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The blood group ABO gene shows considerable polymorphism in most of the 7 exons. Introns examined so far have also shown blood group-related polymorphisms, as has an upstream enhancer region. Several polymorphisms affect the specificity of the gene product (glycosyltransferase) and explain the occurrence of blood group A and B. Various lethal mutations result in blood group O. Other mutations are

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The Zumaya section, northern Spain, is a suitable candidate to define the Global Stratotype Section and Point for the base of the Selandian Stage (Palaeocene) because of its excellent accessibility, exposure and stratigraphic continuity. Uncertainties exist, however, with regard to the stratigraphic horizon where to place the Danian/Selandian (D/S) boundary. Five potential stratigraphic horizons (

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The paper compares PM10 concentrations in railroad environments with EU air quality standards and characterizes particle concentrations and particle properties in relation to train traffic. The results show that PM10 concentrations in ground-level railroad environments do not exceed the EU directive 24-h limit value, while on the platforms of the two subterranean stations PM10 concentrations were

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This study uses a discontinuity in the Swedish tertiary eligibility requirement to estimate the probability of enrolling in tertiary education, and the payoff thereof. Regression discontinuity results, show that achieving tertiary eligibility in upper-secondary education, increases the probability of enrolling in tertiary education by around 10–15 and 7 percentage points for students who enrolled

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This paper presents a preliminary method developed for improved decision-support based on probabilistic methods for risk assessment using building performance simulations. The aim of the method is to support the decision-maker in all stages of the building process when deciding on the design of a building by including uncertainties and quantifying; the probability of fulfilling objectives; energy

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Downlink beamforming in Massive MIMO either relies on uplink pilot measurements--exploiting reciprocity and time-division duplexing (TDD) operation, or on the use of a predetermined grid of beams with user equipments reporting their preferred beams, mostly in frequency-division duplexing (FDD) operation. Massive MIMO in its originally conceived form uses the first strategy, with uplink pilots, whe

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Current research on enzyme based electrochemical biosensors deals essentially with the same target analytes as was at focus in the early days of biosensor research, that is those within the clinical/medical, food/agriculture, and environmental fields [1•–13]. However, there has been substantial progress through the years and progress continues, as resumed in Figure 1A. One of the major differences

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This Forum addresses oxidative reactions of hemoglobin (Hb) and explores the underlying mechanisms of some of these reactions that contribute to the pathophysiology associated with hemolytic anemia and Hb-based oxygen therapeutics. A special focus of this Forum is on the understanding of naturally occurring mutations in human Hb and how these mutations were influenced overtime by variety of oxidat

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We identified clusters of atypical sensory functioning adults with ASC by hierarchical cluster analysis. A new scale for commonly self-reported sensory reactivity was used as a measure. In a low frequency group (n = 37), all subscale scores were relatively low, in particular atypical sensory/motor reactivity. In the intermediate group (n = 17) hyperreactivity, sensory interests and sensory/motor i

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The production cross-section of a top quark in association with a W boson is measured using proton–proton collisions at s√=8TeV. The dataset corresponds to an integrated luminosity of 20.2fb−1, and was collected in 2012 by the ATLAS detector at the Large Hadron Collider at CERN. The analysis is performed in the single-lepton channel. Events are selected by requiring one isolated lepton (electron o

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This article investigates sustainability in the performance measurement systems of Swedish manufacturing companies. It builds on a previous study that documents relatively few direct environmental indicators at shop floor level, which raises questions about possible indirect links between existing indicators and the environment that could be used to improve the environmental aspect of company's su

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Natural lifetimes of some highly excited levels in the Pb-I spectrum have been measured by the zero field level crossing (Hanle) method. The levels were reached by optical excitation from the metastable 6p2 3P2 and 6p2 3P1 states, were a considerable population had been created by means of adc discharge in a Pb atomic beam. An atomic beam source producing atoms in metastable states is described. F

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The purpose of this work is to present results from an ongoing study on how the presence of surfaces influences the buckling properties of nanowires. This study is performed using molecular statics simulations where the interatomic interaction is modelled using an embedded atom potential (EAM) fitted to gold properties. The considered nanowires have rectangular cross sections with cross sectional

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Maternal use of some drugs, notably paracetamol and drugs for gastroesophageal reflux, has been associated with an increased risk of childhood asthma in the child. We wanted to analyze these associations with consideration to the confounding of maternal asthma.