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Clinical research usually involves time-to-event survival analysis, in which the presence of a competing event is prevalent. It is acceptable to use the conventional Cox proportional hazard regression to model cause-specific hazard. However, this cause-specific hazard cannot directly translate to the cumulative incidence function, and the latter is usually clinically relevant. The subdistribution
Mobile Stroke Units (MSUs) are specialized ambulances that can diagnose and treat stroke patients; hence, reducing the time to treatment for stroke patients. Optimal placement of MSUs in a geographic region enables to maximize access to treatment for stroke patients. We contribute a mathematical model to optimally place MSUs in a geographic region. The objective function of the model takes the tra
In this paper we inquire into the relationships between the Greek myth of Phaeton and Volkswagen's project to produce a luxury car (named Phaeton). Volkswagen apparently felt that the lack of a luxury car opened the possibility to question their 'son-of-God status', just like Phaeton in the Greek story. This inquiry is contextualized in the emergence of a more and more direct art-management relati
Increasing nutrient concentrations (eutrophication) and water color due to dissolved organic matter (brownification) pose continuous threats to freshwater ecosystems worldwide, threatening ecosystem services like drinking water supply. Changing the increasing trends of eutrophication and brownification on our aquatic ecosystems is challenging. However, constructed wetlands could be a potential loc
The evolution of reading frame maintenance must have been an early event, and presumably preceded the emergence of the three domains Archaea, Bacteria and Eukarya. Features evolved early in reading frame maintenance may still exist in present-day organisms. We show that one such feature may be the modified nucleoside 1-methylguanosine (m(1)G37), which prevents frameshifting and is present adjacent
Alzheimer’s disease can be treated by targeting amyloid-β plaques and diagnosed in vivo by biomarkers, prompting the revision of criteria for the diagnosis and staging of this disease.
One of the most important consumers’ needs in their decision-making process is reduction of risks. On online platforms, trust is the most powerful tool for mitigating risks in making consumption decisions, especially in relation to tourism services that customers are unable to experience before the trip. In the digital age, trust is often mediated by information and communication technologies (ICT
Aim: To audit adherence to the Swedish paediatric guidelines for urinary tract infections (UTIs) in infants. Secondary objectives were to compare findings on imaging performed according to the guidelines with imaging without guideline support and to identify predictors of non-adherence. Methods: A prospective multicentre study of infants <1 year treated at paediatric hospitals for their first UTI.
Ecocriticism tends to acknowledge anthropomorphisms as a possible tool to create empathy for nonhumans, but in doing so mostly labels said tool as too sentimental for serious environmental literature. This paper aims to establish a categorisation of anthropomorphisms in media that allows a more diverse and detailed analysis of humanised nonhumans. It seeks to overcome the prevailing idea that anth
Let f be a holomorphic self-map of the unit disc. We show that if log(1 − | f (z)|) is integrable on a sub-arc of the unit circle, I , then the set of points where the function f has finite Carathéodory angular derivative on I is a countable union of Beurling–Carleson sets of finite entropy. Conversely, given a countable union of Beurling–Carleson sets, E , we construct a holomorphic self-map of t
This work presents a statistical approach for estimating and analyzing the downward transport pattern and distribution of soil water by the use of pattern analysis of space-time correlation structures. This approach, called the Space-time Correlation Field, is mainly based on the analyses of correlation functions simultaneously in the space and time domain.The overall purpose of this work is to de
This Letter introduces a novel, to the best of our knowledge, method for assessing fruit quality using white-light biospeckle displacement analysis. The primary aim is to demonstrate that speckle displacement behavior differs between healthy and decaying regions, offering a unique means of gauging bioactivity levels, a feature that has not been explored in previous biospeckle research. By examinin
