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Vaginal natural orifice transluminal endoscopic surgery (NOTES) is a novel technique for minimally invasive gynecological surgery. Adequate training and standardization are key elements to patient safety and quality of care. Based on consensus statements and expert opinion; we report a step-by-step guidance for hysterectomy via natural orifice transluminal endoscopy. A detailed description is pres
The implementation of circular initiatives requires certain capabilities and knowledge that traditional business models often lack, requiring new perspectives and external collaborations. This paper explores the competency needs and partnership dynamics of established companies collaborating for business model innovation for circularity through a case study of a gap exploiter business model, a com
A model is presented that describes the reemergence of parent spruce bark beetles, Ips typographus, based on breeding density and temperature conditions. Laboratory data obtained at one constant temperature provide the distribution of reemergence time and different combinations of threshold temperatures and degreedays (°D) at mean reemergence. Of these combinations, 167.71 °D above 7.5 °C gave the
In this paper we provide a counterpoint to conventional views on integrative reviews in knowledge development, as exemplified by Elsbach and Van Knippenberg (2020). First, we critique their proposed integrative review by identifying and problematizing several key assumptions underlying it, particularly their idea that the integrative review can simply build on existing studies and lead the way to
Objective: To develop and externally validate prediction models for incident hand osteoarthritis (OA) in a large population-based cohort of middle aged and older men and women. Design: We included 17,153 men and 18,682 women from a population-based cohort, aged 35–70 years at baseline (1995–1997). Incident hand OA were obtained from diagnostic codes in the Norwegian National Patient Register (1995
Background The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation is routinely used to assess renal function but exhibits varying accuracy depending on patient characteristics and clinical presentation. The overall aim of the present study was to assess if and to what extent glomerular filtration rate (GFR) estimation based on creatinine can be improved.MethodsIn a cro
Background: Nine mRNA transcripts associated with acute cellular rejection (ACR) in previous microarray studies were ported to the clinically amenable NanoString nCounter platform. Here we report the diagnostic performance of the resulting blood test to exclude ACR in heart allograft recipients: HEARTBiT. Methods: Blood samples for transcriptomic profiling were collected during routine post-transp
We present a program to compute polarizabilities of nominal one-electron systems using the Lagrange-mesh method (LMM) (Baye, 2015), that was used by Filippin et al., (2018). A semiempirical-core-potential approach is implemented, ultimately solving a Dirac-like equation by diagonalizing the corresponding Hamiltonian matrix. In order to build the core potential, the core orbitals are obtained from
Background: Previous research shows that critical constructive feedback, that scaffolds students to improve on tasks, often remains untapped. The paper’s aim is to illuminate at what stages students provided with such feedback drop out of feedback processing. Methods: In our model, students can drop out at any of five stages of feedback processing: (1) noticing, (2) decoding, (3) making sense, (4)
Crowd models can be used for the simulation of people movement in the built environment. Crowd model outputs have been used for evaluating safety and comfort of pedestrians, inform crowd management and perform forensic investigations. Microscopic crowd models allow the representation of each person and the obtainment of information concerning their location over time and interactions with the phys
We present an approach for the estimation of ore processing residue volumes in historical mine waste dumps by the use of different geophysical methods in combination with mineralogical investigations. The stamp mill dump in the Harz mountains, Germany was examined with the methods electrical resistivity tomography (ERT), ground penetrating radar (GPR) and spectral induced polarization (SIP) flanke
The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host. In this review article, we give an overview of past and current efforts to restore damaged connectivity in the adult mammalian brain using implants of fetal neuroblasts or stem cell-derived neuronal precursors, with a focus on strategies aimed t
Full-field transmission X-ray microscopy (TXM) is a well established technique, available at various synchrotron beamlines around the world as well as by laboratory benchtop devices. One of the major TXM challenges, due to its nanometre-scale resolution, is the overall instrument stability during the acquisition of the series of tomographic projections. The ability to correct for vertical and hori
There is a large financial incentive to minimise operations and maintenance (O&M) costs for offshore wind power by optimising the maintenance plan. The integration of condition monitoring (CM) and structural health monitoring (SHM) may help realise this. There is limited work on the integration of both CM and SHM for offshore wind power or the use of imperfectly operating monitoring equipment.
The construction workflow of in-situ concrete frames in multi-storey residential buildings is highly complex and dynamic. Discrete-event simulation (DES) offers capabilities to model and analyse such complexity. Although DES has successfully been used by researchers in a wide range of construction-related applications there are not many examples demonstrating how different simulation outputs (time
Emergence agitation following anesthesia in children is not uncommon. It is, although generally self-limiting, associated with both patient and parents distress. We conducted a national survey around the management of behavioral and neurocognitive disturbances after surgery/anesthesia including a case scenario about a child at risk for emergence reaction. Premedication with clonidine or midazolam
Obesity is the main risk factor behind insulin resistance and type 2 diabetes. Still, the mechanism behind adipocyte dysfunction is not yet resolved. Recently, we reported that rapid actin remodeling correlates with adipose cell size changes after short-term overfeeding. Therefore, we hypothesized that the actin-driven myocardin-related transcription factor (MRTF-A) contributes to impaired mature
