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A new particulate magnetic resonance (MR) contrast agent was prepared by controlled precipitation of iron oxide in an aqueous starch solution. The potential of the magnetic starch microspheres (MSM) as a hepatosplenic contrast enhancer was studied by MR spectroscopy and MR imaging. Intravascular administration of MSM to rodents showed an effective blood clearance and a tissue-specific localization
Popular Abstract in Swedish Jordens havsnivå förändras kontinuerligt. I ett längre geologiskt tidsperspektiv styrs förändringarna av processer i jordens inre, men i ett kortare tidsperspektiv spelar yttre processer, såsom tillväxt och avsmältning av inlandsisar, stor roll för havets nivåförändringar. Det grönländska istäcket är idag norra halvklotets enda inlandsis och dess tillväxt och avsmältninNew results are presented from the investigation of relative sea-level changes in the Nanortalik and Qaqortoq-Narsarsuaq areas in SW Greenland from c. 11 000 cal. years BP to the present. Isolation and transgression sequences from seven lakes and seven tidal basins are identified using some of the traditional methods such as stratigraphic description, magnetic susceptibility, saturated induced rem
Background: In most clubfoot studies, the outcome instruments used are designed to evaluate classification or long-term cross-sectional results. Variables deal mainly with factors on body function/structure level. Wide scorings intervals and total sum scores increase the risk that important changes and information are not detected. Studies of the reliability, validity and responsiveness of these i
A fluorescence lidar measurement has been performed on the castle Övedskloster in Sweden. A mobile system from the Lund University was placed at ~40 m distance from the sandstone façade. The lidar system, which uses a frequency-tripled Nd:YAG laser with a 355-nm pulsed beam, induces fluorescence in each target point. Areas were studied by using whisk-broom scans. The possibility of detecting biode
A new Reynolds stress transport model (RSTM) aimed for engineering applications is proposed with consideration of near-wall turbulence. This model employs the Speziale, Sarkar and Gatski (SSG) pressure strain term, the omega equation, and the shear stress transport (SST) model for the shear stresses at the near-wall region (say, y(+) < 30). The models are selected based on the following merits: Th
A disaccharide scaffold based on galabiose (Gal1–4Gal) was synthesized. Four different acceptors were evaluated in the -galactosylation and a relationship between the nucleophilicity, yield, and /-selectivity was found. The scaffold contains two orthogonal derivatisation sites, i.e. at O-2′ and the anomeric position, and as proof of concept, one derivatised galabioside was synthesized. Compounds b
Popular Abstract in Swedish Moderna tillverkningsmaskiner är dyra och därför måste dess tillgänglighet och effektivitet ständigt hållas högt. Sådana resultat kan man inte åstadkomma utan tillämpning av en effektiv underhållsstrategi. Förutsättningar för att minska eller arrestera förslitnings hastighet på maskins delar och öka maskinlivslängden är stora vid användning av tillståndsövervakning, (TÖModern machinery is expensive and therefore must run at high availability and effectiveness which cannot be achieved without an effective maintenance policy. Condition monitoring, (CM), techniques can be utilised to reduce or arrest the rate of deterioration of a component so increasing operating life. The main result reported in this thesis is that the rolling element bearing’s mean effective li
Specific granule protein of 28 kDa (SGP28), also termed cysteine-rich secretory protein 3 (CRISP-3), is a glycoprotein that belongs to a family of cysteine-rich secretory proteins (CRISPs). SGP28 was originally discovered in human neutrophils, but transcripts are widely distributed in exocrine glands (salivary glands, pancreas, and prostate) and also found at lower levels in epididymis, ovary, thy
The pharmacokinetics of antimigraine drugs zolmitriptan and sumatriptan varied considerably with a fourfold to 10-fold variation in plasma levels. In addition, the pharmacodynamics of triptans as investigated in vitro also varied considerably. In theory, there should probably be a 10-fold variation in doses available, but in clinical practice a fourfold difference in doses will probably cover the
Idiopathic Scoliosis is a spinal deformity affecting approximately 3% of otherwise healthy children or adolescents. The etiology is still largely unknown but has an important genetic component. Genome-wide association studies (GWAS) have identified a number of common genetic variants that are significantly associated with idiopathic scoliosis in Asian and Caucasian populations, rs11190870 close to
Despite the spatially homogenous summer temperaturepattern in Fennoscandia, there are large spreadsamong the many existing reconstructions, resulting in anuncertainty in the timing and amplitude of past changes.Also, there has been a general bias towards northernmostFennoscandia. In an attempt to provide a more spatiallycoherent view of summer (June–August, JJA) temperaturevariability within the l
We present an EBL-defined nanowire pattern that can sort axons coming from different directions on a substrate. The pattern defines tracks for left-bound traffic and right-bound traffic, which opens up new possibilities for designing neural networks on a chip.
A temporal filtering technique, complementary to spectral filtering, has been developed for laser-induced fluorescence measurements. The filter is applicable in cases where the laser-induced interfering signals and the signal of interest have different temporal characteristics. For the interfering-signal discrimination a picosecond laser system along with a fast time-gated intensified CCD camera w
Participants in an international conference on the management of haemophilia patients with inhibitors developed a jointly authored summary of the findings and conclusions of the conference. Current knowledge of the genetic and immunologic mechanisms underlying inhibitor development was briefly summarized. Concerning the purported treatment-related risk factors, conference participants commented on
Almost all Swedish politicans since 1960 honestly believe in the necessity to give pupils real influence over their schools. The first aim with this paper is to give them some sound theoretical support for their conviction that experience of democratic processes is one important precondition for the survival of democracy. The theoretical support is drawn from researchers inspired by Piaget's epist
Several different factors may determine where species range limits are located within regions of otherwise continuously available habitat and suitable climate. Within the Arctic tundra biome many bird species are migratory and their breeding distributions are affected by migration routes that are in turn limited by factors such as suitable winter habitat, migratory stopover sites, geographical bar
Information and Communication Technologies (ICT) have relevant positive and negative impacts on environmental sustainability on various levels: First-order effects such as increasing electronic waste streams; second-order effects such as improved energy-efficiency of production; third-order effects such as a product-to-service shift in consumption or rebound effects in transport. In the simulation
