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BACKGROUND: Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality o
Objective: To determine the association between radiographic osteoarthritis (OA) and pre-operative function in patients undergoing primary knee replacement. Methods: Single centre study examining pre-operative outcomes in a consecutive series of 525 patients who underwent primary knee replacement for OA between January 2006 and December 2007. Pre-operative data included: demographics, American Soc
An updated search is performed for gluino, top squark, or bottom squark R-hadrons that have come to rest within the ATLAS calorimeter, and decay at some later time to hadronic jets and a neutralino, using 5.0 and 22.9 fb(-1) of pp collisions at 7 and 8 TeV, respectively. Candidate decay events are triggered in selected empty bunch crossings of the LHC in order to remove pp collision backgrounds. S
The purpose of this study is to present a new and improved method for translating the electrocardiographic changes of acute myocardial ischemia into a display which reflects the location and extent of the ischemic area and the associated culprit coronary artery. This method could be automated to present a graphic image of the ischemic area in a manner understandable by all levels of caregivers; fr
This Letter presents the first study of W^{±}W^{±}jj, same-electric-charge diboson production in association with two jets, using 20.3 fb^{-1} of proton-proton collision data at sqrt[s]=8 TeV recorded by the ATLAS detector at the Large Hadron Collider. Events with two reconstructed same-charge leptons (e^{±}e^{±}, e^{±}μ^{±}, and μ^{±}μ^{±}) and two or more jets are analyzed. Production cross sect
Designing a system for computer aided diagnosis is a complex procedure requiring an understanding of the biology of the disease, insight into hospital workflow and awareness of available technical solutions. This paper aims to show that a valuable system can be designed for diagnosing kidney lesions in children and adolescents from 99m Tc-DMSA scintigraphy images. We present the chain of analysis
The correlation between real-world clinical decisions and adherence to published treatment algorithms for problem bleeding episodes in patients with severe hemophilia and inhibitors and the resultant impact on clinical outcomes were assessed. Nine cases documenting treatment for problem bleeding episodes in patients with severe hemophilia and inhibitors were retrospectively reviewed. Adherence to
The anticoagulant vitamin K-dependent protein S (PS) circulates in plasma in two forms, 30% free and 70% being bound to the complement regulatory protein C4b-binding protein (C4BP). The major C4BP isoform consists of 7 alpha-chains and 1 beta-chain (C4BP beta(+)), the chains being linked by disulfide bridges. PS binds to the beta-chain with high affinity. In plasma, PS is in molar excess over C4BP
Vertebral fractures are often painful and lead to reduced quality of life and disability. We compared the efficacy and safety of balloon kyphoplasty to nonsurgical therapy over 24 months in patients with acute painful fractures. Adults with one to three vertebral fractures were randomized within 3 months from onset of pain to undergo kyphoplasty (n = 149) or nonsurgical therapy (n = 151). Quality
The aim of this paper is to make it credible that there are feminist reasons for being a republican about freedom. In focus is Quentin Skinner’s conception of republican, or “neo-Roman”, freedom. Republican theory in history has not excelled in making poverty, gender hierarchy, and racism within the republic into main sources of concern. So can there be a radical republican theory of liberty fit f
Hyperthermia is a frequent complication in patients with acute ischemic stroke. On the other hand, therapeutically induced hypothermia has shown promising potential in animal models of focal cerebral ischemia. This Guideline Document presents the European Stroke Organisation guidelines for the management of temperature in patients with acute ischemic stroke.
CONTEXT: Prior research suggests that drug abuse (DA) is strongly influenced by both genetic and familial environmental factors. No large-scale adoption study has previously attempted to verify and integrate these findings. OBJECTIVE: To determine how genetic and environmental factors contribute to the risk for DA. DESIGN: Follow-up in 9 public databases (1961-2009) of adopted children and their
The use of a label for locally produced products is seen as a good way of promoting these products in Söderslätt and, thereby, promoting regional development. The only common meaning of the concept ?local? is the reference to a geographical area, even though the size of the area differs. Local products are associated with characteristics such as environment, ethics, health, quality and support of
This master thesis presents a qualitative model for performing a due diligence analysis of non- financial risks and their management, the DANFiRM model. The model includes a thinking process and a working procedure for identifying and evaluating the current non-financial risk exposure at the target enterprise and further required measures for altering risk exposure and risk management activities t
Metals play a key role as a cornerstone of our modern society; they are part of the most basic elements of our daily life and have been part of our lifestyles for millennia. Current trends of metal production point out that developing countries in order to attain a developed-countries consumption level will require 3-9 times the present metal stock per capita, yet their mining practices are far fr
Countries around the world are employing renewable energy policies to increase renewable electricity in their electricity mix. Trinidad and Tobago (T&T), located in the Caribbean, has endogenous sources of oil and natural gas and has not yet capitalised on sources of renewable energy. The country‟s electricity is currently dominantly generated from natural gas however the natural gas reserves
Det här examensarbetet ger en översikt över organiskt material (kerogen) i Jordens yngre lagrade berggrund och hur detta material omvandlats till olja och naturgas genom olika geologiska processer. De viktigaste är tryck, temperatur och tid. Med fortskridande sedimentpålagring förs det organiskt rika sedimenten successivt ned på större djup, där de genomgår en så kallad mognadsprocess till följd aThe origin, composition and maturity of kerogen, and its conversion to petroleum is reviewed. Various methods for estimating the maximum temperature to which kerogen and potential source rocks were subjected are also reviewed. Several kerogen maturation parameters can be distinguished and grouped into two categories: chemical paleothermometres and biological paleothermometres. Biological paleother
Decision analysis is often used to help decision makers choose among alternatives, based on the expected utility associated to each alternative as function of its consequences and potential impacts. Environmental impacts are not always among the prioritized concerns of traditional decision making. This has fostered the development of several environmental problems and is nowadays a reason of conce
