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Plant-based ice cream and whipping cream are increasingly popular as sustainable alternatives to traditional dairy products. Their low fat content makes them much healthier than high-fat dairy products. However, achieving desirable texture and stability in plant-based desserts remains a challenge. This study investigated how different processing conditions (homogenization pressure, upstream/downst

Dryland ecosystems are important yet understudied sinks of carbon dioxide (CO₂) and methane (CH₄), and sources of nitrous oxide (N₂O). Hence, monitoring greenhouse gas (GHG) fluxes and their responses to climate change in these systems is increasingly important. This thesis investigates the potential of hyperspectral reflectance data (between 390 and 1750nm) to predict greenhouse gas fluxes during

This thesis explores arguments and styles of argumentation in favour of Scotland gaining independence and rejoining the European Union in the aftermath of the United Kingdom leaving the EU in 2020. Since a majority of Scots did not support Brexit, it has provided Scottish independence supporters with a unique opportunity to bolster their arguments in the political debate. The thesis is built on a

Over the past decade, the field of Inner Transformation for Sustainability has grown into a substantial and influential body of knowledge, providing much of the scientific foundation for the Inner Development Goals (IDGs). In this conversation, Professor Christine Wamsler and Tomas Björkman reflect on the current state of the field. They emphasize that any meaningful application of the IDG Guide r

Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor

Objectives To establish the prevalence of clinically significant chronic obstructive pulmonary disease (COPD) and relevant characteristics in individuals with a significant smoking history who are hospitalised for acute myocardial infarction (MI). Design Cross-sectional study. Setting Hospital inpatients at 8 European centres (7 in Sweden, 1 in the UK). Participants 518 men or women (302 in Sweden

Cognitive-behavioral therapy (CBT) with exposure and response prevention is the most empirically supported psychological treatment for obsessive–compulsive disorder (OCD). Healthcare organizations and practice guidelines recommending CBT for OCD typically rely on meta-analyses that usefully aggregate treatment outcome findings. However, a critical methodological aspect of meta-analyses is the pote

INTRODUCTION: Hospital-acquired bloodstream infections (HA-BSIs) are severe and require antibiotic therapy. In non-complicated BSIs, shortened therapy reduces side effects without compromising efficacy. The impact of shortened antibiotic therapy in HA-BSI critically ill patients without indication of prolonged therapy requires further evaluation. METHODS: Using the international prospective EUROBA

The objective of this investigation was to explore a hybrid application of Structural Equation Modelling (SEM) and Fuzzy-set Qualitative Comparative Analysis (FsQCA) to assess the impact of safety-related behavioural traits on the performance of bicyclists using a limited sample of data as a case study. These behavioural characteristics of cyclists are fundamental when specific cyclist groups are

Two major debates frame Arctic prehistory: the emergence of specialized maritime economies that support sedentism and growing socio-political complexity, and the role of these economies in the transition from Paleo-Inuit to Neo-Inuit traditions. This shift, originating in the Bering Strait, led to Thule Inuit dispersal across the Arctic, impacting Indigenous communities today. However, understandi

Background: We investigated the impact of time to adjuvant chemotherapy (AC) on survival after surgical resection (<8 weeks or 8–16 weeks) for patients with non-small cell lung cancer (NSCLC) by applying a target-trial emulation. Material and Methods: We used Swedish population-based healthcare registries to emulate a hypothetical target trial, with treatment arms of ‘initiate AC <8 weeks postoper

BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy

An integrated framework is introduced and applied to assess the health impact of airborne pollution with greater physiological relevance, moving beyond conventional exposure metrics. Measured particle number size distribution data was integrated with a regional respiratory tract deposition fractions to estimate total and alveolar deposited particle surface area concentrations. Land use regression

BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial

OBJECTIVES: Telehealth, the provision of healthcare through digital communication, has been proposed as a potential solution to meet the increasing demand for healthcare, particularly in the setting of the COVID-19 pandemic. Sweden has an established national telehealth service for triage and referral by phone (1177) since 2013 which has the potential to meet this increasing demand. However, littl

Background: Peritoneal recurrence (PREC) following nephrectomy for localized renal cancer (RCC) is rare. Our objective was to report a multicenter analysis of PREC to analyze incidence, treatment, survival and risk factors. Methods: Between 1987 and 2023, patients with PREC following radical or partial nephrectomy (PN) for localized RCC across ten European institutions (UroCCR, NKI, IRCCS, Foch an

Background: Patients with diabetes admitted to emergency care face a higher risk of complications, including prolonged hospital stays, admissions to the intensive care unit and mortality. Aim: To develop a machine learning (ML) model to predict 30-day mortality in patients with diabetes admitted to the emergency department (ED). Design and setting: A cohort study utilizing data from all nine ED’s

Background: Wrist osteoarthritis (OA) is mainly posttraumatic, affects younger individuals than other types of OA, and can lead to significant disability. The first-line treatment is patient education and exercise, but surgery may be considered if symptoms persist. A mini-invasive surgical approach for wrist OA is partial wrist denervation, which,in theory, alleviates pain by resecting sensory ner

This systematic review and meta-analysis of individual patient data evaluates the outcomes of treatment for Dupuytren's disease using limited fasciectomy (LF), percutaneous needle fasciotomy (PNF) and collagenase clostridium histolyticum (CCH) injection. A total of 1423 studies were identified, of which 15 met the eligibility criteria for meta-analysis. The postoperative total extension deficit wa