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Popular Abstract in Swedish Autoimmuna sjukdomar är tillstånd där vårt immunförsvar angriper den egna kroppen. Det finns ett flertal sådana sjukdomar av vilka jag huvud-sakligen har intresserat mig för rheumatoid artrit (RA) och multipel skleros (MS). De behandlingar som finns för de drabbade är idag främst riktade mot ergonomi, smärtlindring och olika former av immunsupres-sion (tex TNFa antikropThe causes of autoimmune diseases are largely unknown today, but there is evidence supporting a substantial complex genetic influence on many of these diseases as well as environmental factors and chance. In this thesis I have tried to get one step closer to the genetic causes of two autoimmune diseases through their induced counterparts in mice, namely rheumatoid arthritis (RA) and multiple scler

This paper presents the implementation of a dual mode wavelet based R-wave detector for cardiac pacemakers. A previously published R-wave detector was developed for a noisy environment. This detector has been supplemented with a noise detector that operates in supervision mode, and automatically activates/deactivates 2/3 of the detector hardware without performance degradation. The noise detection

Global competition forces companies to constantly increase the efficiency in their production systems. One important factor affecting the production performance is the inbound materials handling system. When designing or relocating a manufacturing system, the cost of the material handling system is one of many things to take into consideration. In connection with on-going research a comprehensive

A recent study of ours suggested that the very presence of a Teachable Agent (TA) from a mathematics learning game might affect students’ test performance when the TA reappeared in the margin of a regular, digital math test. We hypothesized that this effect, which seemed to particularly target low-achievers, was due to the students’ mindset changing from that of “taking a test” to that of “teachin

Popular Abstract in Swedish Respiratorbehandling är nödvändig då en patient på grund av kronisk eller akut lungsjukdom inte själv kan upprätthålla ett adekvat gasutbyte. Bakomliggande orsaker kan vara kronisk obstruktiv lungsjukdom, lunginflammation, blodförgiftning eller trauma. Respiratorbehandling kan i sig orsaka ytterligare skador på redan sjuka eller skadade lungor. Bland de faktorer som harIncreasing attention is paid to mechanical ventilation as one cause behind aggravation of lung injury. Lung protective ventilation can be achieved e.g. by minimising tidal lung collapse and re-expansion and by the use of small tidal volume allowing some degree of permissive hypercapnia. The ventilator and the sick lung comprise a very complex system. Identification of a ventilator setting that wit

Ever since the end of the 1970s triple-pane windows have been ”standard” in new construction of dwellings and non-residential premises in Sweden. The background was the first oil crisis in 1973, which led to a dramatic sharpening of the thermal requirements regarding the thermal envelope of Swedish buildings. These were introduced in the new building code SBN 75 which was brought into practice in

Controlling an induction machine has been a difficult task since its invention, especially at low speed operation and during highly dynamic regimes, where the required torque/speed changes constantly. This paper aims to present the validation and implementation of a deadbeat direct torque and flux control scheme (DB-DTFC) for induction machines on a multilevel platform consisting on an FPGA, a rea

We investigate a model for buffer management of multi-class traffic into a finite shared buffer. A hierarchy of increasingly stronger linear programming relaxations for this model is proposed. The number of hierarchies equals the number of job classes. Each relaxation in the hierarchy is constructed by projecting the original achievable performance region into a polytope with fewer variables and f

When making nanoelectrodes for applications in liquid cells it is plausible that the less noble metal layer may be negatively affected, i.e. it will be etched away leading to very unstable conditions during operation. Here we describe a dry method to produce such a molecular layer consisting of mercaptopropyltriethoxysilane (MPTS) making it possible to controllable and reproducibly form a covalent

Abstract in UndeterminedIn today's technology generations, e.g. 90 and 65 nm, the static power consumption becomes a major contributor to the total power consumption. This paper focuses on the arithmetic level and shows a methodology for a substantial reduction of the static power consumption. Simulations are done in a typical 130 nm technology. Based on the simulation results, the static power in

A neutron transport system for the planned imaging instrument ODIN at the future European Spallation Source (ESS) based on neutron optical components was designed and optimized. Different ways of prompt pulse suppression were studied. The spectral performance of the optimal neutron guide configuration is presented. In addition, the influence of the gaps in the guide system needed for the required