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We challenge the question of how environmental (diet, physical activity, alcohol) factors modify genetic associations put forward by us and others, in recent genome wide association studies (GWAS) of lipoprotein traits, cardiovascular disease (CVD) and obesity and aim to utilize this information in intervention studies and in development of prediction models. We work to further improve genetic C
Our main focus is understanding peripheral pathology in HD and investigate its importance for disease pathogenesis and biomarkers. Our work is based on the hypothesis that insights into peripheral pathology in HD will improve knowledge of key pathogenic mechanisms, possibly providing new biomarkers and novel therapeutic targets.
Minimalinvasiv hjärtkirurgi definieras som hjärtkirurgiska operationstekniker där man avstår från en full median sternotomin (längsgående delning av hela bröstbenet). Hjärtoperationen sker då istället med alternativa exponeringstekniker under det att man använder konventionell hjärt-lungmaskin. Beroende på diagnos utförs antingen operationen med video-assisterad, eller robot-assisterad, endoskopi Minimally invasive cardiac surgery is defined a cardiac surgery with heart-lung machine, but without full median sternotomy. Depending on the underlying disease the surgical procedures can be performed through a 4-6 cm mini-thoracotomy on the right side with either video-assisted or robotic-asssited endoscopy or through a partial split of the sternum. We believe that minimally invasive facilitate
Forskargruppen "Barninfektioner och global barn- och ungdomshälsa" främjar forskning och utbildning. Det primära forskningsområdet är pediatrik och mer specifika inom området barninfektioner, Kawasakis sjukdom, global barn och -ungdomshälsa samt migration. Forskargruppen samarbetar med andra forskargrupper både nationellt och internationellt. Forskargruppen är involverad i utbildningen av läkarsPediatric infectious diseases and global child health is a research group promoting high quality research and education. The primary area of research is Pediatrics and more specific in the field of infectious diseases, Kawasaki disease, global child health and migration. The research group collaborates with research teams both nationally and internationally as well as being involved in the educa
Preeklampsi är ett allvarligt graviditetsrelaterat tillstånd som årligen drabbar 10 miljoner kvinnor världen över. Etiologin är ännu okänd och diagnosen ställs baserad på moderns kliniska symptom: högt blodtryck och någon organpåverkan som debuterar efter 20 veckors graviditet. För närvarande är förlossning den enda ”boten”. Preeklampsi medför en ökad långsiktig risk för utveckling av hjärt-kärlsjPreeclampsia is a severe pregnancy-related condition that annually affects 10M women worldwide. The etiology is largely unknown and diagnosis is currently based on maternal clinical symptoms: high blood pressure and organ damage manifesting after 20 weeks of gestation. Delivery is currently the only cure. Increased long-term risk for cardiovascular diseases and stroke after preeclampsia point to i
Introduction: Human papillomavirus (HPV) infection is an objective marker with a high sensitivity for finding cervical dysplasia. The objective of the current study is to investigate whether HPV testing, combined with liquid-based cytology, is reliable as a test of cure after the loop electrical excision procedure (LEEP). Material and methods: The LEEP was performed in 330 women for excision of ce
Title: Is the Honeymoon Over For Instagram? - A qualitative study on how Generation Y reasons about brand marketing strategies Purpose: The purpose of this thesis is to investigate how Instagram-users from Generation Y reason about various forms of marketing on Instagram, in order to contribute with a deeper understanding on how they view brand strategies to reach them as consumers. Theoretical
The purpose of this thesis is to gain an understanding of the credibility gap between consumers and marketing strategies that aims at gaining moral legitimacy by taking a stand, since it is becoming increasingly important for companies to gain moral legitimacy. By triangulating theories within consumer culture theory, corporate social responsibility and organizational legitimacy and conducting a q
Vår multidisciplinära forskning fokuserar på personer med neurodegenerativa sjukdomar (såsom Parkinsons sjukdom och kognitiva sjukdomar), inklusive personer som har en ökad risk att utveckla sådana sjukdomar. En tidig upptäckt möjliggör tidigt stöd och rehabilitering. Vår forskning identifierar tidiga tecken, konsekvenser, prognostiska faktorer och behov av åtgärder. Forskningen avser även att ökOur multidisciplinary research focus on people with neurodegenerative diseases (ND), such as Parkinson’s disease and major neurocognitive disorders (dementia). We also include people at risk of developing ND. Early detection facilitates timely support and rehabilitation. Our research aims to determine early signs, consequences, unmet needs, and prognostic factors. We also aim to gain an increased
I världen lider flera 100 miljoner människor av autoimmuna sjukdomar och de är ett folkhälsoproblem i paritet med cancer och hjärt/kärlsjukdomar. Vi har fokuserat vår forskning kring en grupp ovanliga men allvarliga autoimmuna sjukdomar, ANCA associerade vaskuliter. Sjukdomarna orsakar en akut inflammation i de små blodkärlen, vilket leder till en snabbt förlöpande glomerulonefrit och livshotande Autoimmune diseases affect several 100 million people world wide and is a tremendous public health problem comparable with heart disease and cancer. We have focused our research to a group of severe autoimmune diseases, called ANCA (anti-neutrophil cytoplasmic antibody) associated systemic vasculitis. The diseases present with acute inflammation in the small vessels and cause rapidly progressive r
The field of research is to uncover the genetic and environmental etiology of autoimmune (type 1) diabetes, celiac disease as well as narcolepsy. The genetics of the disease is dissected also in the spontaneously diabetic BB rat. Specific autoantibody markers are used to predict the clinical onset of diabetes or celiac disease. Longitudinal studies of children at increased risk allow studies of t
Regeringen beslutade 2009 om en satsning på strategiska forskningsområden, som ett led i att skapa världsledande forskning, på rekommendation av Vetenskapsrådet, Fas, Formas, Vinnova och Energimyndigheten.
Lunds universitet har 11 strategiska forskningsområden, vars verksamhet spänner över i princip alla fakulteter och ofta är tvärvetenskaplig, för vilka LU årligen erhåller ca 190 MSEK i In 2009, the government decided to invest in strategic research areas, as part of creating world-leading research, on the recommendation of the Swedish Research Council, Fas, Formas, Vinnova and the Swedish Energy Agency..
Lund University has 11 strategic research areas, the activities of which span virtually all faculties and are often interdisciplinary, for which LU annually receives ab
Sweden's ATMP ecosystem is rapidly expanding, solidifying its place as a key player in Europe. Currently ranking among the top three countries among the EU9 for identified therapeutic ATMP companies, Sweden's strategic investments are further reinforcing its leadership (MSC 2020). This includes ongoing initiatives to establish industrial-scale ATMP manufacturing capabilities, enhancing the country
