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forskare: kristina rydell-törmänen, roger hesselstrand klinik/institution: lungbiologi, lunds universitet e-post: kristina.rydell-tormanen@med.lu.se H Ö G T B L O D T R Y C K I L U N G A N I S T Ä L L E T F Ö R I A R M E N Den friska individen I kroppen cirkulerar blodet genom två kretslopp som visas schematiskt i fi gur 1; • Det stora kretsloppet, syste- miska cirkulationen, där det syresatta blo
https://www.vetenskaphalsa.se/wp-content/uploads/2011/11/ForskningensDag2011-4.pdf - 2026-07-12
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We have studied drug release and skin permeation from several different liquid crystalline lipid formulations that may be used to control the respective release rates. We have studied the release and permeation through human skin of a water-soluble and amphiphilic drug, propranolol hydrochloride, from several formulations prepared with monoolein and phytantriol as permeation enhancers and controll
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Pavements are constructed using several layers of materials, and their durability depends mainly on the stiffness modulus and thickness of these strata. Surface wave testing is an effective tool to measure the stiffness and thickness of pavement layers. However, measurements are still based on spot testing with fixed receivers and source. The typical large size of pavements and the cost of closing
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It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally impor
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The concentrations of water dimer are compared in Ne and p-H-2 matrices at low temperatures, using infrared spectroscopy. Additional data are given for o-D-2 and Ar matrices. For a given monomer concentration, the dimer concentration is significantly higher in solid Ne (or Ar) than in solid p-H-2. In p-H-2, the dimer concentration is only slightly higher than expected for a random distribution of
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Water-soluble chlorophyll-binding proteins (WSCPs) are interesting model systems for the study of pigment-pigment and pigment-protein interactions. While class IIa WSCP has been extensively studied by spectroscopic and theoretical methods, a comprehensive spectroscopic study of class IIb WSCP was lacking so far despite the fact that its structure was determined by X-ray crystallography. In this pa
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Galectins are a group of lactose-binding proteins widely distributed in nature. Twelve mammalian galectins have so far been identified, but their functions are to a large extent unknown. In this work we study galectin-1 in its interaction with human neutrophils, with regard to both cell surface binding and activation of the superoxide-producing NADPH-oxidase. We show that galectin-1 is able to act
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Rapporten behandlar arbetsmiljön vid termisk ogräsbekämpning. Metoden innebär att ogräset hettas upp med hjälp av gaslågor. Både stora fordonsburna och mindre handdrivna används. Det som från arbetsmiljösynpunkt är speciellt med metoden är de risker som är förknippade med gasolanvändningen. De allvarligaste problemen med de aggregat som studerats har varit heta och oskyddade plåtar, heta avgaser o
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Macroscopic phase separation in covalent sodium polyacrylate (PA) networks following the absorption of cetyltrimethylammonium bromide/chloride (CTAB/C) from aqueous solutions is studied experimentally and theoretically. The gels are shown to consist of a solvent-swollen polyelectrolyte network (core), surrounded by a dense surface phase (skin) of polyion/surfactant complexes. The effect of core sw
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Exposure of L. acidophilus CRL 639 cells to sublethal adaptive acid conditions (pH 5.0 for 60 min) was found to confer protection against subsequent exposure to lethal pH (pH 3.0). Adaptation, which only occurred in complex media, was dependent on de novo protein synthesis and was inhibited by amino acid analogues. There was no modification in the protein synthesis rate during adaptation, but the
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Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals and may be involved in the pathogenesis of chronic liver diseases (CLD) in humans. Antibody responses to cell surface proteins of H. pullorum, H. bilis, and H. hepaticus in serum samples from patients with CLD, a randomized population gro
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Popular Abstract in Swedish Ämnen i bröstmjölk kan få cancerceller att begå självmord - in vivo effekter och mekanismer för celldöd Sedan länge är det känt att bröstmjölk skyddar det ammande barnet mot infektioner och hjälper till att bygga upp des's immunförsvar. Ett skyddande ämne som kan bilda's av molekyler från bröstmjölk är HAMLET (human alpha-lactalbumin made lethal to tumor cell's), som kHAMLET (human alpha-lactalbumin made lethal to tumor cells), a molecular complex derived from human milk, is an interesting new tool in cancer research since it induces programmed cell death in tumor cells while leaving normal, differentiated cells unharmed. The in vivo effects of HAMLET were studied in a rat xenograft model of human glioblastoma. HAMLET reduced the tumor volume and delayed the o
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Mixtures of an amphiphilic graft copolymer in water/sodium bis(2-ethylhexyl) sulfosuccinate (AOT)/cyclohexane oil-continuous microemulsions are studied by the PGSE NMR technique and by viscometry. The graft copolymer has an oil-soluble poly(dodecyl methacrylate) backbone and water-soluble poly(ethylene glycol) side chains. Water, surfactant, and polymer self-diffusion coefficients can be measured
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This thesis has examined if there is any difference in the relationship between different risk factors and the cross-section of assets excess returns on the Swedish stock market between days when macroeconomic news is scheduled to be announced (announcement days) and other days (normal days). The Fama and Macbeth two-pass regression method have been used for investigating the hypothesis that annou
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Phantoms mimicking the specific mechanical and acoustic properties of human tissues are essential in the development and evaluation of novel ultrasound methods. In this work, various ultrasound phantoms are proposed to be used in the development of ultrasound methods to investigate the arterial walls longitudinal movements influence on the vasa vasorum circulation. The longitudinal movement of art
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Syfte: Uppsatsens syfte är att undersöka hur ett varumärke kan gå från att uppfattas som rent till att bli smutsigt. Med utgångspunkt i teorier kring rent och smutsigt, brand communities och subkulturer vill vi bidra till en ökad förståelse för vad som kan påverka ett varumärke negativt. Metod: Studien är genomförd med en kvalitativ forskningsmetod där den empiriska datainsamlingen har gjorts främ
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In its Advisory Opinion on the Legality of Nuclear Weapons the ICJ was unable to conclude definitely the legality or illegality of nuclear weapons in international law. Since then the Treaty on the Prohibition of Nuclear Weapons have been signed, with the aim of establishing a total prohibition on nuclear weapons. However, while the Treaty have an honourable aim, the lack of sufficient ratificatio
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The purpose of this thesis is to reach a better understanding of how people view gender equality and the equality-work conducted, in a male-dominated and public organization, like the Swedish Armed Forces. The study is based upon a qualitative research approach with an interpretative, hermeneutical perspective. Further, this has been done through semi-structured interviews and document studies as
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One of the most debated political events during 2016 was the referendum regarding the United Kingdom’s future in the European Union. Despite the many warnings received from economists the UK voters voted for ‘leave’, paving the way for Brexit. This thesis reviews some possible alternatives regarding the UK-EU relationship post Brexit and concludes that the economically best case scenario would be
