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We propose simple estimation of the location parameter for a density that is unbounded at the mode. The estimator maximizes a modified likelihood in which the singular term in the full likelihood is left out, whenever the parameter value approaches a neighborhood of the singularity location. The consistency and super-efficiency of this maximum leave-one-out likelihood estimator is shown through a
Many children with adverse reactions to beta-lactams are labelled as allergic without performing an allergy study to confirm it. In this retrospective study of 10 years, we have detected only 3.3% positive cases. Although International Guidelines recommend a second allergy work-up in patients with a negative study, we found from our results a low profitability of retesting.
Introduction Musculoskeletal disorders (MSD) are nowadays seen within a biopsychosocial framework, including salutogenic factors, motivation factors, and coping ability. Such a framework recognizes the importance of motivational factors in health promotion and in rehabilitation. The Motivation for Change Questionnaire (MCQ) has been developed to measure the strength of individuals' motivation for
Parkinson´s disease (PD) is a neurodegenerative disorder characterized by the typical motor symptoms, akinesia/bradykinesia, rigidity and resting tremor. These symptoms are caused by a deficiency of dopamine (DA) in the brain, which depends on degeneration of DA neurons in the substantia nigra. The most effective treatment for PD is the DA precursor, L-DOPA. Unfortunately, within a few years, L-DO
The Naqshbandi-Haqqani Sufi order has spread throughout the world extensively since it was founded in 1973 by its Sheikh Muhammad Nazim Adil al-Haqqani. The present thesis analyses one local branch of that order in Eastern London within a theoretical framework of New Social Movements, as formulated by the Italian sociologist Alberto Melucci. A general picture of Muslim presence in Britain is given
The aim of this thesis is to identify the key factors that affect the biomass potential for energy purposes in the EU-15 in the short term (2010) and in the long term (2050) and to examine the extent to which these factors are taken into consideration in recent European biomass potential studies. In the short term, the production and use of energy carriers based on renewable energy sources (RES) n
Patent pools are contractual agreements where patent rights are transferred to a common holding company for the purpose of jointly licensing of patent portfolios. They have posed and still constitute one of the major challenges to competition policy. The arrangements have the ability to integrate complementary technology, reduce transaction costs and avoid infringement. At the same time, they cons
During the past two decades several studies pointed out the contradiction between abundance of natural resources and its negative impact on economic growth and development. This paradox has been widely observed and documented throughout the development literature. In this context, China’s increasing demand for natural resources and consequent growing trade and influence in developing countries has
During the past years Enterprise 2.0 has become widely spread among organization. However is there not enough awareness in the organizations concerning the necessary organizational changes which companies need to address when planning for the shift to Enterprise 2.0. In this study we aim to indentify solutions for success which affect if an Enterprise 2.0 implementation will succeed or not and how
Purpose: To investigate how consumers understand free services on the Internet. Theories: The research is primarily based upon theories of gift giving. Methodology and analysis: The Internet is not a tangible marketplace and in order to understand the value of the free services online, we used consumers' behavioral accounts to explain how they perceive the free services that are common online.
Beskattning av pokervinster har inte minst under 2011 varit ett ämne för många diskussioner i media. Vissa anser att det krävs stora inslag av skicklighet för att vara duktig på poker och att det inte borde anses vara ett lotteri. Denna skicklighetsaspekt var fall för prövning i HD under 2011 i den s.k. Grebbestadsdomen. Vissa ansåg att domen skulle direkt avgöra om pokervinster skulle komma att bTaxation on poker winnings have not the least in 2011 been a topic of discussion in the media. Some believe that it requires significant element of skill to be good at poker and that it should not be considered a lottery. This skill aspect was tried in the Supreme Court in 2011 in the so-called Grebbestad verdict. Some felt that the appeal would directly determine whether poker profits would be ta
This thesis visits the forefront of algorithmic research on edge coloring of cubic graphs. We select a set of algorithms that are among the asymptotically fastest known today. Each algorithm has exponential time complexity, owing to the NP-completeness of edge coloring, but their space complexities differ greatly. They are implemented in a popular high-level programming language to compare their p
This thesis presents and tests the convergence rate of the Dirichlet-Neumann algorithm for two Poisson equations coupled by transmission boundary conditions. Three second order discretisation methods are used when analyzing the convergence: standard equidistant finite difference, standard adaptive linear finite element, and standard adaptive finite volume discretisation of Poisson's equation.
This thesis explores the possibility for (re)defining the relationship between humans and robots with conversational interfaces. It does so by looking at the creation process of a voice and text-based virtual assistant for tourists from the perspective of critical posthumanism and posthuman performativity. In a reflexive fashion, I analyze my involvement in a tech start-up, in order to argue that,
Anthropogenic land-use covers a constantly increasing fraction of the terrestrial surface area. By employing a dynamic global vegetation model, human-induced changes in the terrestrial water balance as compared to an undisturbed scenario were simulated. The results suggest that humanity is a main driver of change in the terrestrial water balance in general and green water in particular. Most strik
