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BACKGROUND: The increasing number of survivors after childhood cancer requires characterization of the late complications of these diseases and their treatment. We examined a large number of possible socio-economic late effects following treatment for acute lymphoblastic leukemia (ALL) in order to identify factors leading to a poor outcome. PROCEDURE: All individuals who had been diagnosed with AL
Many automated gating algorithms for flow cytometry data are based on the concept of unimodal cell populations. However, in this article, we show that criteria previously used to make decisions on unimodality cannot adequately distinguish unimodal from bimodal densities. We show that dip and bandwidth tests for unimodality, taken from the statistics literature, can do this with consistent and low
The Wilms' tumor gene 1 (WT1) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of WT1 associate with a poor prognosis. In mice, WT1 cooperates with the RUNX1/RUNX1T1 (AML1/ETO) fusion gene in the induction of acute leukemia, further emphasizing a role for WT1 in leukemia development. Molecular mechanisms for WT1 are, however, incompletely understood. Here, we identif
We investigate organizational members’ crisis sensemaking and construction ofresponsibility at the peak of a corporate scandal. We focus on those organizationalmembers, who are not directly involved in the scandal but are still affected by it, as theyare questioned about their collective and moral responsibility for being members of anorganization that has engaged in wrongdoing. Our study is based
The plasma levels of cystatin C, β2-microglobulin, beta-trace protein, retinol binding protein (RBP) and creatinine were determined in plasma samples from 111 randomly selected patients with eGFRcystatin C ≤ 60% of eGFRcreatinine and from 55 control patients with 0.9eGFRcreatinine ≤ eGFRcystatin C ≤ 1.1eGFRcreatinine (eGFRcystatin C ≈ eGFRcreatinine). The concentration ratios of cystatin C/creatin
OBJECTIVE: The mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to investigate whether the organ of Corti could be a target tissue for insulin signaling using auditory House Ear Institute-Organ of Corti 1 (HEI-OC1) cells
Almost time to move in to the newly renovated M Building Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och
https://www.lth.se/article/almost-time-to-move-in-to-the-newly-renovated-m-building/ - 2026-07-21
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska för spridning i fakultets- och institutionskanaler vid Lunds universitet. Nr 24 v 33 - 2020. Rektor hälsar alla välkomna till en hösttermin med fortsatt distans* Ur rektorsbloggen: ”Nu står en ny termin för dörren. Vi kommer återigen att kunna välkomna en del studenter på campus. Även om flera kurser fortsatt kommer att ges på distans
https://www.cec.lu.se/sites/cec.lu.se/files/lu-gemensamt_mejlutskick_nr_24-2020-v33.pdf - 2026-07-23
Pontus Roos var en kreativ och initiativrik person som var övertygad om att praktiska problem inom industri- och tjänstesektorn kunde dra nytta av avancerad ekonomisk analys. Fondens syfte är att årligen dela ut ett stipendium till en doktorand eller en ung forskare i nationalekonomi vid Lunds universitet. Pontus Roos, född den 31 januari 1953, och avliden allt för tidigt, den 13 december 2010, va
Green Information System (IS) has become an important topic in IT management research and practice in the last few years due to economic opportunities and increasing pressure from stakeholders. However, many private organizations fail to manage their environmental efforts in an adequate manner since they neglect the strategic aspects of this topic. This paper discloses the strategic relevance of G
Seminar date: 30th of May 2018 Course: BUSN79 Business Administration; Degree Project in Accounting and Finance Authors: Oskar Lundin & Valdemar Olin Supervisor: Johan Dergård Keywords: Management control, Professional service firms, Clash of Cultures, Motivational theory, Social psychology theory Purpose: The purpose of this study is to contribute to the knowledge of why the performance o
Inherited retinal degenerations, collectively termed retinitis pigmentosa (RP), constitute one of the leading causes of blindness in the developed world. RP is at present untreatable and the underlying neurodegenerative mechanisms are unknown, even though the genetic causes are often established. Acetylation and deacetylation of histones, carried out by histone acetyltransferases (HATs) and histon
This paper uses a choice experiment to study citizens' preferences for effort-sharing rules for reducing carbon dioxide emissions. For a given global cost and level of emission reduction, we study the willingness to pay for various rules that imply different distributions of the cost between EU, the US. China and Africa. The focus of this paper is on the use of two different treatments, one where
Through research and interviews with several experts and stakeholders during the study visit in Zabrze, Poland, the main sources of air pollution in Zabrze and potential areas of intervention were identified. The project focused on residential heating in Zabrze, as coal based heating systems were identified as the main contributor to air pollution in the city. An alternative heating system scenari
Laminins are basement membrane components that regulate a plethora of biological processes. Despite decades of research, the exact roles of laminins in different tissues and in organogenesis remain to be elucidated. Here, we investigated the function of laminin γ1 chain in heart, lung and other tissues by generating a mouse that lacks laminin γ1 in cells expressing SM22α (Tagln) (LMγ1 flox/SM22α C
