Filetype
In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming. However, the biological significance of this mechanism in vivo remains unclear. Here, we address mitotic retention of the hemogenic factors GATA2, GFI1B and FOS during haematopoietic specifica
Improvements in metabolite-profiling techniques are providing increased breadth of coverage of the human metabolome and may highlight biomarkers and pathways in common diseases such as diabetes. Using a metabolomics platform that analyzes intermediary organic acids, purines, pyrimidines, and other compounds, we performed a nested case-control study of 188 individuals who developed diabetes and 188
Objective. The association between smoking and idiopathic inflammatory bowel disease is well known; smoking seems to have a diverse effect. Crohn's disease is associated with smoking, while ulcerative colitis is associated with non-smoking. Data on smoking in microscopic colitis of the collagenous type (CC) are lacking. The aim of this investigation was to study smoking habits in CC and to observe
Popular science summary: Is RpS6 activation important for leukemia cell progression? Acute Myeloid Leukemia (AML) is the most common acute blood cancer in adults. It is characterized by a rapid increase of leukemic cells in the bone marrow, compromising the development of new blood cells. Despite improvement in treatments and advancements in supportive care, the overall 5-years survival of AML i
We prove that for k ≪ 4 n regular resolution requires length nΩ(k) to establish that an Erdős–Rényi graph with appropriately chosen edge density does not contain a k-clique. This lower bound is optimal up to the multiplicative constant in the exponent, and also implies unconditional nΩ(k) lower bounds on running time for several state-of-the-art algorithms for finding maximum cliques in graphs.
There is (or should be) an archived specimen, a reference copy if you like, for all living and fossil species that have been described scientifically. These physical specimens, so-called name-bearing type specimens, are housed at museums or academic institutes around the world for researchers to study and perhaps compare with their own material. But what about our own species, Homo sapiens?.
Pancreatic endocrine cell differentiation depends on transcription factors that also contribute in adult insulin and glucagon gene expression. Islet cell development was examined in mice lacking MafB, a transcription factor expressed in immature alpha (glucagon(+)) and beta (insulin(+)) cells and capable of activating insulin and glucagon expression in vitro. We observed that MafB(-/-) embryos had
The aim of this paper was to examine how useable and inclusive the city is from the perspective of older bicyclists. Methods used were quantitative questionnaires and qualitative focus group interviews. Participants were people aged 65 years or older. The results showed that respondents were fairly satisfied with the transport infrastructure design. However, other road users seemed to complicate c
In recent years, scientists have advocated the use of targeted therapies in the form of drugs that modulate genes and proteins that are directly associated with cancer progression and metastasis. Malignant melanoma is a dreadful cancer type that has been associated with the rapid dissemination of primary tumors to multiple sites, including bone, brain, liver and lungs. The discovery that approxima
The so-called Substituted Judgment Standard is one of several competing principles on how certain health care decisions ought to be made for patients who are not themselves capable of making decisions of the relevant kind. It says that a surrogate decision-maker, acting on behalf of the patient, ought to make the decision the patient would have made, had the latter been competent. The most common
During mammalian ocular development, several signaling pathways control the spatiotemporal highly defined realization of the three-dimensional eye architecture. Given the complexity of these inductive signals, the developing eye is a sensitive organ for several diseases. In this study, we investigated a Dkk1+/- haploinsufficiency during eye development, resulting in coloboma and anterior eye defec
Denna uppsats syftar till att undersöka hur nystartade SME:s ser på nyttjandet av molntjänster och om detta är implementerat i företagens IS strategi. Detta görs med hjälp av en sammanställning av litteratur kopplat till ämnet samt en empirisk datainsamling. Den empiriska datainsamlingen består av sju telefonintervjuer med SME:s. Företagen har valts ur ett urval som är avgränsat till företag som a
Schema Riskanalys inom natur, miljö och hälsa MVEC12 15 högskolepoäng, HT 2015 version 20150820 VECKA DATUM DAG TID TITEL Form Lärare Läs SAL HUS BLOCK V. 36 31-aug må 10-11 Upprop, Kursintroduktion S MH Mossen öster INTRODUKTION KURS 01-sep ti 10-12 Risker med nanopartiklar F MHE+MOK Mossen öster HÄLSA 02-sep on 9-12 Introduktion om biomarkörer och hälsostudier F CL+ML Mossen öster HÄLSA 13-15 Ri
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec12_schema_ht15_v2.pdf - 2026-07-10
Prel.Schema MVEN018 - Klimatstrategiska metoder Vårterminen 2019 OBS Alla starttider med kvart utom tentamen! Kurstid: 24 mar – 7 juni Kurschef: Niklas Vareman Lärare: CW Christine Wamsler HT Henrik Tehler HH Henrik Hassel US Ullrika Sahlin DP Dmytro Perepolkin NV Niklas Vareman AO Adelina Osmani LS Linn Svegrup JJ Jonas Johansson JMP Jurate Miliute-Plepiene AP Andrius Plepys Salar: Mossen, Ekolog
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven18_vt_20_version2rev2.pdf - 2026-07-10
Prel.Schema MVEN018 - Klimatstrategiska metoder Vårterminen 2020 OBS Alla starttider med kvart utom tentamen! Kurstid: 24 mar – 7 jun, 2020 Kurschef: Niklas Vareman Lärare: CW Christine Wamsler HT Henrik Tehler HH Henrik Hassel US Ullrika Sahlin DP Dmytro Perepolkin NV Niklas Vareman AO Adelina Osmani LS Linn Svegrup JJ Jonas Johansson JMP Jurate Miliute-Plepiene AP Andrius Plepys Salar: Mossen Ös
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven18_vt_20_version3x.pdf - 2026-07-10
