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In cystic fibrosis (CF) colonization of the airways with Pseudomonas aeruginosa is a major cause of deterioration and death. Host defence fails to clear the invading bacteria, which results in a chronic destructive inflammatory process. This thesis deals with factors in the interaction between bacteria and host defence that determine the extent of tissue damage caused by the bacteria. (I) Autoant
B-cell lymphoma (BCL) heterogeneity represents a key issue, often making the classification and clinical management of these patients challenging. In this pilot study, we outlined the first resolved view of BCL disease heterogeneity on the protein level by deciphering disease-associated plasma biomarkers, specific for chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma
Brigadier General Hossein Dehghan, a commander of the Islamic Revolutionary Guard Corps, has announced his candidacy for the Iranian presidential elections in June 2021. Dehghan has a toxic military background. In the 1980s he was responsible for the vicious crackdown on opponents of the Islamic regime, and he played a central role in the bombing of the US Marine barracks in Beirut that killed hun
AIMS: Tilt testing (TT) is recognized to be a valuable contribution to the diagnosis and the pathophysiology of vasovagal syncope (VVS). This study aimed to assess the influence of age on TT responses by examination of a large patient cohort.METHODS AND RESULTS: Retrospective data from three experienced European Syncope Units were merged to include 5236 patients investigated for suspected VVS by t
Objectives: Endovascular repair (ER) of popliteal artery aneurysm (PAA) is an alternative to open repair. However, there is no standardized protocol for when to opt for ER and the decision is therefore at the discretion of the clinician. This study aims to evaluate the adherence to the Instruction For Use (IFU) in patients undergoing ER for PAA and factors associated with stent graft patency at on
Detta arbete kick-startar AI (artificiell intelligens) för ledningsunderhåll i VA-branschen i Sverige. Arbetet med befintliga VA-nät är idag främst reaktivt; man reparerar läckor vartefter man blir varse dem, ibland till stora kostnader om läckan är omfattande och akut. Med denna artikel vill vi sätta fokus på proaktivt arbete med ledningsnät och diskutera riskanalys inom området. En ANN-modell soThis work kick-starts AI (artificial intelligence) for pipe management among Swedish water utilities. The current work with pipe management is mainly reactive; leaks are repaired after they are detected, sometimes with large costs if the leakage is extensive and critical. With this article, we want to focus on proactive pipe network management and discuss risk analysis in the field. A previously d
Purpose: This paper aims to comprehensively clarify the research status of thermal transport of supercritical aviation kerosene, with particular interests in the effect of cracking on heat transfer. Design/methodology/approach: A brief review of current research on supercritical aviation kerosene is presented in views of the surrogate model of hydrocarbon fuels, chemical cracking mechanism of hydr
B Corp certification is considered a viable instrument to support small and medium-sized enterprises (SMEs) in adopting sustainable practices. However, there is a lack of evidence to what extent this instrument can anchor sustainability at the core of SMEs. This study investigates the B Corp certification process of a SME, a craft brewery in southern Sweden, regarding the extent to which it helped
Polyclonal protein HC-IgA complexes (HC-IgA) were isolated from two different serum pools. Their hydrodynamic volumes were found to be slightly greater than that of monomeric IgA but less than that of dimeric IgA. Sodium dodecyl sulphate (SDS)-polyacrylamide gel electrophoresis of reduced and carboxymethylated complexes followed by immunoblotting showed that the complexes contained normal light an
Syftet med denna studie var dels att samla information om den sanitära status som gäller för Mafraqs deponi och dels att bedöma lakvattnets och grundvattnets kvalitet i dess närområde. Mafraqs deponi befinner sig på en av Jordaniens viktigaste akvifer och utgör därigenom ett potentielt hot mot grundvattnets kvalitet. I området runt om deponin används grundvattnet som dricksvatten och för konstbeva
Syftet med detta examensarbete är att pressentera ett antal tekniska lösningar för att förbättra säkerheten och kapaciteten i ställverk 59. Ställverk 59 är den vanligaste ställverkstypen på Trafikverkets järnvägsnät. Grundkonstruktionen är utvecklad på 1950-talet, men ställverkstypen nybyggs fortfarande trots konstruktionens ålder. Ända sedan järnvägen infördes har det funnits behov av att styra t
Are there such things as moral, rights and an inner sense of justice? Do they origin from God or are they something given by nature? If there are such things, should they be a part of the legal system? This essay has drawn its inspiration from this kind of thoughts and how they have been handled through history. The structure of the essay is two-folded. Part one is a historical review of the eme
In March 2011 the Swedish government appointed a committee to investigate and analyze the literature’s situation and the literature area. The committee will not investigate the conditions and positions of the actors on the book market, nor analyze the distribution of the National Arts Council’s literature support – a support with the purpose to encourage publication of quality literature with grea
Measles virus genotype B3 was isolated from patients during a measles outbreak in Copenhagen starting January 2006. Here we describe three cases: two children aged 9 and 22 months, respectively, and a 29-year-old man. All three patients were hospitalised. Several doctors examined both the children before the diagnosis of measles was established. The patients were not vaccinated against measles. Th
I detta papper försvarar jag Ayn Rands metaetik mot invändningar presenterade av Charles J King. Vad är roten till alla värden? Ayn Rand menar att det är livet som är det yttersta värde och som därför gör alla andra värden möjliga och nödvändiga. Charles J. King delar inte denna uppfattning utan menar istället att det som gör värden möjliga är inte livet, utan förmågan att ha begär. Jag säger att
