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The detailed mechanisms of progressive intensification of seizures often occurring in epilepsy are not well understood. Animal models of kindling, with progressive intensification of stimulation-induced seizures, have been previously used to investigate alterations in neuronal networks, but has been obscured by limited recording capabilities during electrical stimulations. Remote networks in kindl

The adult frog dorsal root ganglia (DRGs) and their sciatic nerves (ScN) survive in organ culture for several days. About 3 days after a local test crush, the sensory axons start to regenerate into the distal nerve stump at a rate of approximately 0.6-0.9 mm/day. The axonal outgrowth is inhibited in a non-toxic way by low concentrations of three different phospholipase A2 (PLA2) inhibitors: 4-brom

Ozone oxidation of organic micropollutants in biologically treated wastewater was investigated in pilot-scale after a high- and a low loaded activated sludge process. Higher ozone doses were required to remove organic micropollutants in the effluent wastewater from the high loaded activated sludge process. Further comparison of the micropollutant removal was based on normalized ozone doses, expres

Voltage-gated Ca2+ (CaV) channels trigger glucose-induced insulin secretion in pancreatic beta-cell and their dysfunction increases diabetes risk. These heteromeric complexes include the main subunit alpha1, and the accessory ones, including subunit gamma that remains unexplored. Here, we demonstrate that CaV gamma subunit 4 (CaVγ4) is downregulated in islets from human donors with diabetes, diabe

Standing postural stability relies on input from visual, vestibular, proprioceptive and mechanoreceptive sensors. When the information from any of these sensors is unavailable or disrupted, the central nervous system maintains postural stability by relying more on the contribution from the reliable sensors, termed sensory re-weighting. Alcohol intoxication is known to affect the integrity of the v

This paper reports on research on the engagement of ISO 14001 certified companies in environmental supply chain management, the drivers and barriers that influence their involvement, and how these forces correspond to the internal environmental management activities. In parallel, the issues of internal capabilities of companies, crucial for companies to respond to such driving forces, are highligh

Whistle-blowing can serve as a powerful mechanism helping policy-makers and other stakeholders recognize ethical misconduct and other types of wrongdoing in autonomous public agencies. This mechanism is of particular importance in major public sector reforms, such as agency mergers, when it may be difficult to secure continuity in the quality of organizational processes. Yet, we know little of wha

This paper critically investigates the impact and meaning of managerialism in a pharmaceutical firm by exploring its shaky basis. Managers' explanations of the failure in research leading to new products showed considerable variety. This reflects the absence of any shared understanding of research inefficiencies and difficulties to determine the roots of the problems. Despite this people blame bad

A key to successful chronic neural interfacing is to achieve minimal glial scarring surrounding the implants, as the astrocytes and microglia may functionally insulate the interface. A possible explanation for the development of these reactions is mechanical forces arising between the implants and the brain. Here, we show that the difference between the density of neural probes and that of the tis

Co-selection for antibiotic tolerance in Cu polluted soils was studied in a laboratory experiment. Pollution Induced Community Tolerance (PICT) of the bacterial community was estimated using leucine incorporation. PICT was found in Cu polluted soils to tetracycline (>= 8 mmol Cu kg(-1)), tylosin (>= 16 mmol Cu kg(-1)) and vancomycin (>= 16 mmol Cu kg(-1)). PICT to the antibiotics was found at high

What would it be like if we said one thing, and heard ourselves saying something else? Would we notice something was wrong? Or would we believe we said the thing we heard? Is feedback of our own speech only used to detect errors, or does it also help to specify the meaning of what we say? Comparator models of self-monitoring favor the first alternative, and hold that our sense of agency is given b

This thesis describes how business can be improved using a number of rather new methods; Data Mining, Business Intelligence and Customer Relationship Management. The idea presented is that an organization, through data, owns a lot of information about their business and customers. In order to turn this information into knowledge, it needs to be interpreted. The knowledge acquired will improve the

The possibility to make environmental strategy a part of the core strategy through a framework called inside-out/outside-in was suggested by Porter in 2007. Researchers have also stated that the output of implementing a certain strategy ought to be valued during strategy planning. The two areas; environmental strategy and profitability analysis have although not frequently been combined, and thus

Denna uppsats syftar till att undersöka samspelet mellan principen om jämbördig suveränitet stater emellan och möjligheterna för rättslig prövning och verkställighet av mänskliga rättigheter. I synnerhet undersöks rätten till hälsa, såsom den redogörs för i International Covenant on Economic, Social and Cultural Rights. Uppsatsen innehåller en sammanfattning av suveränitetsteorin och dess klassiThis thesis seeks to examine the interplay of the theory of equal sovereignty between states and justiciability of human rights, in particular the right to health, as enshrined in the International Covenant on Economic, Social and Cultural Rights (ICESCR). The essay contains an overview of the theory of sovereignty, divided into its two main paradigms of thought, namely universalism and particula

The theme of this essay is to examine how prophet stories are presented for children. The specific aim is to analyze the narrative structure of two texts presenting the story of Adam. The study uses two Arabic children texts presenting the Story of Prophet Adam (pbuh). The study starts with presenting some theories and their typological frame of narratology and some of their narratological tools,