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During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles for gene transfer to the adult central nervous system. In recent experiments, in the rat model of Parkinson's disease, all three vector systems have been shown to be effective for long-term delivery of glial cell line-

Reliable estimates of past land cover are critical for assessing potential effects of anthropogenic land-cover changes on past earth surface-climate feedbacks and landscape complexity. Fossil pollen records from lakes and bogs have provided important information on past natural and human-induced vegetation cover. However, those records provide only point estimates of past land cover, and not the s

The exclusive charmonium production process in pp annihilation with an associated π0 meson pp→J/ψπ0 is studied in the framework of QCD collinear factorization. The feasibility of measuring this reaction through the J/ψ→e+e- decay channel with the AntiProton ANnihilation at DArmstadt (PANDA) experiment is investigated. Simulations on signal reconstruction efficiency as well as the background reject

This paper examines the continuity, change and adaptation of blat – as a Soviet time, informal, economic transaction network, that existed as a response to a non-functional economy. The analysis is based on 33 in-depth interviews conducted in 2009 during a pilot field study in Ukraine and Belarus. The main focus is on individuals’ descriptions, justifications and explanations of their ongoing info

The study explores divergent representations and cultural identity in a historically contested landscape. The first form of representations includes politically amended place marketing. It is analysed how public discourse on a city’s development and regeneration articulate inscriptions of local authorities to pursue political-economic agendas. The second form of representations is diaspora’s imagi

Although being promoted as the most eco-friendly form of transportation, the shipping sector currently accounts for around 3 % of global greenhouse gas (GHG) emissions, however, with increasing global trade emissions are expected to increase. Even if energy efficiency gains have been accomplished, the majority of the global fleet continue to run on fossil fuels and the total emissions from ships a

Performance-based, service-life design of wood has been the focus of much research in recent decades. Previous works have been synthesized in various factorized design frameworks presented in the form of technical reports. Factorization does not consider the non-linear dependency between decay-influencing effects, such as between detail design and climate variables. The CLICKdesign project is a jo

Rapid deforestation is a major sustainability challenge, partly as the loss of carbon sinks exacerbates global climate change. In Cambodia, more than 13% of the total land area has been contracted out to foreign and domestic agribusinesses in the form of economic land concessions, causing rapid large-scale land use change and deforestation. Additionally, the distant drivers of local and global env

It is a common experience among children to witness domestic violence, but how much does it affect the child later on in life? The purpose of this paper is to present what happens to the child mentally and physically when domestic violence against women results in the death of a mother and the imprisonment of a father. The paper also presents ways to minimize the impact the event has on the child.

Water for firefighting is often associated with drinking water, due to fire hydrants. Fire hydrants have been installed in towns for a long time and are one of the most common ways for the rescue service to get hold of water for extinguishing fires. This report evaluates the ways that the rescue service uses their water and how the get continuously water to the fire site. Other extinguishing metho

Kina har en fast valutakurs gentemot andra valutor. Från 1980-talet och framåt har man haft en ekonomisk politik med en stark export- och investeringsledd tillväxt. Kina har under senare år haft stora bytesbalansöverskott mot framför allt USA men också mot EU och Japan. Bytesbalansöverskottet har gjort att Kinas valutareserv har ökat kraftigt. USA har kritiserat Kina för att hålla valutan undervä

For many years, questions about the future have been marginalised within the social sciences: asking how we might live in a post-fossil society, or what are the key decisions and events that could take us there, has been seen as outside of the disciplinary scope. In this chapter – which takes as its point of departure the ‘speculative turn’ that is increasingly inspiring a range of works, from for

The countries of the European Union are in an ongoing phase of integration. The influences on individual states domestic structures are unquestionable and the governing prerequisites have changed significantly. Poland, a relatively new member state is in the middle of the process and so this study analyses the effects of Europeanization on polishes domestic structures. The study examines four pub-

Substitution of fossil transport fuels with biodiesel and bioethanol can lower greenhouse gas emissions, reduce dependency on oil and strengthen agriculture. This thesis describes, compares and analyses market penetration of biodiesel and bioethanol, as well as the socio-political context for biofuels, in Germany and the United Kingdom. General conclusions for policy makers wanting to design or ch

As growing populations concentrate in urban areas, it has become apparent that many global problems are a cumulative reflection of unsustainable practices at the local level. Correspondingly, there has been an increasing need to monitor and manage sustainable community growth, which includes a balance of environmental, economic, health, and social measures. Throughout the last decade, the communi