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Susceptibility to adversarial examples is one of the major concerns in convolutional neural networks (CNNs) applications. Training the model with adversarial examples, known as adversarial training, is a common countermeasure to tackle such attacks. In reality, however, defenders are uninformed about how adversarial examples are generated by the attacker. Therefore, it is pivotal to utilize more g
BACKGROUND: ATOR-1017 (evunzekibart) is a human agonistic immunoglobulin G4 antibody targeting the costimulatory receptor 4-1BB (CD137). ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.METHODS: In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to pati
Developing bones can be severely impaired by a range of disorders where muscular loading is abnormal. Recent work has indicated that the effects of absent skeletal muscle on bones are more severe early in development, with rudiment length and mineralization lengths being almost normal in muscle-less limbs just prior to birth. However, the impact of abnormal mechanical loading on the nanoscale stru
Background: Gestational diabetes is one of the most common pregnancy complications, affecting 14% of all pregnancies globally, and its prevalence is increasing. Gestational diabetes is associated with short and long-term complications for both the mother and their offspring, which are possible to prevent by glycemic control mainly facilitated by healthy lifestyle behaviors. Hence, women diagnosed
In recent years, the study of body image shifted from focusing on the negative aspects to a more extensive view of body image. The present study seeks to validate a measure of positive body image, the Body Appreciation Scale-2 (BAS-2; Tylka & Wood-Barcalow, 2015a) in Denmark, Portugal, and Sweden. Participants (N = 1012) were adolescents and young adults aged from 12 to 19. Confirmatory factor
BACKGROUND: Ventilator-associated pneumonia (VAP) is the most common intensive care unit-acquired infection, yet its diagnosis is complicated by the lack of reliable diagnostic criteria and validated biomarkers. Due to the compartmentalisation of the immune response, host proteins in respiratory tract samples are more likely than serum proteins to accurately identify VAP. However, a reliable bioma
The Swedish response to the pandemic at the national level has attracted considerable international attention, but little focus has been placed on the way municipalities dealt with the crisis. Using Hay's dimensions of politicization, namely the capacity for human agency, deliberation in the public domain, and social context, we analyze the politicization of the municipal response to the pandemic
How does parental social status affects child status attainment across time? Social mobility studies have traditionally studied parent-child associations using one ‘dominant’ parent to reflect social origin. However, the institutions of family and work have changed substantially over the past 150 years, in Sweden as elsewhere. These changes are associated with changes in intergenerationalstatus mo
Biogenic volatile organic compound (BVOC) flux dynamics during the subarctic autumn are largely unexplored and have been considered insignificant due to the relatively low biological activity expected during autumn. Here, we exposed subarctic heath ecosystems to predicted future autumn climate scenarios (ambient, warming, and colder, dark conditions), changes in light availability, and flooding, t
Rabi oscillations are periodic modulations of populations in two-level systems interacting with a time-varying field 1. They are ubiquitous in physics with applications in different areas such as photonics 2, nano-electronics 3, electron microscopy 4 and quantum information 5. While the theory developed by Rabi was intended for fermions in gyrating magnetic fields, Autler and Townes realized that
Background: A new, supposedly more reproducible radiographic classification, set to replace the Tönnis classification of hip dislocations, was proposed in 2015: the International Hip Dysplasia Institute (IHDI) classification. Purpose: To compare the IHDI classification with the Tönnis classification when evaluating the severity of hip dislocations as well as their respective inter- and intra-obser
Radio for everyone? Passages in English and other languages in Swedish publicservice radioThis article focuses on Swedish public service radio (Sveriges Radio, SR) and howinterviews in languages other than Swedish are given in SR. In the article, the result of a close analysis of 42 hours of broadcasting from SR is presented. All in all, a dozen languages are identified; however, English clearly d
Radiocarbon dating is the gold standard in archeology to estimate the age of skeletons, a key to studying their origins. Many published ancient genomes lack reliable and direct dates, which results in obscure and contradictory reports. We developed the temporal population structure (TPS), a DNA-based dating method for genomes ranging from the Late Mesolithic to today, and applied it to 3,591 ancie
Our previous data-driven analysis of evolving patterns of islet autoantibodies (IAbs) against insulin (IAA), glutamic acid decarboxylase (GADA) and islet antigen 2 (IA-2A) discovered three trajectories characterized by either multiple IAbs (TR1), IAA (TR2), or GADA (TR3) as the first appearing autoantibodies. Here we examined the evolution of IAb levels within these trajectories in 2,145 IAb-posit
In the search for efficient test methods for distributed real-time systems, an experiment is conducted that investigates the impact on the lead-time required to identify, a defect, depending on what information is available. One group of experiment participants were given a system monitoring trace, while a control group were given node monitoring traces. The information made available in the two s
Introduction: Secondary stroke prevention depends on proper identification of the underlying etiology and initiation of optimal treatment after the index event. The aim of the NOR-FIB study was to detect and quantify underlying atrial fibrillation (AF) in patients with cryptogenic stroke (CS) or transient ischaemic attack (TIA) using insertable cardiac monitor (ICM), to optimise secondary preventi
Rationale: We recently demonstrated that patients with coronary artery disease (CAD) and obstructive sleep apnea (OSA) carrying the tumor necrosis factor-alpha (TNF-α) A allele had increased circulating TNF-α levels compared with the ones carrying the TNF-α G allele. In the current study, we addressed the effect of TNF-α (-308G/A) gene polymorphism on circulating TNF-α levels following continuous
Circular economy (CE) has been of utmost interest in the industry and research community in the preceding years. However, CE is still a nascent research field in the built environment context. As technological advances within CE are slowing, the incorporation of business models into the concept is deemed important to achieve the necessary transition. Circular business models within the built envir
Impact cratering is associated with extreme physical conditions with temperatures and pressures far exceeding conditions otherwise prevailing at the surfaces of terrestrial planets. As a consequence, shock-metamorphosed rocks contain unique deformation features such as planar deformation features in quartz, high-pressure mineral polymorphs and melted rock. While the physical conditions of formatio
Emulsification is the process of making stable mixture of two or more immiscible substances (typically oil and water). The product of this process, the emulsion, is found in various applications and industries such as food (milk and other dairy products, non-dairy alternatives, mayonnaise, salad dressing), cosmetics and pharmaceuticals (creams, lotions, intravenous medications), chemical (paints,
