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BACKGROUND: Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the germinal matrix are likely to play a triggering role. Antithrombin, a glycoprotein synthesized in the liver, is the major plasma inhibi

This volume provides an overview of applications of conceptual spaces theory, beginning with an introduction to the modeling tool that unifies the chapters. The first section explores issues of linguistic semantics, including speakers negotiation of meaning. Further sections address computational and ontological aspects of constructing conceptual spaces, while the final section looks at philosophi

This article applies a neo-documentalist approach to explore disciplinary information and knowledge making practices. The aim is to show how conceptions and materialities of what counts as documentation and documents are intertwined with changing and persisting disciplinary and sub-disciplinary practices of producing information and knowledge, of knowing, and informing. A collective, multivocal au

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess whether heparin treatment (both UFH and LMWH) in preterm and term newborn infants with diagnosed thrombosis reduces the rate of mortality and morbidity. The intervention will be compared to placebo or no treatment. In addition, the safety of heparin therapy (both UFH and LMWH) will be assessed for

Purpose The purpose is to develop a framework for measuring the S&OP process performance. Design/methodology/approach The method used is a multiple case study of five companies from different industries based on data from twelve structured interviews. Findings The main result is a framework to measure the S&OP process. It includes concrete suggestions for organizations when developing me

The laminar burning velocity is a fundamental property of combustiblemixtures important for kinetic model validation as well as for practicalapplications. Many efforts are directed towards its accurate determination.The heat flux method is one of the commonly recognized methodsfor measuring laminar burning velocity, however, the information on theaccuracy of the method is scattered in the literatu

Eukaryotic genomes, particularly animal genomes, have a complex, nonuniform, and nonrandom internal compositional organization. The compositional organization of animal genomes can be described as a mosaic of discrete genomic regions, called "compositional domains," each with a distinct GC content that significantly differs from those of its upstream and downstream neighboring domains. A typical a

The formation of cold gas giants similar to Jupiter and Saturn in orbit and mass is a great challenge for planetesimal-driven core accretion models because the core growth rates far from the star are low. Here we model the growth and migration of single protoplanets that accrete planetesimals and gas. We integrated the core growth rate using fits in the literature to N-body simulations, which prov

Huntington's disease (HD) is a fatal genetic neurodegenerative disorder. It has mainly been considered a movement disorder with cognitive symptoms and these features have been associated with pathology of the striatum and cerebral cortex. Importantly, individuals with the mutant huntingtin gene suffer from a spectrum of non-motor features often decades before the motor disorder manifests. These sy

Ultrashort laser pulses have become an indispensable tool in physics, chemistry and engineering. Their numerous applications call for accurate and robust characterization techniques able to reliably retrieve the pulse's intensity profile. Different methods, such as FROG [1] or SPIDER [2] and their variants, have been developed in past decades and are now common in many laboratories. More novel app

Measurements achieved with ptychographic imaging are a special case of diffraction measurements. They are generated by illuminating small parts of a sample with, e.g., a focused X-ray beam. By shifting the sample, a set of far-field diffraction patterns of the whole sample is then obtained. From a mathematical point of view those measurements are the squared modulus of the windowed Fourier transfo

Background: In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach. Methods: Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefine

This study presents the main features of the Swedish approach for resolving the banking crisis of 1991-93 by condensing them into seven policy lessons. These concern (1) the importance of political unity behind the resolution policy, (2) a government blanket guarantee of the financial obligations of the banking system, (3) swift policy action where acting early was more important than acting in e

Several experiments were conducted at the 10 MV Van-de-Graaff tandem accelerator at the Institute of Nuclear Physics, Cologne, to detect proton emission from the isomeric 6457-keV 10+ state in 54Ni. Excitation functions for two fusion–evaporation reactions were measured to maximise the population of the rare two-neutron evaporation channel from a 56Ni compound nucleus. The search for delayed proto

Over the past decade, the prevailing view for the molecular and cellular pathogenesis of Alzheimer's disease (AD) has centred on the β-amyloid (Aβ) peptide that accumulates in vulnerable brain areas in the disease. The amyloid cascade hypothesis postulates that the build up of Aβ in the brain causes damage to neurons, leading to dysfunction and loss of neurons, and the clinical phenotype of the am