Filetype
Inhaled therapies are central to the treatment of asthma and chronic obstructive pulmonary disease. Physicians consider many factors when selecting the most appropriate inhaler device, including device efficacy and the cost to the health care system. This review aims to discuss the factors that are important when considering inhaler devices and the importance of continuity in the choice of inhaler
A thorough computational study has been performed to investigate oxygen atom transfer (OAT) reactions catalyzed by dimethyl sulfoxide reductase (DMSOR) with a catalytic molybdenum or tungsten ion. Thirteen different density functional theory (DFT) methods have been employed to obtain structural parameters along the reaction pathway, and single-point energies were computed with local correlation co
The antiphospholipid syndrome is defined by the presence of antiphospholipid antibodies in blood of patients with thrombosis or fetal loss. There is ample evidence that beta(2)-glycoprotein I (beta(2)GPI) is the major antigen for antiphospholipid antibodies. The autoantibodies recognize beta(2)GPI when bound to anionic surfaces and not in solution. We showed that beta(2)GPI can exist in at least 2
Aims: The purpose of this study was to investigate criterion-related validity and test–retest repeatability of the heart rate monitor Polar RS400 versus electrocardiogram (ECG). Methodology: Ten healthy subjects, 19–34 years, performed a cycle ergometer test 5 min on each load (50, 100 and 150 W). Heart rate (HR) was measured with ECG and Polar RS400 and recorded digitally. After at least one hour
Arctic sea ice represents an important component of the climate system, and the present reduction of sea ice in the Arctic is of major concern. Despite its importance, little is known about past changes in sea-ice cover and the underlying forcing mechanisms. Here, we use diatom assemblages from a marine sediment core collected from the West Greenland shelf to reconstruct changes in sea-ice cover o
This Letter presents a search for tb resonances in 1.04 fb(-1) of LHC proton-proton collision data collected by the ATLAS detector at a center-of-mass energy of 7 TeV. Events with a lepton, missing transverse momentum, and two jets are selected and the invariant mass of the corresponding final state is reconstructed. The search exploits the shape of the tb invariant mass distribution compared to t
Using a direct imaging method, we experimentally investigate the reversal of magnetic islands in a bit-patterned media sample based on a pre-patterned substrate. Due to systematic variation of the island distances in the media, we are able to study the influence of the dipolar interaction on the switching-field distribution of the island ensemble. The experimental findings are explained by an anal
Biological diversity encompasses the genetic diversity within each species, the range of species in a given ecosystem e.g. species diversity and the diversity of ecosystems across an entire region (Primack, 2000). At present 1 per cent of the world’s described species are threatened with extinction. The most pervasive and overriding threat is habitat loss and degradation due to human activity such
What kind of indispensable cognitive ability is needed for intelligence, sociability, communication, and technology to emerge on a habitable planet? My answer is simple: intersubjectivity. I stress the significance of intersubjectivity, of shared cognition, for extraterrestrial intelligence and interstellar communication, and argue that it is in fact crucial and indispensable for any successful in
This thesis is divided into two parts in which two different aspects of the Large Hadron Collider (LHC) Project are discussed. The first part describes the design of a transition radiation tracker (TRT) for the inner detector in ATLAS. In particular, the barrel part was studied in detail. The barrel TRT consists of 52 544 1.5-m-long proportional tubes (straws), parallel to the beam axis and each
Proton exchange membrane fuel cell (PEMFC) systems have been investigated as alternative power sources for the stationary and automotive applications. However, they do not appear on the market yet. One of the main reasons is the difficulty of the water/thermal management in the system. Several water recovery schemes have been proposed to overcome this difficulty and to simplify the system configur
With a worldwide increase in disasters, the effects of climate change are already being felt, and it is the urban poor in developing countries that are most at risk. There is an urgent need to better understand the factors that determine people’s capacity to cope with and adapt to adverse climate conditions. This paper examines the influence of formal education in determining the adaptive capacity
Popular Abstract in Swedish Basala ganglierna ligger under hjärnbarken i hjärnan och består av grupper av nervceller som är förbundna med varandra och med hjärnbarken. Till dessa grupper av nervceller hör striatum, globus pallidus, subthalamicus-kärnan och substantia nigra. Patologiska förändringar i olika delar av basala ganglierna orsakar många av de symptom som kännetecknar Huntington's och ParHuntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. calcium-dependent cell death induced by activation of NMDA receptors, has been hypothesized to play an important role in HD. Ou
It is shown that under certain regularity conditions on the norm, the functions in a nontrivial invariant subspace of the backward shift operator have meromorphic pseudocontinuations in the Nevanlinna class of the exterior of the unit disk. In addition, we provide a regularity condition which implies that the subspace itself is contained in the Nevanlinna class of the disc.
Popular Abstract in Swedish Magnetresonanstomografi (MRT) är en metod för framställning av bilder av kroppen och av sjukliga förändringar i kroppen. När metoden introducerades ansågs den utomordentligt goda inbyggda vävnadskontrasten vara tillräcklig för att särskilja olika sjukliga förändringar, speciellt i hjärnan. Det har emellertid visat sig att förmågan att upptäcka sjukliga förändringar är oAims of the study The aims of this study using Gadodiamide injection were to investigate: · Whether Gadodiamide injection was comparable to Gd-DTPA for the enhancement of CNS lesions. · The contrast effect at different field strengths. · The effective time-window for the enhancement of blood-brain barrier damage. · The relations between the concentration of contrast agent and enhancement in p
