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This article outlines a numerical study on the benefit of using High-Performance/Strength Concrete for fabrication of concrete elements. For this purpose a comparison is done between the cost of existing beams with normal strength concrete and optimized beams made of High-Performance/Strength Concrete. A background is given concerning the most essential properties of High-Performance/Strength Conc
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The aim of the RAID project (Robot for Assisting the Integration of the Disabled) is to develop and demonstrate a prototype robotic workstation for use by disabled people. The RAID project is part of the European Community TIDE program (Technology for the socio-economic Integration of disabled and Elderly people). The robotized system is intended primarily for vocational use in an office environ
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We consider the elliptic-elliptic, focussing Davey-Stewartson equations, which have an explicit bright line soliton solution. The existence of a family of periodic solitons, which have the profile of the line soliton in the longitudinal spatial direction and are periodic in the transverse spatial direction, is established using dynamical systems arguments. We also show that the line soliton is lin
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The Grodsky packet storage model describes many features of insulin release, but at present more or less arbitrary simplifications are necessary. The consequences of various simplifications are discussed, especially with regard to identification of parameters thought to be of importance for glucose tolerance. In particular, the insulin release dynamics of the ordinary intravenous glucose tolerance
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We consider the problem of identifying structural influences of external inputs on steady-state outputs in a biological network model. We speak of a structural influence if, upon a perturbation due to a constant input, the ensuing variation of the steady-state output value has the same sign as the input (positive influence), the opposite sign (negative influence), or is zero (perfect adaptation),
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Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs. Moreover, no treatments exist to prevent the development of epilepsy in those at risk, despite an increasing understanding of the underlying molecular and cellular pathways. One of the major factors that have impeded rap
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Summary: Overweight and obesity constitute a major and increasing health and welfare problem throughout the world. Assessing the multifaceted mechanisms – biological, environmental and behavioural – behind this development is a crucial task in medical, social and economic sciences. We are, therefore, grateful to have been given the opportunity to, once again, discuss whether the risk of divorce ma
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In this article, the 2009 European League Against Rheumatism (EULAR) recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have been updated. The 2009 recommendations were on the management of primary small and medium vessel vasculitis. The 2015 update has been developed by an international task force representing EULAR, the European Renal Ass
