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Collimated sprays of paticle, known as jets,are abundantly produced in high-energy proton-proton (pp) collisions, and are predicted by many theories of physics beyond the Standard Model. This thesis reports first on the calibration of jets with focus on the data-driven in situ calibration. Two searches for new physics phenomena in events with jets in the final state are then presented. The analyse
Prior to the COVID-19 crisis, global air transport demand was expected to triple between 2020 and 2050. The pandemic, which reduced global air travel significantly, provides an opportunity to discuss the scale, distribution and growth of aviation until 2018, also with a view to consider the climate change implications of a return to volume growth. Industry statistics, data provided by supranationa
INTRODUCTION: Infant iron status assessments may be difficult to interpret due to infections. The soluble transferrin receptor (sTfR) has been suggested as a biomarker mainly unaffected by the acute phase response. Reference intervals reflecting dynamics of infant growth first year in life are not well established.METHODS: The sTfR and CRP concentrations were measured in samples from 451 term infa
As a result of the energy performance of the buildings directive (EPBD 2010), the requirements have been gradually tightened in the Swedish building regulations. For the purpose of the directive to be realized, it is becoming increasingly important to ensure that buildings actually live up to the minimum rules laid down in the Swedish Building Regulations (BBR) or more ambitious requirements impos
This study focuses on the boundary-spanning nature of sustainable business model innovation, studying multi-stakeholder engagement and alignment. Drawing on the concept of boundary work, we explore the different types of organizational boundary changes between focal companies and their external stakeholders, investigating specifically the process of exploring, negotiating, disrupting and realignin
BACKGROUND: F8 int1h inversions (Inv1) are detected in 1-2% of severe hemophilia A (HA) patients. Long-range polymerase chain reaction (PCR) and inverse-shifting PCR have been used to diagnose these inversions.OBJECTIVES: To design and validate a sensitive and robust assay for detection of F8 Inv1 inversions.METHODS: Archival DNA samples were investigated using mile-post assays and droplet digital
Background: Global transcriptional profiling of individual cells represents a powerful approach to systematically survey contributions from cell-specific molecular phenotypes to human disease states but requires tissue-specific protocols. Here we sought to comprehensively evaluate protocols for single cell isolation and transcriptional profiling from heart tissue, focusing particularly on frozen t
The RNA integrity number (RIN) is a frequently used quality metric to assess the completeness of rRNA, as a proxy for the corresponding mRNA in a tissue. Current methods operate at bulk resolution and provide a single average estimate for the whole sample. Spatial transcriptomics technologies have emerged and shown their value by placing gene expression into a tissue context, resulting in transcri
As for the automotive industry, industry and academia are making extensive efforts to create autonomous ships. The solutions for this are very technology-intense. Many building blocks, often relying on AI technology, need to work together to create a complete system that is safe and reliable to use. Even when the ships are fully unmanned, humans are still foreseen to guide the ships when unknown s
BACKGROUND: Preterm infants are susceptible to hyperglycemia and hypoglycemia, conditions which may lead to adverse neurodevelopment. The use of continuous glucose monitoring devices (CGM) might help keeping glucose levels in the normal range, and reduce the need for blood sampling. However, the use of CGM might be associated with harms in the preterm infant. OBJECTIVES: Objective one: to assess t
A 24-hour bioblitz was performed by employees in the immediate surroundings of the Biological Institute in the city of Lund, South Sweden, on the 15th of June 2018. It produced 928 taxa, 411 of which were insects. Six species of Hymenoptera Parasitica were new to Sweden: Tumidiclava bimaculata (Blood), Lathromeris germanica (Girault), Aprostocetus crassiceps Graham, Quadrastichus anysis (Walker), Insect finds during the bioblitz of the Department of Biology in Lund in June 2018A 24-hour bioblitz was performed by employees in the immediate surroundings of the Biological Institute in the city of Lund, South Sweden, on the 15th of June 2018. It produced 928 taxa, 411 of which were insects. Six species of Hymenoptera Parasitica were new to Sweden: Tumidiclava bimaculata (Blood), Lathromeris ge
BACKGROUND AND PURPOSE: Radiotherapy treatment planning algorithms continue to develop and current planning systems typically offer simpler, but faster, algorithms, which may be 2, 2.5 or 3D in modelling scatter, but which do not model electron transport (type a) and more accurate algorithms which aim to be fully 3D, i.e. which model 3D scatter and also model electron transport (type b). A range o
Parks, remnants of natural habitats and other green areas are important for preserving biodiversity in urban areas. Here, we investigate the relative importance of habitat type and connectivity for butterfly species richness in the city of Malmo, Sweden. Further, we compare species richness and composition in the urban habitats with that in the surrounding agricultural landscape using previously p
Here we examine the efficiency of different immobilized cell gradients applied to immobilized Saccharomyces cerevisiae fermenting glucose to ethanol. We developed a simulation model to fully study the competing effects of mass transfer hindrance and kinetics. It is based on a diffusion-reaction model and can be used to analyze the different cell concentration profiles inside an immobilized gel bea
Identification of ectomycorrhizal (ECM) fungi is often achieved through comparisons of ribosomal DNA internal transcribed spacer (ITS) sequences with accessioned sequences deposited in public databases. A major problem encountered is that annotation of the sequences in these databases is not always complete or trustworthy. In order to overcome this deficiency, we report on UNITE, an open-access da
The quality of the working environment affects the health status of a population. In the absence of government intervention this quality would be determined by market forces, but the market outcome is generally not accepted. Instead public policy attempts to carefully monitor the level of occupational hazards, which are invariably subject to regulation in industrialized countries. However, this st
Stochastic leaky integrate-and-fire (LIF) neuronal models are common theoretical tools for studying properties of real neuronal systems. Experimental data of frequently sampled membrane potential measurements between spikes show that the assumption of constant parameter values is not realistic and that some (random) fluctuations are occurring. In this article, we extend the stochastic LIF model, a
A sensitivity analysis was performed testingweathering rates, critical loads andexceedances for Swedish forest soils using Monte Carlosimulations of the PROFILE model. Different subsetsof input data were investigated with respect to theirpotential to reduce data uncertainty at site level butalso for modified estimates of the 5%-ile critical load andthe 95%-ile exceedance on 150×150 kmresolution. P
Resource sharing in heterogeneous environments has been shown to increase growth and survival of clonal plants. In addition, plants in harsh climates have been suggested to have higher levels of resource sharing than plants in milder climates. We experimentally investigated the level of resource sharing in plants from garden and forest habitats from two regions with contrasting climates. The clona
