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Although biologics have revolutionized psoriasis treatment, they pose a significant burden on the healthcare budget. With the wide range of biologics available and the increasing number of biosimilars, insights into the real-world cost per responder (CPR) are required. Therefore, this study aims to evaluate the real-world CPR of adalimumab, ustekinumab, IL17-and IL23-inhibitors, incorporating both

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Analyzing kinetic experiments on protein aggregation using integrated rate laws has led to numerous advances in our understanding of the fundamental chemical mechanisms behind amyloidogenic disorders such as Alzheimer's and Parkinson's diseases. However, the description of biologically relevant processes may require rate equations that are too complex to solve using existing methods, hindering mec

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This thesis investigates the volatility structures found in forward-looking fundamental valuations of the Swedish stock index OMXS30. The evaluated data constitutes daily observations of P/E ratios based on twelve months earnings estimates during the period 2009-01-02 until 2018-10-18. The analysis is conducted by applying a GARCH modelling framework to a log-return transformed return series deriv

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The aim of this empirical study was to find out which characteristics, behaviors, and drives high-performing women have in common in order to illuminate why they have become successful in their work. The aim also included getting insights into some of the challenges that these women meet. Participants were fifteen high-performing women who work in business and academia in Sweden. Semi-structured,

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Sub Saharan African (SSA) countries are facing severe economic challenges such as high trade costs, poor trade performance and low growth levels. As a result development assistance is needed to overcome these difficulties. SSA countries receive the highest share of Aid for Trade (AfT) and therefore it is important to assess the effects of AfT. This study investigates the trade effect of AfT on tra

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A method is presented for the determination of complex-valued compression and shear elastic moduli of polymers for ultrasound applications. The resulting values, which are scarcely reported in the literature, are found with uncertainties typically around 1% (real part) and 6% (imaginary part). The method involves a setup consisting of a cm-radius, mm-thick polymer ring glued concentrically to a di

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This paper analyzes if patients’ demand for Direct-to-Consumer Telemedicine (DCT) providers is affected by a change in patient fees. The paper utilizes a natural experiment when the patient fee increased for patients in Region Stockholm using one DCT provider but remained unchanged for other DCT providers. By using DCT visits per month for all other regions as control, the effect on the demand for

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The combined global emergence of a sustainable development discourse and Swedish policies requiring municipalities to rapidly build new housing have led Lund to develop Brunnshög. This pioneering megaproject balances urban expansion with high sustainability ambitions. Through the lens of urban political ecology, this thesis aims at analysing Brunnshög’s dominant sustainability narrative as told by

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The ability to hear is essential for receiving auditory signals, which serve as warnings and alerts in many situations, including fire evacuation. However, people with hearing impairments may miss out such signals and can be exposed to dangerous situations. This is particularly relevant in scenarios where audible alarms are the primary form of alert, such as in fire scenarios, natural hazards, or

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ADHD is a common neurodevelopmental disorder that is defined by a pattern of hyperactivity and/or inattention that negatively affects an individual’s ability to function in everyday life. There are a multitude of challenges in correctly diagnosing ADHD. Symptoms are primarily behavior based and there are not any good biomarkers that can be used to help clinicians to diagnose the disorder correctly

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This thesis is inspired by the lack of academic discourse on human rights aspects of human space settlement. It builds on the ever-growing literature on colonizing Mars and the ongoing public debate on the benefits versus disadvantages thereof. Taking on a critical approach, this thesis opens up a conversation on power, universalism, and legitimacy within space exploration, questioning both the on

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A prototype of a novel 10B-based neutron detector called the Multi-Grid detector has been constructed, tested and commissioned for the European Spallation Source (ESS). The detector is constructed after the specifications set by the CSPEC instrument at ESS and is therefore called the CSPEC Multi-Grid detector. The detector uses multiple layers of solid coating containing 10B4C on the edges of a vo

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The median age for Swedish earth embankment dams is about 60 years. Due to its longevity, one of the major concerns is the internal erosion causing increased seepage through the dam, which ultimately may increases the risk for dam failure. To meet this challenge, there is a need for improved monitoring methods. This in turn requires sensors to be installed inside the earth embankment dams in order

Sgel49 schedule vt2018

SGEL49 Spring semester 2018 Sustainable development from a Global, Regional and Local perspective Day Time Content Teacher Room WEEK ONE- Basics Thursday 15 February 13-15 Introduction meeting & Lecture 1: An over-view: the rise of Sustainable Development (Scoones, 2016, Faran, 2010) CB 111 Friday 16 February 9-11 Seminar 1: The road to SD- Individual behavior, the economy and Sustainable Developm

https://www.keg.lu.se/sites/keg.lu.se/files/sgel49_schedule_vt2018.pdf - 2026-07-12

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Almost 30 years have passed since the dismantling of South Africa’s apartheid system, putting an end to the long history of racial segregation, discrimination, and oppression. But has it really changed? This research highlights the emergence of Black Economic Empowerment (BEE) as an affirmative policy instrument to advance land reform and rectify the enduring inequalities in the country’s agricult

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The geology of Vombsänkan is characterized by a complex sequence of Quaternary deposits overlying the Paleozoic sedimentary bedrock. The area is 759 km2 and has recorded several ice advances followed by glacial retreats and ice melting. The glacial history of Vombsänkan, which is controlled by sequential geological events such as active ice-margin and stagnant ice, formation of dead ice as well as

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With aging populations, unequal access to care, and shortages of staff, healthcare systems today are facing many challenges. Technology advancements, with artificial intelligence (AI) in particular, have been one of the main drivers of innovation in multiple industries. Although the healthcare sector is moving slower compared to other industries, there is great potential for relieving healthcare w