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OBJECTIVE - We assessed the association between A1C and cardiovascular diseases (CVDs) in an observational study of patients with type 1 diabetes followed for 5 years. RESEARCH DESIGN AND METHODS - A total of 7,454 patients were studied from the Swedish National Diabetes Register (aged 20-65 years, diabetes duration 1-35 years, followed from 2002 to 2007). RESULTS - Hazard ratios (HRs) for fatal/n
The Swedish Dementia Registry (SveDem) was developed with the aim to improve the quality of diagnostic work-up, treatment and care of patients with dementia disorders in Sweden.
Background: The majority of non-syndromic colorectal cancers (CRCs) can be described as a complex disease. A two-stage case-control study on CRC susceptibility was conducted to assess the influence of the ancestral alleles in the polymorphisms previously associated with nutrition-related complex diseases. Methods: In stage I, 28 single nucleotide polymorphisms (SNPs) were genotyped in a hospital-b
Background: Genome-wide association studies (GWAS) have emerged as a powerful approach for identifying susceptibility loci associated with polygenetic diseases such as type 2 diabetes mellitus (T2DM). However, it is still a daunting task to prioritize single nucleotide polymorphisms (SNPs) from GWAS for further replication in different population. Several recent studies have shown that genetic var
Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens
Anthracyclines and taxanes are active cytotoxic drugs in the treatment of early metastatic breast cancer. It is yet unclear whether addition of capecitabine to the combination of these drugs improves the treatment outcome. Patients with advanced breast cancer were randomized to first-line chemotherapy with a combination of epirubicin (Farmorubicin(A (R))) and paclitaxel (Taxol(A (R))) alone (ET) o
OBJECTIVE Growth hormone (GH) deficiency is associated with insulin resistance and diabetes. The aim of the current study was to determine incidence of diabetes during GH replacement therapy (GHRT) and the effect of GHRT on fasting plasma glucose concentrations and HbA(1c) in adult patients with GH deficiency. RESEARCH DESIGN AND METHODS-A total of 5,143 GH-deficient patients (male 49.9%; mean age
The key role of tropical forest belowground carbon stocks and fluxes is well recognised as one of the main components of the terrestrial ecosystem carbon cycle. This study presents the first detailed investigation of spatial and temporal patterns of fine root stocks and fluxes in tropical forests along an elevational gradient, ranging from the Peruvian Andes (3020 m) to lowland Amazonia (194 m), w
A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons,
In a population-based study on cobalamin status and incident fractures in elderly men (n = 790) with an average follow-up of 5.9 years, we found that low levels of metabolically active and total cobalamins predict incident fractures, independently of body mass index (BMI), bone mineral density (BMD), plasma total homocysteine (tHcy), and cystatin C. Cobalamin deficiency in elderlies may affect bon
BACKGROUND AND PURPOSE: Data on the prevalence and indicators of weight loss in population-based groups of stroke survivors are scarce. We aimed to find the predictors and indicators of weight loss >3 kg as a possible marker of malnutrition after stroke. METHODS: We registered weight at baseline, after 4 months, and 1 year later in 305 survivors from a population-based cohort of first-ever st
This master’s thesis investigates sustainability management within a fashion company and how a company could use the sustainability management tool the Higg Index 2.0 Brand and Retail Module to work towards its prioritised UN Sustainable Development Goals (SDGs). It is a comparative review of the two frameworks, the Index and the SDGs, from a life cycle analysis perspective. It also includes a cas
Achieving a sustainable Swedish industry will require better utilization of resources already available and already spent. Nationally, vast amounts of heat are released into the atmosphere and not made use of. If only a fraction of this energy could be exploited, the path to net zero emission society by 2045 would be thousands of tons worth of CO2 closer. In Sweden, 25% of excess heat delivered to
Regional offices grow of more and more importance for the interest representation in Brussels. This study involves what determines if a region takes lobbying actions, what mobilization variables are important for the performance and what lobbying strategy is supposed to be the most successful. The study is a case study on the regional mobilization within the development of the ‘EU Strategy for the
This research paper uses an explanatory sequential mixed method design to examine the factors influencing students' decision-making regarding their future and the impact of Brexit on these choices. The study aims to understand the interplay between various factors and Brexit's role in shaping students' decisions. Initially, quantitative analysis of the 2017 CPC-ONS-UUK SoGIS survey dat
I Sverige prövas flera tusen mål som handlar om vårdnaden över barn varje år. Oavsett om vårdnaden tillfaller den ena föräldern, den andra eller båda, innebär processen en livsförändrande situation för det barn som står i centrum. Barnets rätt att komma till tals och barnets bästa utgör två grundläggande rättigheter som stadgas i artikel 12 respektive artikel 3 i Förenta nationernas konvention om In Sweden, several thousand cases concerning child custody are adjudicated each year. Regardless of whether custody is awarded to one parent, the other, or jointly, the process represents a profound and often life-altering experience for the child at the center of the dispute. The child’s right to be heard and the principle of the child’s best interests constitute two fundamental rights. They are
Many companies have introduced initiatives to achieve environmental sustainability and improve the wellbeing of the producers. This is the goal of the Era of We – an online platform that strives to disrupt the current market practices, promote environmentally sound coffee production and empower farmers. This thesis explores the perceived power dynamics between different stakeholders and how are th
Syftet med uppsatsen är att undersöka hur amerikanska påståenden kring Irakiska massförstörelsevapen användes som övertalningsmedel innan och omedelbart efter invasionen av Irak 2003. Detta görs via en kvalitativ innehållsanalys. Analysen utgår från Jowett och O`Donnells teoretiska ramverk på tio punkter för analys av propaganda. Dessa operationaliseras och appliceras på källmaterialet. Källmateri
Climate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee
