parties. I address this question in two ways: 1) by examining the organizational ties between parties and interest groups, given that party-interest group ties may constitute an important step on groups' way to influence, and 2) by more directly examining interest group influence on parties. By doing this, the thesis contributes to

PD-L1 expression assessed by immunohistochemical staining is used for the selection of immunotherapy in non-small cell lung cancer (NSCLC). Appropriate validation of PD-L1 expression in cytology specimens is important as cytology is often the only diagnostic material in NSCLC. In a previous study comprising two different cohorts of paired biopsies and cytological specimens, we found a fairly good

BACKGROUND: The HIV epidemic in Ethiopia is concentrated in urban areas. Ethiopia conducted a Population-based HIV Impact Assessment (EPHIA) in urban areas between October 2017 and April 2018 to measure the status of the country's response to the epidemic.METHODS: We conducted field data collection and HIV testing in randomly selected households using the national, rapid testing algorithm with lab

Infections by pathogenic microorganisms remain one of the most serious concerns in several areas, particularly in hygienic applications. Antimicrobials have been used to combat these infections. Using small molecular antimicrobials as additives or coatings is an industrially adopted strategy. However, small antimicrobial agents always suffer from many drawbacks, such as leaching potential, toxicit

Background: The aim of the study was to demonstrate the safety and effectiveness of a suture-mediated vascular closure device to perform hemostasis after an axillary artery access during endovascular procedures on the aortic valve, the aorta and its side branches. Methods: A physician-initiated, international, multicenter, retrospective registry was designed to evaluate the success rate (VARC-2 re

Light is a key factor in poultry production; however, there is still a lack of knowledge as to describing the light quality, how to measure the light environment as perceived by birds, and how artificial light compares with the light in the natural forest habitats of their wild ancestors. The aim of this study was to describe the light environment in broiler breeder houses with three different lig