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Given the evidence that the primary motor cortex (MI) consists of subpopulations of upper motor neurons tuned to different directional parameters of a motor movement, this study hypothesized that novel motor skill training involving either a bidirectional or more complex multidirectional tongue-typing movement should produce distinct training-related features of tongue MI neuroplasticity in humans
Objectives: Evidence regarding the efficacy and effectiveness of certolizumab pegol (CZP) in rheumatoid arthritis (RA) patients who have failed to respond to treatment with a tumour necrosis factor inhibitor (TNFi) is limited. The aim of this study was to describe the effectiveness and survival-on-drug of CZP in a real-life setting, both in TNFi-naive patients and in patients who had previously fa
Popular Abstract in Swedish Alla växter utsätts för någon form av stress i sin dagliga miljö. Till exempel råder det väldigt sällan optimala tillväxtförhållanden på en åker, där ogräsen konkurrerar, insekterna knaprar, svamparna frodas och olika näringsbrister kan råda, för att inte tala om de torra somrarna. Det är alltså troligt att en växt utsätts för ett flertal stressfaktorer samtidigt, vilke
Popular Abstract in Swedish Syftet med undersökningen är att beskriva de livsförändringsprocesser som blir nödvändiga då en person drabbas av kronisk sjukdom eller ett funktionshinder. Vad innebär det att drabbas av en kronisk sjukdom eller ett funktionshinder? Hur lär man sig leva med de nya livsvillkoren? Dessa frågor belyses utifrån intervjuer med kvinnor som drabbats av kronisk smärta (fibromThe aim of this thesis is to study the life-changing processes necessary when a person is faced with the demands caused by chronic illness or disability. As subjects for the study, women with chronic pain (fibromyalgi and myofascial pain syndrome), were chosen. Eighteen women active in working life were interviewed on two occasions, with an interval of two months. The women have been living with t
The aim of this investigation is to answer the question of why it is prima facie morally wrong to cause or contribute to the extinction of species. The first potential answer investigated in the book is that other species are instrumentally valuable for human beings. The results of this part of the investigation are that many species are instrumentally valuable for human beings but that not all sp
Popular Abstract in Swedish En av tre svenskar drabbas av cancer. Hälften av de som behandlas för sin cancer får strålbehandling som en del av sin behandling. Teknikutvecklingen gör att strålbehandling kan levereras på mer och mer avancerade sätt. Det är dock svårt att veta vilka patienter som verkligen gynnas av behandling med en avancerad teknik och i så fall med vilken typ av avancerad teknik. Radiotherapy is one of the major tools for treating cancer. Through research and technical development radiotherapy is becoming more advanced with new treatment techniques emerging. In the work presented in this thesis, well-known methods have been used, or modified for use, and new methods have been introduced in order to optimise the clinical use of an advanced radiotherapy treatment technique,
This document Developing Emission Scenarios to aid Air Pollution Prevention and Control: A guideline manual for RAPIDC in South Asia has been written as a general introduction to the generation and utilisation of scenarios in a specific context. That context encompasses deliberate action to reduce the generation and impacts of air pollution. Thus, the work is intended to support the implementation
Background and Objectives. Osteopontin (OPN) is a non-collagenous matrix protein produced by various cells including osteoblasts, osteoclasts and several types of tumor cells. It is involved in a number of physiologic and pathologic events including adhesion, angiogenesis, apoptosis, inflammation, wound healing and tumor metastasis. We wanted to investigate the potential role of OPN in multiple my
Popular Abstract in Swedish Det är känt att låg socioekonomisk position (t.ex., låg inkomst, kort utbildning) och civilstånd, (t.ex., ensamstående) kan försämra hälsan. Den sämre hälsan medför ett ökat sjukvårdsbehov, och i ett jämlikt samhälle borde därför sjukvårdsutnyttjandet vara större bland de med låg socioekonomisk position och bland de som är ensamstående. Av samma anledning bör en högre fBesides individual characteristics, people born in the same country may present a related pattern of health status and health care utilisation, perhaps because they share a number of socioeconomic and cultural characteristics in addition to their common geographic origin and language. Rather than using simple ethnical or geographical categories, we apply multilevel regression analysis with individ
The identification and quantification of 20 different polynuclear aromatic hydrocarbons (PAHs) in the fly ash from a pressurized fluidized bed (PFB) air gasification system based:on hot gas filtering were determined by GC-MS analysis. A comparison was made on the basis of the results from two different sets of experiments with varied gasifier feedstock. The first set included four experiments with
Popular Abstract in Swedish Cellerna i blodet har en rad skilda funktioner, såsom att transportera syre, levra blodet vid behov eller att på olika sätt delta i vårt immunförsvar. Alla blodets celler härstammar från en s k stamcell som har förmåga att genom en rad förändringar mogna ut till vilken typ av cell som helst i blodsystemet. Leukemi är en sjukdom som drabbar blodet och som uppstår p g a aAcute myeloid leukemia (AML) is commonly associated with balanced chromosomal translocations. Characteristically, these translocations lead to the fusion of two unrelated genes, resulting in the expression of an aberrant fusion protein. t(8;21) is one of the most common translocations found in patients with AML. It results in the expression of the chimeric protein AML1-ETO. AML1 is a transcription
One group of commonly found parasites in birds, for which fitness consequences and effects on life history traits have been much debated are Haemosporidian blood parasites. In a long term study population of great reed warblers Acrocephalus arundinaceus in Sweden, previous studies have shown that the Haemosporidian blood parasites are in their chronic phase during the breeding season and that the
To explore whether quantitative, three-dimensional measurements of meniscal position and size are associated with knee pain using a within-person, between-knee study design. We studied 53 subjects (19 men, 34 women) from the Osteoarthritis Initiative, with identical radiographic OA grades in both knees, but frequent pain in one and no pain in the other knee. The tibial plateau and menisci were ana
Gold-mineralized quartz veins at the Trenggalek district of the Southern Mountains Range in East Java, Indonesia, are hosted by Oligo-Miocene volcaniclastic and volcanic rocks, and are distributed close to andesitic plugs in the northern prospects (Dalangturu, Suruh, Jati, Gregah, Jombok, Salak, and Kojan) and the southern prospects (Sentul and Buluroto). The plugs are subalkaline tholeiitic basal
New and innovative retail models such as product-service-systems (PSS) seem to offer a promising solution for more sustainable shopping activities. However, the adoption rate of PSS remains to date regretfully low. With the aim to investigate this problem, the present thesis focuses on the rental fashion model of use-oriented PSS and examines emotions that consumers experience in this context, whe
Soft biological tissues and engineered hydrogels for biomedical applications are intrinsically multiphasic materials, consisting of solid, fluid and possibly fixed and mobile ions. Understanding their mechanical behaviour requires experimental methods and theoretical models that take their multiphasic nature into account and allow for quantification of material parameters related to the different
Society is facing numerous environmental challenges today and tomorrow. Several global, national, and regional frameworks and instruments are in place to battle the storm. The Regional Council in Scania works with environmental issues through different programs and methods. Miljövårdsfonden is one of these methods, where financial support is allocated to various external projects to further a posi
The Bogong moth Agrotis infusa is a long-distance nocturnal migrant whose navigational ability still remains only partly understood. They travel up to a thousand kilometres to the Australian Alps where they seek out the shelter of isolated cool alpine caves, thereby escaping the approaching summer heat of their breeding grounds. Once in the caves, they enter a state of dormancy over the coming sum
This thesis examines the interplay between gender and the perception of impoliteness in the Japanese workplace. Firstly, impoliteness is an area in sociolinguistics that discusses face-threatening acts, perceived in situations modified by different aspects, e.g. context and the gender of the interlocutors. Secondly, gendered language is another area within sociolinguistics which gained popularity
